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Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
Y-27632 synthesized to cGMP guidelines
SB 431542 synthesized to cGMP guidelines
Selective inhibitor of TGF-βRI, ALK4 and ALK7
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
PORCN inhibitor; inhibits Wnt processing and secretion
Selective inhibitor of p38 MAPK
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
Potent, selective GSK-3 inhibitor
Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogenesis
Potent GSK-3 inhibitor; also inhibits cdks
Potent pan-caspase inhibitor
Minimal recognition sequence for integrin binding; potent integrin inhibitor
Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability
Potent and selective Lck and Src inhibitor; also inhibits SIK
Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo
A 83-01 synthesized to Ancillary Material Grade
Selective PPARγ agonist; antidiabetic agent
Enhances survival of human ESCs following enzymatic dissociation
CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal
Heparin sulfate antagonist
T3 synthesized to Ancillary Material Grade
Sterile-filtered 10 mM solution of Y-27632 pre-dissolved in water
Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons
Cell culture supplement for improving stem cell survival