DMSO, sterile filtered
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Description: DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds
Alternative Names: Methyl sulfoxide
Chemical Name: Dimethyl sulfoxide
Purity: ≥99.9%
Biological Activity
DMSO, sterile filtered is a solvent with wide ranging applications in cell culture, cryopreservation and organic chemistry. DMSO dissolves both polar and nonpolar compounds. Improves responsiveness of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) to differentiation signals. DMSO is used in PCR to inhibit secondary structure formation by DNA template or primers.DMSO, Cell Cryopreserve Grade (Cat. No. 7726) also available.
Technical Data
M.Wt:
78.13
Formula:
C2H6OS
Purity:
≥99.9%
Storage:
Store at RT
CAS No:
67-68-5
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release.
Obis T, Besalduch N, Hurtado E, Nadal L, Santafe M, Garcia N, Tomas M, Priego M, Lanuza M, Tomas J
Mol Brain, 2015;8(0):8. -
A simple tool to improve pluripotent stem cell differentiation.
Chetty et al.
Nat.Methods, 2013;10:553 -
Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis
S Simón Serr, A Grönberg, L Longato, K Rombouts, J Kuo, M Gregory, S Moss, E Elmér, G Mazza, P Gallay, M Pinzani, MJ Hansson, R Massoumi
Cells, 2019;8(11):.
Product Datasheets
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Citations for DMSO, sterile filtered
The citations listed below are publications that use Tocris products. Selected citations for DMSO, sterile filtered include:
17 Citations: Showing 1 - 10
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Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice.
Authors: Sendo Et al.
Arthritis Res Ther 2019;21:184
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Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels.
Authors: Lively Et al.
Front Cell Neurosci 2018;12:115
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Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells.
Authors: Morizane and Bonventre
Nat Protoc 2017;12:195
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Relative Role of Akt, ERK and CREB in Alcohol-Induced Microglia P2X4R Receptor Expression.
Authors: Gofman Et al.
Alcohol Alcohol 2016;51:647
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Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons.
Authors: Zechel Et al.
Elife 2016;5
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The novel protein kinase C ε isoform modulates acetylcholine release in the rat neuromuscular junction.
Authors: Obis Et al.
J Neurophysiol 2015;8:80
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The novel protein kinase C ε isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release.
Authors: Obis Et al.
PLoS One 2015;8:8
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Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-α/EGFR signaling.
Authors: Ito Et al.
Mol Brain 2015;308:L1178
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The development of zebrafish tendon and ligament progenitors.
Authors: Chen
Development 2014;141:2035
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L-type Ca2+ channel responses to bay k 8644 in stem cell-derived cardiomyocytes are unusually dependent on holding potential and charge carrier.
Authors: Ji Et al.
Assay Drug Dev Technol 2014;12:352
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The dorsomedial hypothalamus mediates stress-induced hyperalgesia and is the source of the pronociceptive peptide cholecystokinin in the rostral ventromedial medulla.
Authors: Wagner Et al.
Am J Physiol Lung Cell Mol Physiol 2013;238:29
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Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury.
Authors: Hughes Et al.
Mol Brain 2013;154:1680
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Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.
Authors: Hermanson Et al.
J Neuroendocrinol 2012;7:e43580
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Photoperiodic changes in endocannabinoid levels and energetic responses to altered signalling at CB1 receptors in Siberian hamsters.
Authors: Ho Et al.
Behav Brain Res 2012;24:1030
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Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4+ T cells to T-regulatory cells.
Authors: Olkhanud Et al.
Cancer Res 2011;71:3505
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GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.
Authors: Romo-Parra Et al.
Neuroscience 2008;99:1523
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Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.
Authors: Andäng Et al.
Nature 2008;451:460
FAQs
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What type of vial is Catalog # 3176, DMSO, supplied in?
The 5 mL and 25 mL size products are supplied in 5 mL glass vials. The 100 mL product is supplied in a 100 mL glass vial.
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