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CCT 369260

Catalog #: 7799 Datasheet
Catalog # Availability Size / Price Qty
7799/5
7799/25
CCT 369260 | CAS No. 2253878-44-1 | Molecular Glues
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Description: Molecular glue; induces degradation of BCL6

Chemical Name: rel-5-[[5-Chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-2H-benzimidazol-2-one

Purity: ≥98%

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Biological Activity

CCT 369260 acts as a potent BCL6 molecular glue Degrader (IC50 = 54 nM). It reduces BCL6 levels in a lymphoma xenograft mouse model. CCT 369260 is orally bioavailable.

Technical Data

M.Wt:
509
Formula:
C24H31ClF2N6O2
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2253878-44-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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