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Rilpivirine

Catalog #: 7684 Datasheet
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7684/10
7684/50
Rilpivirine | CAS No. 500287-72-9 | RNA/DNA Polymerase Inhibitors
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Description: Non-nucleoside reverse transcriptase inhibitor

Chemical Name: 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile

Purity: ≥98%

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Biological Activity

Rilpivirine is a potent diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). It has high antiviral activity against wild-type HIV-1 and mutant viruses (EC50 values are 0.4 and 0.1-2.0 nM, respectively in a cell-based assay). This compound is orally bioavailable.

Technical Data

M.Wt:
366.42
Formula:
C22H18N6
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
500287-72-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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