RU 24969 hemisuccinate
Chemical Name: 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate
Purity: ≥99%
Biological Activity
RU 24969 hemisuccinate is a potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor.
Gudermann et al.
Mol.Pharmacol., 1993;43:412 -
Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats.
Tomkins and O'Neill
Pharmacol.Biochem.Behav., 2000;66:129 -
Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antiDArgic properties.
Guillaume et al.
Eur.J.Med.Chem., 1987;22:33
Product Datasheets
Citation for RU 24969 hemisuccinate
The citations listed below are publications that use Tocris products. Selected citations for RU 24969 hemisuccinate include:
1 Citation: Showing 1 - 1
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Effects of oxyt. on Serotonin 1B Agonist-induced Autism-like Behavior in Mice
Authors: Lawson Et al.
Behavioural Brain Research 2016;314:52
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