Home / Src Family Kinase Inhibitors / Squarunkin A hydrochloride

Squarunkin A hydrochloride

Catalog #: 6364 Datasheet
Catalog # Availability Size / Price Qty
6364/50
6364/10
Squarunkin A hydrochloride | CAS No. 2253744-55-5 | Src Family Kinase Inhibitors
1 Image
Description: UNC119 chaperone-cargo interaction inhibitor; disrupts Src activation

Chemical Name: Ethyl 4-((3,4-dioxo-2-((2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)amino)cyclobut-1-en-1-yl)amino)piperidine-1-carboxylate hydrochloride

Purity: ≥98%

Product Details
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Squarunkin A hydrochloride is a potent inhibitor of UNC119 chaperone protein-cargo interaction (IC50 = 10 nM for inhibition of UNC119A - myristoylated Src N-terminal peptide interaction). Disrupts activation of Src kinase in vitro.

Technical Data

M.Wt:
560.01
Formula:
C25H32F3N5O4.HCl
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2253744-55-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Small-molecule inhibition of the UNC119-cargo interaction.
    Mejuch et al.
    Angew.Chem.Int.Ed., 2017;56:6181

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Squarunkin A hydrochloride

There are currently no reviews for this product. Be the first to review Squarunkin A hydrochloride and earn rewards!

Have you used Squarunkin A hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.