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Mitochondrial VDAC modulator; also Ferroptosis activator
HMG-CoA reductase inhibitor
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
Negative control for 1S,3R-RSL3 (Cat. No. 6118)
Irreversible γ-glutamylcysteine synthetase (γ-GCS) inhibitor; induces ferroptosis
Inhibits glutathione peroxidase (GPX4); induces ferroptosis