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Rucaparib camsylate

Catalog #: 6230 Datasheet
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6230/50
Rucaparib camsylate | CAS No. 1859053-21-6 | Poly(ADP-ribose) Polymerase Inhibitors
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Description: PARP inhibitor
Alternative Names: CO-338

Chemical Name: 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid

Purity: ≥98%

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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Rucaparib camsylate is a PARP inhibitor. Chemosensitizes colorectal cancer cells to Temozolomide (Cat. No. 2706) and Topotecan (Cat. No. 4562) in vitro and in vivo.

Technical Data

M.Wt:
555.66
Formula:
C19H18FN3O.C10H16O4S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1859053-21-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Background References

  1. Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.
    Thomas et al.
    Mol.Cancer Ther., 2007;6:945

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