CNV Dopamine
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Description: Caged dopamine; photolysed by UV light
Purity: ≥98%
Biological Activity
CNV Dopamine is a carboxynitroveratryl (CNV)-caged dopamine (Cat. No. 3548); releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D2 receptors. Displays no decrease in current (rundown) with UV light flash duration of up to 100 ms. Pharmacologically inactive prior to photolysis.Technical Data
M.Wt:
392.36
Formula:
C18H20N2O8
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in water
Purity:
≥98%
Storage:
Store at -20°C
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Desensitized D2 autoreceptors are resistant to trafficking.
Robinson et al.
Sci.Rep., 2017;7:4379
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