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Remodelin

Catalog #: 5193 Datasheet
Catalog # Availability Size / Price Qty
5193/50
5193/10
Remodelin | CAS No. 949912-58-7 | Other Transferase Inhibitors
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Description: N-acetyltransferase 10 (NAT10) inhibitor

Chemical Name: 4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile

Purity: ≥99%

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Remodelin is a N-acetyltransferase 10 (NAT10) inhibitor. Improves nuclear shape in HGPS (Hutchinson-Gilford progeria syndrome) cells and lamin A/C depleted cells.

Technical Data

M.Wt:
282.36
Formula:
C15H14N4S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
949912-58-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Chemical inhibition of NAT10 corrects defects of laminopathic cells.
    Larrieu et al.
    Science, 2014;344:527

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