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Covidcil-19

Catalog #: 7485 Datasheet
Catalog # Availability Size / Price Qty
7485/50
7485/10
Covidcil-19 | CAS No. 1225177-95-6 | Antiviral Compounds
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Description: Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency

Chemical Name: 3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid

Purity: ≥98%

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Biological Activity

Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency in cells. Covidcil-19 inhibits viral propagation and reduces viral infectivity by > 3.5 orders of magnitude.

Technical Data

M.Wt:
294.31
Formula:
C16H14N4O2
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1225177-95-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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