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Potent tankyrase inhibitor
XAV 939 synthesized to cGMP guidelines
Inhibits TCF/β-catenin-mediated transcription
Potent inhibitor of Wnt/β-catenin signaling
Wnt signaling inhibitor; inhibits β-catenin-transcription factor interactions
Potent p38 MAPK inhibitor; anti-inflammatory
Potent tankyrase inhibitor
Inhibitor of Wnt/β-catenin signaling
Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma