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BAY 6035

Catalog #: 6561 Datasheet
Catalog # Availability Size / Price Qty
6561/5
6561/25
BAY 6035 | CAS No. 2247890-13-5 | Lysine Methyltransferase Inhibitors
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Description: Potent and selective SMYD3 inhibitor

Chemical Name: (2S)-1-(3-Azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide

Purity: ≥98%

Product Details
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Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

BAY 6035 is a potent SMYD3 inhibitor (IC50 = 70 nM for inhibition of MEKK2 methylation in cells). Exhibits >100-fold selectivity for SMYD3 over other histone methyltransferases.

Technical Data

M.Wt:
396.48
Formula:
C22H28N4O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2247890-13-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BAY-6035 probe summary on the SGC website.

Product Datasheets

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