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VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
Potent VEGFR inhibitor; also inhibits other RTKs
Highly potent FLT3 inhibitor
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
Potent FLT3 inhibitor; also potently inhibits AXL