Mouse CD117/c-kit APC-conjugated Antibody Summary
Gln25-Thr519 (Ala207Glu)
Accession # P05532
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of CD117/c-kit in Mouse Splenoctyes by Flow Cytometry. Mouse splenocytes gated on hematopoietic lineage negative cells were stained with Rat Anti-Mouse CD117/c-kit APC-conjugated Monoclonal Antibody (Catalog # FAB1356A) and Rat Anti-Mouse Sca-1/Ly6 PE-conjugated Monoclonal Antibody (Catalog # FAB1226P). Quadrant markers were set based on control antibody staining (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
Background: CD117/c-kit
SCF R is also known as the c-kit proto-oncogene protein and as CD117. Together with its ligand, stem cell factor (also called c-kit ligand or mast cell growth factor), SCF R plays an essential role in gametogenesis, melanogenesis, and hematopoiesis. SCF R is expressed in hematopoietic progenitor cells, normal B and T lymphocyte progenitors, mast cells, germ cells, melanocytes, neurons, glial cells, placenta, kidney, lung, and gut. In addition, SCF R expression has also been reported in several human tumor cell lines (1,2).
- Broudy, V. (1997) Blood 90:1345.
- Vliagoftis, H. et al. (1997) J. Allergy Clin. Immunol. 100:435.
Product Datasheets
Citation for Mouse CD117/c-kit APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
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Maternal high-fat diet results in microbiota-dependent expansion of ILC3s in mice offspring
Authors: ST Babu, X Niu, M Raetz, RC Savani, LV Hooper, J Mirpuri
JCI Insight, 2018-10-04;3(19):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
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