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Cdk inhibitor; potently inhibits cdk1 and cdk2; also inhibits CK1; acts as molecular glue
Molecular glue; pre-mRNA splicing modulator
Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone
α2 integrin inhibitor; anti-angiogenic
Molecular glue Degrader; induces ubiquitination and degradation of cyclin K
Molecular glue; induces degradation of CCNK and CDK12
Molecular glue; induces degradation of GSPT1/2
Molecular glue; induces degradation of BCL6
Molecular glue; induces degradation of NQAT1
Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system
Molecular glue Degrader of mutant β-catenin
RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).
STING agonist, molecular glue that causes oligomerization of STING
Potent molecular glue Degrader of BET proteins BRD4 and BRD2
Potent and selective CK1α molecular glue Degrader
Covalent allosteric NRF2 inhibitor
CBL-B intramolecular glue inhibitor