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Potent and selective BCRP inhibitor
Inhibitor of P-gp-mediated MDR
Potent CysLT1 (LTD4) inverse agonist. Also MRP1 inhibitor
Selective MRP1 and P-gp inhibitor
Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor
High affinity P-gp inhibitor
Potent P-glycoprotein (P-gp) inhibitor