VH 101, acid

Catalog #: 7758 Datasheet
Catalog # Availability Size / Price Qty
7758/50
VH 101, acid | CAS No. 2408341-97-7 | Degrader Building Blocks
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Description: VHL ligand, carboxylic acid functionalized at the benzylic position

Chemical Name: (S)-3-[[[(2S,4R)-1-[(S)-2-(1-Fluorocyclopropan-1-ylcarbonylamino)-3,3-dimethylbutanoyl]-4-hydroxypyrrolidin-2-yl]carbonyl]amino]-3-[4-(4-methylthiazol-5-yl)phenyl]propanoic acid

Purity: ≥98%

Product Details
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Biological Activity

VH 101, acid is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand with carboxylic acid handle at the benzylic position ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
574.67
Formula:
C28H35FN4O6S
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2408341-97-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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