Tocriscreen 2.0 Micro
Biological Activity
Tocriscreen 2.0 Micro is a a library of 1280 biologically active compounds from the Tocris catalog. The compounds within this bioactive compound library cover a wide range of pharmacological targets and research areas. Compounds are supplied pre-dissolved in 15 μL 10 mM DMSO solutions. A larger volume is available as Tocriscreen 2.0 Mini (Cat. No. 7151).This library replaces the Tocriscreen Plus Micro (Cat. No. 6455).
For more information on the Tocriscreen 2.0 Compound Libraries, please download our informative flyer.
If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.
Key Format and Product Details
- 96-well microplate format with peelable foil seal
- Compounds arranged 80 per plate with 16 plates per library
- Pre-dissolved in DMSO
- Many compounds are exclusive to Tocris
- Unique library with low overlap
- Full chemical and biological data available
- Exceptional purity
Note: Due to the small volume of this product, please ensure the liquid has settled to the bottom of the well before removing the foil seal.
- This library is supplied in a Corning Microplate; recommended centrifugation for this plate is 1000g or less
The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%).
Request Compound List
A list of the compounds available in the Tocriscreen 2.0 Micro can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Cell-based potassium ion channel screening using the FluxORTM assay.
Beacham et al.
J.Biomol.Screen., 2010;15:44 -
Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules.
Li et al.
Cell Research, 2011;21:196 -
Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.
Hattori et al.
Proc.Natl.Acad.Sci.USA, 2010;107:3546 -
Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons.
Li et al.
Cell Stem Cell, 2015;17:195 -
Small molecules enhance CRISPR genome editing in pluripotent stem cells.
Yu et al.
Cell Stem Cell, 2015;16:142
Product Datasheets
Citations for Tocriscreen 2.0 Micro
The citations listed below are publications that use Tocris products. Selected citations for Tocriscreen 2.0 Micro include:
12 Citations: Showing 1 - 10
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Development of a high-throughput screening platform to identify new therapeutic agents for Medulloblastoma Group 3.
Authors: Fallon Et al.
SLAS Discov. 2024;29:100147
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A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer.
Authors: Cetin Et al.
Cell Chem.Biol. 2024;
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A quenched size-expanded nucleotide reports activity of the leukemia biomarker Terminal deoxynucleotidyl Transferase (TdT).
Authors: Pals Et al.
Angew.Chem.Int.Ed.Engl. 2023;62:e202302796
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Advanced human iPSC-based preclinical model for Parkinson�s disease with optogenetic alpha-synuclein aggregation.
Authors: Kim Et al.
Cell Stem Cell 2023;30:973
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Discovery of novel cardiac troponin activators using fluorescence polarization-based high throughput screening assays.
Authors: Parijat Et al.
Sci.Rep. 2023;13:5216
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Repurposing small molecules for nephronophthisis and related renal ciliopathies.
Authors: Benmerah Et al.
Kidney Int. 2023;104:245
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NMDA Receptor Antagonists Degrade Lipofuscin via Autophagy in Human Retinal Pigment Epithelial Cells
Authors: Lee & Jeong Et al.
Medicina (Kaunas) 2022;58:1129
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Screening the TocriscreenTM bioactive compound library in search for inhibitors of Candida biofilm formation.
Authors: Abduljalil Et al.
APMIS 2022;130:568
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Identification of a novel specific small-molecule melanocortin-2-receptor antagonist.
Authors: Forfar Et al.
Endocr Connect 2022;11:e220338
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Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery.
Authors: Gull Et al.
Cold Spring Harb.Protoc. 2022;
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Ultrasensitive small molecule fluorogenic probe for human heparanase.
Authors: Liu Et al.
Chem Sci 2020;12:239
FAQs
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