UBP 301
Chemical Name: (αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
Purity: ≥98%
Biological Activity
UBP 301 is a potent kainate receptor antagonist (apparent Kd = 5.94 μM). Displays ~ 30-fold selectivity over AMPA receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists.
More et al.
Br.J.Pharmacol., 2003;138:1093
Product Datasheets
Citation for UBP 301
The citations listed below are publications that use Tocris products. Selected citations for UBP 301 include:
1 Citation: Showing 1 - 1
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Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals.
Authors: Cassé Et al.
J Neurosci 2012;32:5186
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