Pritelivir
Chemical Name: N-[5-(Aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)benzeneacetamide
Purity: ≥98%
Biological Activity
Pritelivir is a potent and selective herpes simplex virus (HSV) helicase primase inhibitor. Pritelivir inhibits viral replication in Vero cells (IC50 = 0.02 μM for HSV-1 and HSV-2). It also reduces β-amyloid and P-tau levels in Vero cells. Pritelivir is active against clinical isolates and porcine and bovine HSV strains but displays reduced activity against varicella zoster virus and cytomegalovirus in vitro. In addition, the compound exhibits antiviral activity in HSV infected mice.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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