Lysine Methyltransferase Inhibitors: Products

EZH2 histone methyltransferase inhibitor

Very high affinity and selective EZH2 inhibitor

3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade

SETD8 inhibitor; also CDK4 inhibitor

GLP and G9a inhibitor

Potent and selective SETD7 inhibitor

Potent and selective EZH2/EZH1 inhibitor

Potent G9a and GLP inhibitor

Selective G9a and GLP inhibitor

SUV39H1 inhibitor

Potent and selective G9a and GLP inhibitor

Potent and selective G9a/GLP inhibitor

Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)

Highly potent DOT1L inhibitor

Highly potent and selective DOT1L inhibitor; cell permeable

Potent and selective SAM-competitive EZH2 inhibitor

Potent and selective SAM-competitive EZH2 inhibitor

Potent and selective SUV420H1/H2 inhibitor

Highly potent and SAM-competitive EZH2 inhibitor

Potent and selective SMYD3 inhibitor

Nuclear receptor-binding SET domain (NSD) 3 antagonist; selectively binds PWWP1 domain

Antagonizes PWWP1 interaction with nucleosomal H3K36me2, alters NSD2 nucleolar localization

Selective ASH1L histone methyltransferase inhibitor

Potent and selective EED inhibitor

NSD2 Degrader (PROTAC®)