Simple Plex Human Proprotein Convertase 9/PCSK9 Cartridge
Simple Plex Human Proprotein Convertase 9/PCSK9 Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay’s minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Product Summary
Precision
Serum, EDTA Plasma, Heparin Plasma
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 22 | 22 |
| Mean (pg/mL) | 296 | 17116 | 292 | 17472 |
| Standard Deviation | 19.6 | 842 | 18.3 | 1101 |
| CV% | 6.6 | 4.9 | 6.3 | 6.3 |
Recovery
Recovery was not necessary as PCSK9 shows natural linearity data from a neat sample to a 1:16 dilution.
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: Proprotein Convertase 9/PCSK9
This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing.
FAQs
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