Home / MYC Inhibitors / KJ Pyr 9

KJ Pyr 9

Catalog #: 5306
2 Citations Datasheet
Catalog # Availability Size / Price Qty
5306/50
5306/10
KJ Pyr 9 | CAS No. 581073-80-5 | MYC Inhibitors
1 Image
Description: High affinity Myc inhibitor

Chemical Name: 4-[2-(2-Furanyl)-6-(4-nitrophenyl)-4-pyridinyl]benzamide

Purity: ≥98%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

KJ Pyr 9 is a high affinity Myc inhibitor (Kd = 6.5 nM). Disrupts Myc-Max interaction. Inhibits Myc-dependent cancer cell line proliferation in vitro. Inhibits growth of MDA-MB-231 breast cancer cell xenografts in mice. Brain penetrant.

Technical Data

M.Wt:
385.37
Formula:
C22H15N3O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
581073-80-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Inhibitor of MYC identified in a Kröhnke pyridine library.
    Hart et al.
    Proc.Natl.Acad.Sci.U.S.A., 2014;111:12556

Product Datasheets

Citations for KJ Pyr 9

The citations listed below are publications that use Tocris products. Selected citations for KJ Pyr 9 include:

2 Citations: Showing 1 - 2

  1. Acute liver failure is regulated by MYC- and microbiome-dependent programs.
    Authors: Ana Et al.
    Nat Med  2020;26:1899-1911
  2. Downregulation of ribosome biogenesis during early forebrain development.
    Authors: Chau Et al.
    Elife.  2018;:e36998

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for KJ Pyr 9

There are currently no reviews for this product. Be the first to review KJ Pyr 9 and earn rewards!

Have you used KJ Pyr 9?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.