EC 23
Chemical Name: 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid
Purity: ≥99%
Biological Activity
EC 23 is a photostable synthetic retinoid; analog of ATRA (Cat. No. 0695). Displays similar activity to ATRA when tested on the embryonal carcinoma stem cell model TERA2.cl.SP12. Potently induces neural differentiation in human pluripotent embryonic stem cells.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation.
Christie et al.
Org.Biomol.Chem., 2008;6:3497 -
Synthetic retinoids: structure-activity relationships.
Barnard et al.
Chemistry, 2009;15:11430 -
Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins.
Maltman et al.
Mol.Biosyst., 2009;5:458
Product Datasheets
Citations for EC 23
The citations listed below are publications that use Tocris products. Selected citations for EC 23 include:
2 Citations: Showing 1 - 2
-
Tiotropium and Fluticasone Inhibit Rhinovirus-Induced Mucin Production via Multiple Mechanisms in Differentiated Airway Epithelial Cells.
Authors: Ying Et al.
Front Cell Infect Microbiol 2020;10:278
-
Morpho-Rheological Fingerprinting of Rod Photoreceptors Using Real-Time Deformability Cytometry.
Authors: Santos-Ferreira Et al.
Cytometry A 2019;
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for EC 23
There are currently no reviews for this product. Be the first to review EC 23 and earn rewards!
Have you used EC 23?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
