Ro 90-7501

Catalog #: 2408 Datasheet

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2408/10
2408/50

Ro 90-7501 | CAS No. 293762-45-5 | Amyloid beta Peptide Inhibitors

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Description: Inhibitor of Aβ42 fibril formation

Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine

Purity: ≥98%

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Product Details

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Ro 90-7501 is an inhibitor of amyloid β42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC₅₀ = 2 μM).

Technical Data

M.Wt:

340.39

Formula:

C₂₀H₁₆N₆

Solubility:

Soluble to 10 mM in 1eq. HCl and to 100 mM in DMSO

Purity:

≥98%

Storage:

Store at +4°C

CAS No:

293762-45-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.
Bohrmann et al.
J.Struct.Biol., 2000;130:232

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