TBCA
Chemical Name: (2E)-3-(2,3,4,5-Tetrabromophenyl)-2-propenoic acid
Purity: ≥98%
Biological Activity
TBCA is a selective CK2 inhibitor (IC50 = 110 nM). Exhibits selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases. Reduces viability of Jurkat cells in vitro.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors.
Pagano et al.
Chembiochem., 2007;8:129
Product Datasheets
Citation for TBCA
The citations listed below are publications that use Tocris products. Selected citations for TBCA include:
1 Citation: Showing 1 - 1
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Acupuncture elicits neuroprotective effect by inhibiting NAPDH oxidase-mediated reactive oxygen species production in cerebral ischaemia.
Authors: Shi Et al.
J Virol 2015;5:17981
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