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Selective IGF1R inhibitor
High affinity insulin-like growth factor-I binding protein IGFBP inhibitor
Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
ATP-competitive inhibitor of IGF1R
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
Potent and selective dual inhibitor of the IGF-1 receptor and insulin receptor