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SLU-PP-332

Catalog #: 8112 Datasheet
Catalog # Availability Size / Price Qty
8112/50
8112/10
SLU-PP-332 | CAS No. 303760-60-3 | Estrogen and Related Receptor Agonists
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Description: Potent pan-ERR agonist

Chemical Name: (E)-4-Hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide

Purity: ≥98%

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Biological Activity

SLU-PP-332 is a potent and selective pan estrogen related receptor (ERR) agonist (EC50 values are 98 nM, 230 nM and 430 nM for ERRα, ERRβ and ERRγ respectively). In a mouse model of metabolic syndrome SLU-PP-332 increases energy expenditure and fatty acid oxidation, decreases fat mass, and improves insulin sensitivity. Also increases mitochondrial respiration in vitro.

Technical Data

M.Wt:
290.32
Formula:
C18H14N2O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
303760-60-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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