Kenpaullone

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. How selective are pharmacological inhibitors of cell-cycle-regulating cyclin-dependent kinases?
   Jorda et al.
   J.Med.Chem., 2018;61:9105
2. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.
   Lyssiotis et al.
   Proc.Natl.Acad.Sci.U.S.A., 2009;106:8912
3. Cell cycle targets in novel anticancer drug discovery.
   Buolamwini
   Curr.Pharm.Des., 2000;6:379
4. Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity.
   Schultz et al.
   J.Med.Chem., 1999;42:2909
5. Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases.
   Zaharevitz et al.
   Cancer Res., 1999;59:2566

Product Datasheets