tDHU, acid

Catalog #: 7773 Datasheet
Catalog # Availability Size / Price Qty
7773/50
tDHU, acid | CAS No. 2377643-37-1 | Degrader Building Blocks
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Description: Functionalized cereblon ligand for PROTAC development

Chemical Name: 4-Methyl-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)benzoic acid

Purity: ≥95%

Product Details
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Biological Activity

tDHU, acid is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a benzoic acid functional handle for ready conjugation to a linker/target protein ligand.

Part of a range of functionalized tool molecules for PROTAC® Degrader R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
248.24
Formula:
C12H12N2O4
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2377643-37-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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