(RS)-(±)-Sulpiride

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0894/100
(RS)-(±)-Sulpiride | CAS No. 15676-16-1 | Non-selective Dopamine Receptor Antagonists
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Description: Standard selective D2-like antagonist

Chemical Name: (RS)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide

Purity: ≥98%

Product Details
Citations (7)
Supplemental Products
Reviews

Biological Activity

(RS)-(±)-Sulpiride is a standard D2-like dopamine receptor antagonist.

S-enantiomer also available.

Technical Data

M.Wt:
341.42
Formula:
C15H23N3O4S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
15676-16-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. DA receptor pharmacology.
    Seeman and Van Tol
    Trends Pharmacol.Sci., 1994;15:264
  3. DA D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective.
    Seeman and Van Tol
    Eur.J.Pharmacol., 1993;233:173

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Citations for (RS)-(±)-Sulpiride

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