Home / VCAM-1/CD106 / Human VCAM-1/CD106 Antibody

Human VCAM-1/CD106 Antibody

Catalog #: MAB809
7 Citations Datasheet
Catalog # Availability Size / Price Qty
MAB809-SP
MAB809-100
MAB809-500
Product Details
Citations (7)
FAQs
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human VCAM-1/CD106 Antibody Summary

Species Reactivity
Human
Specificity
Detects recombinant human VCAM-1 in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG1 Clone # HAE-2Z
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Human VCAM-1
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample

Human VCAM-1/CD106 Sandwich Immunoassay

Recommended Concentration
Reagent
ELISA Capture (Matched Antibody Pair)
2-8 µg/mL 

Use in combination with:

Detection Reagent: Human VCAM‑1/CD106 Biotinylated Antibody (Catalog # BAF809)

Standard: Recombinant Human VCAM-1/CD106 Protein, CF (Catalog # 809-VR)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VCAM-1/CD106

Vascular cell adhesion molecule (VCAM-1) is expressed on the surface of activated endothelial cells and macrophages. It binds to leukocyte integrins VLA-4 and  alpha 4 beta 7 to promote leukocyte adhesion at sites of inflamed vasculature.

Long Name
Vascular Cell Adhesion Molecule 1
Entrez Gene IDs
7412 (Human); 22329 (Mouse)
Alternate Names
CD106 antigen; CD106; DKFZp779G2333; INCAM-100; L1CAM; MGC99561; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; V-CAM 1; VCAM1; VCAM-1

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Citations for Human VCAM-1/CD106 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

7 Citations: Showing 1 - 7
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  1. Increased extracellular vesicles (EVs) related to T cell-mediated inflammation and vascular function in familial hypercholesterolemia
    Authors: Morten Hjuler Nielsen, Rikke Bæk, Malene Moller Jorgensen, Maiken Mellergaard, Aase Handberg
    Atherosclerosis Plus
  2. An Anti-Human ICAM-1 Antibody Inhibits Rhinovirus-Induced Exacerbations of Lung Inflammation
    Authors: Stephanie Traub, Alexandra Nikonova, Alan Carruthers, Rebecca Dunmore, Katherine A. Vousden, Leila Gogsadze et al.
    PLoS Pathogens
  3. Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells
    PLoS ONE, 2016-12-01;11(12):e0167361.
    Species: Human
    Sample Types: Whole Cells
    Applications: ELISA Development
  4. The impact of various preanalytical treatments on the phenotype of small extracellular vesicles in blood analyzed by protein microarray.
    Authors: Baek R, Sondergaard E, Varming K, Jorgensen M
    J Immunol Methods, 2016-08-24;438(0):11-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis.
    Authors: Zhao X, Qureshi F, Eastman PS, Manning WC, Alexander C, Robinson WH, Hesterberg LK
    J. Immunol. Methods, 2012-02-17;378(1):72-80.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Development
  6. Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes.
    Authors: Otterdal K, Smith C, Oie E, Pedersen TM, Yndestad A, Stang E, Endresen K, Solum NO, Aukrust P, Damas JK
    Blood, 2006-08-01;108(3):928-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: ELISA Development
  7. Potentials and capabilities of the Extracellular Vesicle (EV) Array.
    Authors: Jorgensen MM, Baek R, Varming K.
    J Extracell Vesicles

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