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GLI antagonist; inhibits Hedgehog (Hh) signaling
Core binding factor inhibitor; attenuates hematopoiesis
High affinity Myc inhibitor
Potent and selective CREB inhibitor
Inhibits c-Myc-Max dimerization
Hepatocyte nuclear factor 4α (HNF4α) antagonist
Cryptochrome protein stabilizer; lengthens circadian period
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
High affinity Nur77 agonist
Potent and selective Foxo1 inhibitor; orally bioavailable
Steroid receptor coactivator 3 (SRC-3) inhibitor
TRIM24 Degrader (PROTAC®)
Selective inhibitor of ATF6α; sensitizes cells to ER stress
Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling