VH 032 amide-alkylC9-acid

Catalog #: 7404 Datasheet

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VH 032 amide-alkylC9-acid | CAS No. 2172819-78-0 | Degrader Building Blocks

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Description: VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternative Names: (S,R,S)-AHPC-C9-COOH

Chemical Name: 11-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecanoic acid

Purity: ≥95%

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Biological Activity

Functionalized von-Hippel-Lindau protein (VHL) ligand for PROTAC^® research and development; incorporates an E3 ligase ligand plus an alkylC9 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:

628.83

Formula:

C₃₃H₄₈N₄O₆S

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

2172819-78-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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