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Potent farnesyl diphosphate (FPP) synthase inhibitor
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
Ras signaling inhibitor; inhibits Ack1 and GCK
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
Mutation-selective inhibitor of KRASG12C