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NVS-STG2

Catalog #: 8120 Datasheet
Catalog # Availability Size / Price Qty
8120/10
8120/50
NVS-STG2 | CAS No. 3030588-01-0 | STING Agonists
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Description: STING agonist, molecular glue that causes oligomerization of STING

Chemical Name: 4-((4-(2-(tert-Butyl)-5,5-dimethyl-1,3-dioxan-2-yl)benzyl)amino)-3-methoxybenzoic acid

Purity: ≥98%

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Biological Activity

NVS-STG2 is a STING agonist. It induces oligomerization of human STING by binding to pockets between adjacent STING dimer transmembrane domains, acting as a molecular glue. NVS-STG2 elicits potent STING-mediated immune responses in cells and produces antitumor activities in hSTING knock-in mice.

Technical Data

M.Wt:
427.54
Formula:
C25H33NO5
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
3030588-01-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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