Thalidomide 4'-oxyacetamide-PEG2-amine

Catalog #: 6967 Datasheet
Catalog # Availability Size / Price Qty
6967/25
Thalidomide 4'-oxyacetamide-PEG2-amine | CAS No. 2376990-30-4 | Degrader Building Blocks
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Description: Cereblon ligand with PEG linker and terminal amine for onward chemistry
Alternative Names: Thalidomide - linker 14

Chemical Name: N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride

Purity: ≥95%

Product Details
Reviews

Biological Activity

Thalidomide 4'-oxyacetamide-PEG2-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG linker with ethylamine terminal ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Thalidomide - linker 14

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
498.92
Formula:
C21H26N4O8.HCl
Solubility:
Soluble to 50 mM in DMSO and to 50 mM in DMF
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2376990-30-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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