Yhhu 3792
Chemical Name: 5-(3-Methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]-2,4-quinazolinediamine hydrochloride
Purity: ≥98%
Biological Activity
Yhhu 3792 is a notch signaling pathway activator; enhances the self-renewal capability of neural stem cells (NSCs) via Notch signaling pathway activation in vitro and in vivo. Promotes the expression of Notch target genes, Hes3 and Hes5. Expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) after chronic administration in mice. Increases the spatial and episodic memory in mice.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
Product Datasheets
Citation for Yhhu 3792
The citations listed below are publications that use Tocris products. Selected citations for Yhhu 3792 include:
1 Citation: Showing 1 - 1
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Interleukin-10 regulates goblet cell numbers through Notch signaling in the developing zebrafish intestine.
Authors: Srustidhar Et al.
Mucosal Immunol 2022;15:940-951
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