S 2101
Chemical Name: (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride
Purity: ≥98%
Biological Activity
S 2101 is a LSD1 inhibitor (IC50 = 990 nM; Ki = 610 nM). Exhibits selectivity for LSD1 over MAO-B and MAO-A (Ki values are 17 and 110 μM, respectively).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1.
Mimasu et al.
Biochemistry, 2010;49:6494
Product Datasheets
Citation for S 2101
The citations listed below are publications that use Tocris products. Selected citations for S 2101 include:
1 Citation: Showing 1 - 1
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Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1.
Authors: Chris Et al.
Elife 2020;9
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