(RS)-(Tetrazol-5-yl)glycine
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Description: Highly potent NMDA agonist
Purity: ≥98%
Biological Activity
(RS)-(Tetrazol-5-yl)glycine is a potent NMDA receptor agonist, approximately 20 times more active than NMDA.Technical Data
M.Wt:
143.1
Formula:
C3H5N5O2
Solubility:
Soluble to 50 mM in water
Purity:
≥98%
Storage:
Store at RT
CAS No:
138199-51-6
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Diffentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity.
Arnt et al.
Eur.J.Pharmacol., 1995;285:289 -
NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S)cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid.
Moroni et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1995;351:371 -
D,L-(Tetrazol-5-yl)glycine a novel and highly potent NMDA receptor agonist.
Schoepp et al.
Eur.J.Pharmacol., 1991;203:237
Product Datasheets
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