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γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling
DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds
Adenylyl cyclase activator
Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs
Potent AMPK inhibitor; also BMP type I receptor inhibitor
Anti-inflammatory glucocorticoid
Endogenous retinoic acid receptor agonist
Forskolin synthesized to Ancillary Material Grade
PDE inhibitor (non-selective)
High affinity PKC activator; also APP modulator
DAPT synthesized to Ancillary Material Grade
Activator of LKB1/AMPK; antidiabetic agent
Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs
Endogenous agonist of LPA1 and LPA2
Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
Potent inhibitor of Wnt/β-catenin signaling
Histone deacetylase inhibitor
Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs
Induces definitive endoderm formation in mouse and human ESCs
Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
Potent, reversible EGFR tyrosine kinase inhibitor
LDN 193189 synthesized to cGMP guidelines
DNA methyltransferase inhibitor
Synthetic retinoid; induces differentiation of stem cells
Highly potent and selective GSK-3 inhibitor
Intracellular cryoprotective agent
A 83-01 synthesized to Ancillary Material Grade
DNA methyltransferase and cytidine deaminase inhibitor
Dopamine receptor antagonist; antipsychotic
Induces neurogenesis in mature skeletal muscle cells
Potently induces chondrogenesis in MSCs
Selective inducer of neuronal differentiation in hippocampal neural progenitors
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
PKA signaling activator; promotes osteogenesis from hMSCs
High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
NAMPT activator; also proneurogenic and neuroprotective
Potent and selective Foxo1 inhibitor; orally bioavailable
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells