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Potent and selective BET bromodomain inhibitor; cell permeable
(+)-JQ1 based Degrader (PROTAC®) that preferentially degrades BRD4
BET bromodomain inhibitor; also promotes differentiation of hiPSCs into megakaryocytes
Potent and selective BRD9 Degrader (PROTAC®)
ERK5/BMK1 inhibitor; also BRD4 inhibitor
Potent and selective BRD9 inhibitor
Negative Control for MZ 1 (Cat. No. 6154)
(+)-JQ1 based Degrader (PROTAC®) targeting BET bromodomains, active in vivo
Potent BRD9 Degrader (PROTAC®)
Potent and selective (+)-JQ1 based Degrader (PROTAC®) targeting BET bromodomains, active in vivo
BET bromodomain inhibitor
CBP inhibitor; cell permeable
Broad spectrum bromodomain inhibitor
Potent CBP/p300 BRD inhibitor
Potent and selective SMARCA2/4 and polybromo 1 inhibitor
BET bromodomain inhibitor; arrests cell cycle at G1 phase
Potent and selective BRPF bromodomain inhibitor
Potent and selective BRD9 and BRD7 inhibitor; orally active
Negative control for (+)-JQ1
Selective BRD7 and BRD9 inhibitor
Negative Control for LP 99
Potent and selective CECR2 inhibitor
Potent and selective BRD1 and TAF1 inhibitor
Negative control for TP 472
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
BET bromodomain inhibitor; orally bioavailable
Potent and selective BRPF1 inhibitor
Negative control for GSK 6853
High affinity and selective PCAF bromodomain inhibitor
(+)-JQ1 based PROTAC® with selectivity for BRD4
Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.
CECR2 and BPTF/FALZ inhibitor
Potent and selective BRD7/9 Degrader (PROTAC®)
Negative control for VZ 185 (Cat. No. 6936)
Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
Potent and selective trivalent BET Bromodomain Degrader (PROTAC®)
Negative control for SIM1 (Cat. No. 7432)
Potent and selective pan-BD2 inhibitor; orally bioavailable
Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor
Selective MLLT1/3 inhibitor
Functionalized BET bromodomain ligand; precursor for Tag Degraders
Potent and selective SMARCA4/2 inhibitor
Potent SMARCA2/4 inhibitor
Potent and selective ATAD2 bromodomain inhibitor
BET bromodomain Degrader (PROTAC®); also potent Hedgehog pathway inhibitor
BRG1/SMARCA4 Degrader (PROTAC®)