Lamotrigine isethionate
Chemical Name: 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine isethionate
Purity: ≥99%
Biological Activity
Lamotrigine isethionate is a water-soluble salt of lamotrigine (Cat. No. 1611). Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture.
Zona and Avoli
Epilepsia, 1997;38:522 -
Cardioprotective effect of lamotr. after focal ischemia in rats.
Smith and Meldrum
Stroke, 1995;26:117 -
Modulation of calcium and potassium currents by lamotr.
Grunze et al.
Neuropsychobiology, 1998;38:131 -
Neurochemical and behavioral aspects of lamotr.
Leach et al.
Epilepsia, 1991;32:S4
Product Datasheets
Citation for Lamotrigine isethionate
The citations listed below are publications that use Tocris products. Selected citations for Lamotrigine isethionate include:
1 Citation: Showing 1 - 1
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Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1.
Authors: Madry Et al.
Neuron 2018;97:299
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