Recombinant Mouse FGF basic/FGF2/bFGF Protein Summary
Product Specifications
Ala11-Ser154
Analysis
Product Datasheets
3139-FB (with carrier)
3139-FB/CF (carrier free)
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
3139-FB
Formulation | Lyophilized from a 0.2 μm filtered solution in MOPS, Na2SO4, EDTA and DTT with BSA as a carrier protein. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
3139-FB/CF
Formulation | Lyophilized from a 0.2 μm filtered solution in MOPS, Na2SO4, EDTA and DTT. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Scientific Data
Recombinant Mouse FGF basic/FGF2/bFGF (Catalog # 3139-FB) stimulates cell proliferation of the NR6R‑3T3 mouse fibroblast cell line. The ED50 for this effect is 0.3-1.8 ng/mL.
1 μg/lane of Recombinant Mouse FGF basic/FGF2/bFGF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 18 kDa.
Background: FGF basic/FGF2/bFGF
FGF basic (FGF-2, HBGF-2) is one of at least 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation (1-3). Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. Storage pools within the cell or on cell surface heparan sulfate proteoglycans (HSPG) are likely. The predicted 17 kDa FGF basic isoform can be located in both the cytoplasm and the nucleus and is presumed to be the form secreted (4). Transcription from alternate start sites produces 21-24 kDa forms found only in the nucleus. High and low molecular weight human FGF basic targets the expression of different genes when expressed in NIH-3T3 cells (5). The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine and sheep FGF basic (6, 7). Autocrine, intracrine and paracrine actions of FGF basic have been identified. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysaccharides and lipids with lower affinity (3). Expression of FGF basic is nearly ubiquitous but disruption of the mouse FGF basic gene gives a relatively mild phenotype, suggesting compensation by other FGF family members. FGF basic modulates such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, neuronal function and neural degeneration. Transgenic overexpression of FGF basic results in excessive proliferation and angiogenesis reminiscent of a variety of pathological conditions (1-3).
- Coulier, F. et al. (1997) J. Mol. Evol. 44:43.
- Fernig, D. et al. (1994) Prog. Growth Factor Res. 5:353.
- Presta, M. et al. (2005) Cytokine. Growth Factor Rev. 16:159.
- Claus, P. et al. (2003) J. Biol. Chem. 278:479.
- Quarto, N. et al. (2005) Gene 356:49.
- Tsuneto, M. et al. (2005) Biochem. Biophys. Res. Comm. 335:1239.
- Hebert, J. M. et al. (1990) Dev. Biol. 138:454.
Citations for Recombinant Mouse FGF basic/FGF2/bFGF Protein
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Single nuclei transcriptomics reveal the differentiation trajectories of periosteal skeletal/stem progenitor cells in bone regeneration
Authors: Perrin, S;Ethel, M;Bretegnier, V;Goachet, C;Wotawa, CA;Luka, M;Coulpier, F;Masson, C;Ménager, M;Colnot, C;
bioRxiv : the preprint server for biology
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Auts2 enhances neurogenesis and promotes expansion of the cerebral cortex
Authors: Boucherie, C;Alkailani, M;Jossin, Y;Ruiz-Reig, N;Mahdi, A;Aldaalis, A;Aittaleb, M;Tissir, F;
Journal of advanced research
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Metabolic memory of ?9-tetrahydrocannabinol exposure in pluripotent stem cells and primordial germ cells-like cells
Authors: Verdikt, R;Armstrong, AA;Cheng, J;Hwang, YS;Clark, AT;Yang, X;Allard, P;
eLife
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Suppression of angiopoietin-like 4 reprograms endothelial cell metabolism and inhibits angiogenesis
Authors: Chaube, B;Citrin, KM;Sahraei, M;Singh, AK;de Urturi, DS;Ding, W;Pierce, RW;Raaisa, R;Cardone, R;Kibbey, R;Fernández-Hernando, C;Suárez, Y;
Nature communications
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The L27 Domain of MPP7 enhances TAZ-YY1 Cooperation to Renew Muscle Stem Cells
Authors: Shao, A;Kissil, JL;Fan, CM;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
The Impact of Biomaterial Surface Properties on Engineering Neural Tissue for Spinal Cord Regeneration
Authors: da Silva, VA;Bobotis, BC;Correia, FF;Lima-Vasconcellos, TH;Chiarantin, GMD;De La Vega, L;Lombello, CB;Willerth, SM;Malmonge, SM;Paschon, V;Kihara, AH;
International journal of molecular sciences
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition
Authors: Zeng, C;Chen, J;Cooke, EW;Subuddhi, A;Roodman, ET;Chen, FX;Cao, K;
Nature communications
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition
Authors: Zeng, C;Chen, J;Cooke, EW;Subuddhi, A;Roodman, ET;Chen, FX;Cao, K;
Nature communications
Species: Mouse
Sample Types: Embryoid Bodies
Applications: Bioassay -
EZH2 inhibition promotes tumor immunogenicity in lung squamous cell carcinomas
Authors: DuCote, TJ;Song, X;Naughton, KJ;Chen, F;Plaugher, DR;Childress, AR;Edgin, AR;Qu, X;Liu, J;Liu, J;Li, F;Wong, KK;Brainson, CF;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Organoid
Applications: Bioassay -
A ligation-independent sequencing method reveals tRNA-derived RNAs with blocked 3' termini
Authors: Scacchetti, A;Shields, EJ;Trigg, NA;Wilusz, JE;Conine, CC;Bonasio, R;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Identification of age-specific gene regulators of La Crosse virus neuroinvasion and pathogenesis
Authors: Basu, R;Ganesan, S;Winkler, CW;Anzick, SL;Martens, C;Peterson, KE;Fraser, IDC;
Nature communications
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Cholesterol biosynthesis modulates differentiation in murine cranial neural crest cells
Authors: Pascual, F;Icyuz, M;Karmaus, P;Brooks, A;Van Gorder, E;Fessler, MB;Shaw, ND;
Scientific reports
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
YY1 lactylation in microglia promotes angiogenesis through transcription activation-mediated upregulation of FGF2
Authors: X Wang, W Fan, N Li, Y Ma, M Yao, G Wang, S He, W Li, J Tan, Q Lu, S Hou
Genome Biology, 2023-04-21;24(1):87.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay -
Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory components
Authors: E Ugur, A de la Port, W Qin, S Bultmann, A Ivanova, M Drukker, M Mann, M Wierer, H Leonhardt
Nucleic Acids Research, 2023-04-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma
Authors: V Davalos, CD Lovell, R Von Itter, I Dolgalev, P Agrawal, G Baptiste, DJ Kahler, E Sokolova, S Moran, L Piqué, E Vega-Saenz, B Fontanals-, A Karz, A Tsirigos, C Yun, F Darvishian, HC Etchevers, I Osman, M Esteller, M Schober, E Hernando
Nature Communications, 2023-04-04;14(1):1867.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5
Authors: EB Choi, M Vodnala, P Saini, S Anugula, M Zerbato, JJ Ho, J Wang, SJ Ho Sui, J Yoon, M Roels, C Inouye, YW Fong
The Journal of Biological Chemistry, 2023-02-09;0(0):102996.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Posttreatment with dexmedetomidine aggravates LPS-induced myocardial dysfunction partly via activating cardiac endothelial alpha2A-AR in mice
Authors: X Tang, C Zhang, T Tian, X Dai, Y Xing, Y Wang, D Yang, H Li, Y Wang, X Lv, H Wang
International immunopharmacology, 2023-01-23;116(0):109724.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Unconventional secretion of alpha-synuclein mediated by palmitoylated DNAJC5 oligomers
Authors: S Wu, NC Hernandez, DW Sirkis, I Thomas-Wri, R Wade-Marti, R Schekman
Elife, 2023-01-10;12(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression
Authors: A Gravina, G Tediashvil, R Rajalingam, Z Quandt, C Deisenroth, S Schrepfer, T Deuse
Nature Biotechnology, 2023-01-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke
Authors: X Hong, Y Jian, S Ding, J Zhou, X Zheng, H Zhang, B Zhou, C Zhuang, J Wan, X Tong
EBioMedicine, 2022-12-15;87(0):104406.
Species: Mouse
Sample Types: Organoid
Applications: Bioassay -
PEAR1 regulates expansion of activated fibroblasts and deposition of extracellular matrix in pulmonary fibrosis
Authors: Y Geng, L Li, J Yan, K Liu, A Yang, L Zhang, Y Shen, H Gao, X Wu, I Noth, Y Huang, J Liu, X Fan
Nature Communications, 2022-11-19;13(1):7114.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819
Authors: LP Fernandes, R Enriquez-G, PA Gould, JH Holt, L Conde, G Ecco, J Herrero, R Gifford, D Trono, G Kassiotis, HM Rowe
Science Advances, 2022-10-28;8(43):eabp8085.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Loss of full-length dystrophin expression results in major cell-autonomous abnormalities in proliferating myoblasts
Authors: MRF Gosselin, V Mournetas, M Borczyk, S Verma, A Occhipinti, J Róg, L Bozycki, M Korostynsk, SC Robson, C Angione, C Pinset, DC Gorecki
Elife, 2022-09-27;11(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Pluripotency factors regulate the onset of Hox cluster activation in the early embryo
Authors: M Tiana, E Lopez-Jime, JS de Aja, A Barral, J Victorino, C Badia-Care, I Rollan, R Rouco, E Santos, H Sanchez-Ir, RD Acemel, C Torroja, J Adan, E Andres-Leo, JL Gomez-Skar, G Giovinazzo, F Sanchez-Ca, M Manzanares
Oncogene, 2022-07-15;8(28):eabo3583.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
3D culturing of human pluripotent stem cells-derived endothelial cells for vascular regeneration
Authors: E Gara, E Zucchelli, A Nemes, Z Jakus, K Ajtay, É Kemecsei, G Kiszler, N Heged?s, K Szigeti, I Földes, K Árvai, J Kósa, K Kolev, E Komorowicz, P Padmanabha, P Maurovich-, E Dósa, G Várady, M Pólos, I Hartyánszk, SE Harding, B Merkely, D Máthé, G Szabó, T Radovits, G Földes
Theranostics, 2022-06-06;12(10):4684-4702.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Towards 3D Bioprinted Spinal Cord Organoids
Authors: Y Han, M King, E Tikhomirov, P Barasa, CDS Souza, J Lindh, D Baltriukie, L Ferraiuolo, M Azzouz, MR Gullo, EN Kozlova
International Journal of Molecular Sciences, 2022-05-21;23(10):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Progenitor cells from brown adipose tissue undergo neurogenic differentiation
Authors: M Jumabay, L Zhang, J Yao, KI Boström
Scientific Reports, 2022-04-04;12(1):5614.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Ultraefficient extracellular vesicle-guided direct reprogramming of fibroblasts into functional cardiomyocytes
Authors: H Kim, BW Song, SJ Park, SW Choi, H Moon, KC Hwang, SW Kang, SH Moon, Y Yang, IC Kwon, SH Kim
Science Advances, 2022-02-25;8(8):eabj6621.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
MGP Regulates Perivascular Adipose-Derived Stem Cells Differentiation Toward Smooth Muscle Cells Via BMP2/SMAD Pathway Enhancing Neointimal Formation
Authors: H Ni, C Liu, Y Chen, Y Lu, Y Ji, M Xiang, Y Xie
Cell Transplantation, 2022-01-01;31(0):9636897221075.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
ATM modulates subventricular zone neural stem cell maintenance and senescence through Notch signaling pathway
Authors: C Dong, X Wang, L Sun, L Zhu, D Yang, S Gao, W Zhang, B Ling, A Liang, Z Gao, J Xu
Stem Cell Research, 2021-12-07;58(0):102618.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The ETS transcription factor ERF controls the exit from the na�ve pluripotent state in a MAPK-dependent manner
Authors: M Vega-Sendi, T Olbrich, D Tillo, AD Tran, CN Domingo, M Franco, PC FitzGerald, MJ Kruhlak, S Ruiz
Science Advances, 2021-10-01;7(40):eabg8306.
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Examining the Developmental Trajectory of an in Vitro Model of Mouse Primordial Germ Cells following Exposure to Environmentally Relevant Bisphenol A Levels
Authors: SKT Ooi, H Jiang, Y Kang, P Allard
Environmental health perspectives, 2021-09-29;129(9):97013.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis
Authors: Y Wang, Y Zhu, Y Gu, M Ma, Y Wang, S Qi, Y Zeng, R Zhu, X Wang, P Yu, J Xu, Y Shu, FX Yu
Cell Reports, 2021-08-24;36(8):109596.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Derivation of Mouse Parthenogenetic Advanced Stem Cells
Authors: M Wei, J Zhang, J Liu, C Zhao, S Cao, X Yan, B Wu, S Bao
International Journal of Molecular Sciences, 2021-08-20;22(16):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Age influences susceptibility of brain capillary endothelial cells to La Crosse virus infection and cell death
Authors: R Basu, V Nair, CW Winkler, TA Woods, IDC Fraser, KE Peterson
Journal of Neuroinflammation, 2021-06-03;18(1):125.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue
Authors: N Joffin, VA Paschoal, CM Gliniak, C Crewe, A Elnwasany, LI Szweda, Q Zhang, C Hepler, CM Kusminski, R Gordillo, DY Oh, RK Gupta, PE Scherer
Cell Stem Cell, 2021-02-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Isolation of PRRX1-positive adult pituitary stem/progenitor cells from the marginal cell layer of the mouse anterior lobe
Authors: A Shintani, M Higuchi
Stem Cell Research, 2021-02-02;52(0):102223.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Generation of High-Yield, Functional Oligodendrocytes from a c-myc Immortalized Neural Cell Line, Endowed with Staminal Properties
Authors: MG Reccia, F Volpicelli, E Benedikz, ÅF Svenningse, L Colucci-D'
International Journal of Molecular Sciences, 2021-01-23;22(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Greater epithelial ridge cells are the principal organoid-forming progenitors of the mouse cochlea
Authors: M Kubota, M Scheibinge, TA Jan, S Heller
Cell Reports, 2021-01-19;34(3):108646.
Species: Mouse
Sample Types: Organoid
Applications: Bioassay -
SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1&alpha and reactive oxygen species
Authors: Z Yang, Y Huang, L Zhu, K Yang, K Liang, J Tan, B Yu
Cell Death & Disease, 2021-01-12;12(1):77.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Inhibition of Gli2 suppresses tumorigenicity in glioblastoma stem cells derived from a de novo murine brain cancer model
Authors: S Tanigawa, M Fujita, C Moyama, S Ando, H Ii, Y Kojima, T Fujishita, M Aoki, H Takeuchi, T Yamanaka, Y Takahashi, N Hashimoto, S Nakata
Cancer Gene Therapy, 2021-01-07;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice
Authors: C Zhou, H Chen, JF Zheng, ZD Guo, ZJ Huang, Y Wu, JJ Zhong, XC Sun, CJ Cheng
Neural Regen Res, 2020-12-01;15(12):2318-2326.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS
Authors: MF Leyton-Jai, P Ivert, J Hoeber, Y Han, A Feiler, C Zhou, S Pankratova, V Shoshan-Ba, A Israelson, EN Kozlova
Sci Rep, 2020-11-26;10(1):20675.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
TRF2-independent chromosome end protection during pluripotency
Authors: P Ruis, D Van Ly, V Borel, GR Kafer, A McCarthy, S Howell, R Blassberg, AP Snijders, J Briscoe, KK Niakan, P Marzec, AJ Cesare, SJ Boulton
Nature, 2020-11-25;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
Authors: CB Mulholland, A Nishiyama, J Ryan, R Nakamura, M Yi?it, IM Glück, C Trummer, W Qin, MD Bartoschek, FR Traube, E Parsa, E Ugur, M Modic, A Acharya, P Stolz, C Ziegenhain, M Wierer, W Enard, T Carell, DC Lamb, H Takeda, M Nakanishi, S Bultmann, H Leonhardt
Nature Communications, 2020-11-24;11(1):5972.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
Authors: KC Allan, LR Hu, MA Scavuzzo, AR Morton, AS Gevorgyan, EF Cohn, BLL Clayton, IR Bederman, S Hung, CF Bartels, M Madhavan, PJ Tesar
Cell Stem Cell, 2020-10-21;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes
Authors: R Shukla, HK Mjoseng, JP Thomson, S Kling, D Sproul, DS Dunican, B Ramsahoye, T Wongtawan, F Treindl, MF Templin, IR Adams, S Pennings, RR Meehan
Nucleic Acids Res., 2020-08-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Protein Kinase CK2 Regulates Nerve/Glial Antigen (NG)2-Mediated Angiogenic Activity of Human Pericytes
Authors: BM Schmitt, AS Boewe, V Becker, L Nalbach, Y Gu, C Götz, MD Menger, MW Laschke, E Ampofo
Cells, 2020-06-25;9(6):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts
Authors: D Xiao, Q Deng, Y Guo, X Huang, M Zou, J Zhong, P Rao, Z Xu, Y Liu, Y Hu, Y Shen, K Jin, M Xiang
Sci Adv, 2020-05-29;6(22):eaaz5858.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation
Authors: JM Kim, YS Yang, KH Park, X Ge, R Xu, N Li, M Song, H Chun, S Bok, JF Charles, O Filhol-Coc, B Boldyreff, T Dinter, PB Yu, N Kon, W Gu, T Takarada, MB Greenblatt, JH Shim
Nat Commun, 2020-05-08;11(1):2289.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The translational landscape of ground state pluripotency
Authors: Y Atlasi, SM Jafarnejad, CG Gkogkas, M Vermeulen, N Sonenberg, HG Stunnenber
Nat Commun, 2020-04-01;11(1):1617.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy
Authors: K Ichikawa, S Watanabe M, Y Minoshima, J Matsui, Y Funahashi
Sci Rep, 2020-02-19;10(1):2939.
Species: Mouse
Sample Types: Whole Cells
Applications: IP -
Effects of Gintonin-Enriched Fraction on Methylmercury-Induced Neurotoxicity and Organ Methylmercury Elimination
Authors: HJ Kim, SH Choi, NE Lee, HJ Cho, H Rhim, HC Kim, SH Hwang, SY Nah
Int J Environ Res Public Health, 2020-01-29;17(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
CTNNB1/&beta-catenin dysfunction contributes to adiposity by regulating the cross-talk of mature adipocytes and preadipocytes
Authors: M Chen, P Lu, Q Ma, Y Cao, N Chen, W Li, S Zhao, B Chen, J Shi, Y Sun, H Shen, L Sun, J Shen, Q Liao, Y Zhang, J Hong, W Gu, R Liu, G Ning, W Wang, J Wang
Sci Adv, 2020-01-08;6(2):eaax9605.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Deletion of tetraspanin CD151 alters the Wnt oncogene-induced mammary tumorigenesis: A cell type-linked function and signaling
Authors: H Li, J Li, R Han, X Deng, J Shi, H Huang, N Hamad, A McCaughley, J Liu, C Wang, K Chen, D Wei, J Qiang, S Thatcher, Y Wu, C Liu, O Thibault, X Wei, S Chen, H Qian, BP Zhou, P Xu, XH Yang
Neoplasia, 2019-11-26;21(12):1151-1163.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Reprogramming of Fibroblasts to Oligodendrocyte Progenitor-like Cells Using CRISPR/Cas9-Based Synthetic Transcription Factors
Authors: M Matjusaiti, LJ Wagstaff, A Martella, B Baranowski, C Blin, S Gogolok, A Williams, SM Pollard
Stem Cell Reports, 2019-11-07;13(6):1053-1067.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
The panniculus carnosus muscle: A novel model of striated muscle regeneration that exhibits sex differences in the mdx mouse
Authors: OA Bahri, N Naldaiz-Ga, DC Kennedy, AM Wheatley, A Izeta, KJA McCullagh
Sci Rep, 2019-11-04;9(1):15964.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Tox4 modulates cell fate reprogramming
Authors: L Vanheer, J Song, N De Geest, A Janiszewsk, I Talon, C Provenzano, T Oh, J Chappell, V Pasque
J. Cell. Sci., 2019-10-22;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1
Authors: Y Rong, W Liu, C Lv, J Wang, Y Luo, D Jiang, L Li, Z Zhou, W Zhou, Q Li, G Yin, L Yu, J Fan, W Cai
Aging (Albany NY), 2019-09-28;11(18):7723-7745.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Ciliary IFT80 regulates dental pulp stem cells differentiation by FGF/FGFR1 and Hh/BMP2 signaling
Authors: X Yuan, M Liu, X Cao, S Yang
Int. J. Biol. Sci., 2019-08-06;15(10):2087-2099.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Pre-clinical development of U3-1784, a novel FGFR4 antibody against cancer, and avoidance of its on-target toxicity
Authors: R Bartz, K Fukuchi, T Ohtsuka, T Lange, K Gruner, I Watanabe, S Hayashi, Y Oda, R Kawaida, H Komori, Y Kashimoto, P Wirtz, JA Mayer, M Redondo-Mü, S Saito, M Takahashi, H Hanzawa, E Imai, A Martinez, M Hanai, D Häussinger, RW Chapman, T Agatsuma, J Bange, R Abraham
Mol. Cancer Ther., 2019-07-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Differentiation Induction as a Response to Irradiation in Neural Stem Cells In Vitro
Authors: J Koní?ová, L Cupal, Š Jarošová, A Michaelide, J Vachelová, M Davídková, P Bart?n?k, M Zíková
Cancers (Basel), 2019-06-29;11(7):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture -
Mitochondrial Complex I Function Is Essential for Neural Stem/Progenitor Cells Proliferation and Differentiation
Authors: D Cabello-Ri, H Sarmiento-, J López-Barn, AM Muñoz-Cabe
Front Neurosci, 2019-06-26;13(0):664.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Early Seizure Activity Accelerates Depletion of Hippocampal Neural Stem Cells and Impairs Spatial Discrimination in an Alzheimer's Disease Model
Authors: CH Fu, DM Iascone, I Petrof, A Hazra, X Zhang, MS Pyfer, U Tosi, BF Corbett, J Cai, J Lee, J Park, L Iacovitti, HE Scharfman, G Enikolopov, J Chin
Cell Rep, 2019-06-25;27(13):3741-3751.e4.
Species: Mouse, Transgenic Mouse
Sample Types: Spheroid
Applications: Bioassay -
CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties
Authors: SS Joshi, B Tandukar, L Pan, JM Huang, F Livak, BJ Smith, T Hodges, AA Mahurkar, TJ Hornyak
PLoS Genet., 2019-04-24;15(4):e1008034.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy
Authors: Y Rong, W Liu, J Wang, J Fan, Y Luo, L Li, F Kong, J Chen, P Tang, W Cai
Cell Death Dis, 2019-04-18;10(5):340.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Inhibition of miRNA-27b enhances neurogenesis via AMPK activation in a mouse ischemic stroke model
Authors: Z Wang, Y Yuan, Z Zhang, K Ding
FEBS Open Bio, 2019-04-11;9(5):859-869.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Maternal hyperglycemia disturbs neocortical neurogenesis via epigenetic regulation in C57BL/6J mice
Authors: S Ji, W Zhou, X Li, S Liu, F Wang, X Li, T Zhao, G Ji, J Du, A Hao
Cell Death Dis, 2019-03-01;10(3):211.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans
Authors: SL Taylor, J Hogwood, W Guo, EA Yates, JE Turnbull
Sci Rep, 2019-02-25;9(1):2679.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Distinct roles of Dlk1 isoforms in bi-potential differentiation of hepatic stem cells
Authors: J Huang, X Zhao, J Wang, Y Cheng, Q Wu, B Wang, F Zhao, L Meng, Y Zhang, M Jin, H Xu
Stem Cell Res Ther, 2019-01-15;10(1):31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin
Authors: N Boukelmoun, GS Chiu, A Kavelaars, CJ Heijnen
Acta Neuropathol Commun, 2018-12-12;6(1):139.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Klf5 suppresses ERK signaling in mouse pluripotent stem cells
Authors: T Azami, K Matsumoto, H Jeon, T Waku, M Muratani, H Niwa, S Takahashi, M Ema
PLoS ONE, 2018-11-19;13(11):e0207321.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression
Authors: MN Lee, HS Hwang, SH Oh, A Roshanzade, JW Kim, JH Song, ES Kim, JT Koh
Exp. Mol. Med., 2018-11-05;50(11):142.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis
Authors: G Wolff, AE Taranko, I Meln, J Weinmann, T Sijmonsma, S Lerch, D Heide, AT Billeter, D Tews, D Krunic, P Fischer-Po, BP Müller-Sti, S Herzig, D Grimm, M Heikenwäld, WW Kao, A Vegiopoulo
Mol Metab, 2018-10-23;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Analyzing bovine OCT4 and NANOG enhancer activity in pluripotent stem cells using fluorescent protein reporters
Authors: D Huang, L Wang, NC Talbot, C Huang, L Pu, X Zhao, X Tian, M Zhang, Y Tang
PLoS ONE, 2018-10-05;13(10):e0203923.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Neuroglobin promotes neurogenesis through Wnt signaling pathway
Authors: Z Yu, C Cheng, Y Liu, N Liu, EH Lo, X Wang
Cell Death Dis, 2018-09-20;9(10):945.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
Authors: AM Lager, OG Corradin, JM Cregg, MS Elitt, HE Shick, BLL Clayton, KC Allan, HE Olsen, M Madhavan, PJ Tesar
Nat Commun, 2018-09-13;9(1):3708.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Groucho related gene 5 (GRG5) is involved in embryonic and neural stem cell state decisions
Authors: K Chanoumido, C Hadjimicha, P Athanasoul, H Ahlenius, A Klonizakis, C Nikolaou, E Drakos, A Kostouros, I Stratidaki, M Grigoriou, A Kretsovali
Sci Rep, 2018-09-13;8(1):13790.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
MicroRNA-532-5p Regulates Pericyte Function by Targeting the Transcription Regulator BACH1 and Angiopoietin-1
Authors: SC Slater, E Jover, A Martello, T Miti?, I Rodriguez-, R Vono, VV Alvino, SC Satchell, G Spinetti, A Caporali, P Madeddu
Mol. Ther., 2018-09-01;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
d4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors
Authors: I Bayindir-B, G Wolff, S Lerch, T Sijmonsma, M Schuster, J Gronych, AT Billeter, R Babaei, D Krunic, L Ketscher, N Spielmann, M Hrabe de A, JL Ruas, BP Müller-Sti, M Heikenwald, P Lichter, S Herzig, A Vegiopoulo
EMBO Mol Med, 2018-08-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo
Authors: A Spangler, EY Su, AM Craft, P Cahan
Stem Cell Res, 2018-07-29;31(0):201-215.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
mTORC1 accelerates retinal development via the immunoproteasome
Authors: JH Choi, HS Jo, S Lim, HT Kim, KW Lee, KH Moon, T Ha, SS Kwak, Y Kim, EJ Lee, CO Joe, JW Kim
Nat Commun, 2018-06-27;9(1):2502.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells
Authors: SK Tasian, JA Casas, D Posocco, S Gandre-Bab, AL Gagne, G Liang, ML Loh, MJ Weiss, DL French, ST Chou
Leukemia, 2018-06-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
Authors: RP Russell, Y Fu, Y Liu, P Maye
Stem Cell Res, 2018-05-22;30(0):85-95.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development
Authors: Y Xiao, MC Hill, M Zhang, TJ Martin, Y Morikawa, S Wang, AR Moise, JD Wythe, JF Martin
Dev. Cell, 2018-04-23;45(2):153-169.e6.
Species: Mouse
Sample Types: Tissue Lysates
Applications: Cell Culture -
Loss of Stemness, EMT, and Supernumerary Tooth Formation in Cebpb-/-Runx2+/-Murine Incisors
Authors: K Saito, K Takahashi, B Huang, M Asahara, H Kiso, Y Togo, H Tsukamoto, S Mishima, M Nagata, M Iida, Y Tokita, M Asai, A Shimizu, T Komori, H Harada, M MacDougall, M Sugai, K Bessho
Sci Rep, 2018-03-26;8(1):5169.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Degradation of the endoplasmic reticulum-anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7in a manner dependent on the kinase GSK-3
Authors: S Nakayama, K Yumimoto, A Kawamura, KI Nakayama
J. Biol. Chem., 2018-02-22;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PPAR? modulation rescues mitochondrial fatty acid oxidation defects in the mdx model of muscular dystrophy
Authors: EL Bell, RW Shine, P Dwyer, L Olson, J Truong, R Fredenburg, M Goddeeris, D Stickens, E Tozzo
Mitochondrion, 2018-02-16;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene
Authors: XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, C Xu, Y Li, D Vershkov, A Cacace, RA Young, R Jaenisch
Cell, 2018-02-15;172(5):979-992.e6.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Zika virus infected primary microglia impairs NPCs proliferation and differentiation
Authors: J Wang, J Liu, R Zhou, X Ding, Q Zhang, C Zhang, L Li
Biochem. Biophys. Res. Commun., 2018-02-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
NADsupplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
Authors: Y Hou, S Lautrup, S Cordonnier, Y Wang, DL Croteau, E Zavala, Y Zhang, K Moritoh, JF O'Connell, BA Baptiste, TV Stevnsner, MP Mattson, VA Bohr
Proc. Natl. Acad. Sci. U.S.A., 2018-02-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Lysophosphatidic Acid Acyltransferase 3 Incorporates Docosahexaeneoic Acid into Skeletal Muscle Cell Membranes and Is Upregulated by PPAR? Activation
Authors: WJ Valentine, SM Tokuoka, D Hishikawa, Y Kita, H Shindou, T Shimizu
J. Lipid Res., 2017-12-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Generation of iPSC-derived limb progenitor-like cells for stimulating phalange regeneration in the adult mouse
Authors: Y Chen, H Xu, G Lin
Cell Discov, 2017-12-19;3(0):17046.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Derivation of hypermethylated pluripotent embryonic stem cells with high potency
Authors: S Bao, WW Tang, B Wu, S Kim, J Li, L Li, T Kobayashi, C Lee, Y Chen, M Wei, S Li, S Dietmann, F Tang, X Li, MA Surani
Cell Res., 2017-10-27;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Induced haploinsufficiency of Kit receptor tyrosine kinase impairs brain development
Authors: H Aoki, A Hara, T Kunisada
JCI Insight, 2017-10-05;2(19):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not na�ve ESCs
Authors: Y Shan, Z Liang, Q Xing, T Zhang, B Wang, S Tian, W Huang, Y Zhang, J Yao, Y Zhu, K Huang, Y Liu, X Wang, Q Chen, J Zhang, B Shang, S Li, X Shi, B Liao, C Zhang, K Lai, X Zhong, X Shu, J Wang, H Yao, J Chen, D Pei, G Pan
Nat Commun, 2017-09-22;8(1):672.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
IRX3 Promotes the Browning of White Adipocytes and Its Rare Variants are Associated with Human Obesity Risk
Authors: Y Zou, P Lu, J Shi, W Liu, M Yang, S Zhao, N Chen, M Chen, Y Sun, A Gao, Q Chen, Z Zhang, Q Ma, T Ning, X Ying, J Jin, X Deng, B Shen, Y Zhang, B Yuan, S Kauderer, S Liu, J Hong, R Liu, G Ning, W Wang, W Gu, J Wang
EBioMedicine, 2017-09-13;24(0):64-75.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Safflower Seed Oil, Containing Oleic Acid and Palmitic Acid, Enhances the Stemness of Cultured Embryonic Neural Stem Cells through Notch1 and Induces Neuronal Differentiation
Authors: M Ghareghani, K Zibara, H Azari, H Hejr, F Sadri, R Jannesar, G Ghalamfars, H Delaviz, E Nouri, A Ghanbari
Front Neurosci, 2017-08-03;11(0):446.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
DNA Methyltransferases Modulate Hepatogenic Lineage Plasticity of�Mesenchymal Stromal Cells
Authors: CW Lee, WC Huang, HD Huang, YH Huang, JH Ho, MH Yang, VW Yang, OK Lee
Stem Cell Reports, 2017-06-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
FGF23/FGFR4-mediated left ventricular hypertrophy is reversible
Authors: A Grabner, K Schramm, N Silswal, M Hendrix, C Yanucil, B Czaya, S Singh, M Wolf, S Hermann, J Stypmann, GS Di Marco, M Brand, MJ Wacker, C Faul
Sci Rep, 2017-05-16;7(1):1993.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
MicroRNA-27a reduces mutant hutingtin aggregation in an in vitro model of Huntington's disease
Authors: JJ Ban, JY Chung, M Lee, W Im, M Kim
Biochem. Biophys. Res. Commun., 2017-05-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation
Authors: O Bernatik, T Radaszkiew, M Behal, Z Dave, F Witte, A Mahl, NH Cernohorsk, P Krejci, S Stricker, V Bryja
Front Cell Dev Biol, 2017-05-04;5(0):47.
Species: Mouse, Rat
Sample Types: Whole Cells
Applications: Bioassay -
Transplantation of inhibitory precursor cells from medial ganglionic eminence produces distinct responses in two different models of acute seizure induction
Authors: DS Paiva, SAA Romariz, MF Valente, LB Moraes, L Covolan, ME Calcagnott, B Monteiro L
Epilepsy Behav, 2017-04-17;70(0):125-130.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Lacking of palladin leads to multiple cellular events changes which contribute to NTD
Authors: J Tan, XJ Chen, CL Shen, HX Zhang, LY Tang, SY Lu, WT Wu, Y Kuang, J Fei, ZG Wang
Neural Dev, 2017-03-24;12(1):4.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Substance P accelerates wound healing in type 2 diabetic mice through endothelial progenitor cell mobilization and Yes-associated protein activation
Authors: J Um, J Yu, KS Park
Mol Med Rep, 2017-03-21;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways
Authors: F Lacour, E Vezin, CF Bentzinger, MC Sincennes, L Giordani, A Ferry, R Mitchell, K Patel, MA Rudnicki, MC Chaboissie, AA Chassot, F Le Grand
Cell Rep, 2017-03-07;18(10):2320-2330.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts
Authors: L Leiss, E Mutlu, A Øyan, T Yan, O Tsinkalovs, L Sleire, K Petersen, MA Rahman, M Johannesse, SS Mitra, HK Jacobsen, KM Talasila, H Miletic, I Jonassen, X Li, NH Brons, KH Kalland, J Wang, PØ Enger
BMC Cancer, 2017-02-07;17(1):108.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Interplay between CCR7 and Notch1 axes promotes stemness in MMTV-PyMT mammary cancer cells
Authors: ST Boyle, KA Gieniec, CE Gregor, JW Faulkner, SR McColl, M Kochetkova
Mol. Cancer, 2017-01-31;16(1):19.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Direct induction of neural progenitor cells transiently passes through a partially reprogrammed state
Authors: Rui Gao
Biomaterials, 2016-12-10;119(0):53-67.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Transformation of jaw muscle satellite cells to cardiomyocytes
Authors: Randall S Daughters
Differentiation, 2016-12-03;93(0):58-65.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury
Authors: Benjamin Deneen
J. Neurosci., 2016-11-23;36(47):11904-11917.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease
Sci Rep, 2016-11-18;6(0):37443.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors
Nat Commun, 2016-11-16;7(0):13509.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Measuring Cell Viscoelastic Properties Using a Microfluidic Extensional Flow Device
Authors: Sanjay Kumar
Biophys. J., 2016-11-01;111(9):2039-2050.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A robust vitronectin-derived peptide for the scalable long-term expansion and neuronal differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (hNPCs)
Authors: Divya Varun
Acta Biomater, 2016-10-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Bmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro
PLoS ONE, 2016-10-18;11(10):e0164579.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module
Nat Commun, 2016-07-22;7(0):12277.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice
Authors: M Rozo, L Li, CM Fan
Nat. Med, 2016-07-04;22(8):889-96.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells
Elife, 2016-06-28;5(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Glipizide suppresses prostate cancer progression in the TRAMP model by inhibiting angiogenesis
Authors: Cuiling Qi
Sci Rep, 2016-06-13;6(0):27819.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Proangiogenic Interactions of Vascular Endothelial MMP14 With VEGF Receptor 1 in VEGFA-Mediated Corneal Angiogenesis.
Authors: Kyu-Yeon Han, Jin-Hong Chang, Hyun Lee, Dimitri T Azar
Investigative Ophthalmology & Visual Science, 2016-06-01;0(0):1552-5783.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors
Authors: Eva Hedlund
Sci Rep, 2016-06-01;6(0):26448.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus
Authors: Joon W Shim
Sci Rep, 2016-05-31;6(0):26794.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation
Sci Rep, 2016-05-24;6(0):26562.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Sequential Differentiation of Embryonic Stem Cells into Neural Epithelial-Like Stem Cells and Oligodendrocyte Progenitor Cells
PLoS ONE, 2016-05-18;11(5):e0155227.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles
Proc Natl Acad Sci USA, 2016-05-02;113(20):5552-7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Remission for Loss of Odontogenic Potential in a New Micromilieu In Vitro
Authors: Y Zheng, J Cai, AP Hutchins, L Jia, P Liu, D Yang, S Chen, L Ge, D Pei, S Wei
PLoS ONE, 2016-04-06;11(4):e0152893.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Myosin heavy chain is stabilized by BCL-2 interacting cell death suppressor (BIS) in skeletal muscle
Authors: J Hong, JS Park, H Lee, J Jeong, H Hyeon Yun, H Yun Kim, YG Ko, JH Lee
Exp Mol Med, 2016-04-01;48(0):e225.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
The PD-1/B7-H1 pathway modulates the natural killer cells versus mouse glioma stem cells.
Authors: Huang B, Zhan Y, Zong W, Yu C, Li J, Qu Y, Han S
PLoS ONE, 2015-08-12;10(8):e0134715.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Monocyte Chemoattractant Protein-Induced Protein 1 (MCPIP1) Enhances Angiogenic and Cardiomyogenic Potential of Murine Bone Marrow-Derived Mesenchymal Stem Cells.
Authors: Labedz-Maslowska A, Lipert B, Berdecka D, Kedracka-Krok S, Jankowska U, Kamycka E, Sekula M, Madeja Z, Dawn B, Jura J, Zuba-Surma E
PLoS ONE, 2015-07-27;10(7):e0133746.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline.
Authors: Chan W, Howe K, Clegg J, Guimond S, Price D, Turnbull J, Pratt T
PLoS ONE, 2015-06-15;10(6):e0130147.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Generation of Dopamine Neurons from Rodent Fibroblasts through the Expandable Neural Precursor Cell Stage.
Authors: Lim M, Chang M, Kim S, Yi S, Suh-Kim H, Jung S, Kim M, Kim J, Lee Y, Lee S, Kim D, Lee S, Park C
J Biol Chem, 2015-05-28;290(28):17401-14.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Periostin Promotes Neural Stem Cell Proliferation and Differentiation following Hypoxic-Ischemic Injury.
Authors: Ma S, Chen L, Lin Y, Yan H, Lv J, Xiong M, Li J, Cheng G, Yang Y, Qiu Z, Zhou W
PLoS ONE, 2015-04-20;10(4):e0123585.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Neuroprotective effects of oligodendrocyte progenitor cell transplantation in premature rat brain following hypoxic-ischemic injury.
Authors: Chen, Long-Xia, Ma, Si-Min, Zhang, Peng, Fan, Zi-Chuan, Xiong, Man, Cheng, Guo-Qian, Yang, Yi, Qiu, Zi-Long, Zhou, Wen-Hao, Li, Jin
PLoS ONE, 2015-03-19;10(3):e0115997.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through CD47 receptor protein.
Authors: Zheng Y, Zou F, Wang J, Yin G, Le V, Fei Z, Liu J
J Biol Chem, 2015-02-19;290(14):8975-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
TGFbeta signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions.
Authors: Shaw A, Pickup M, Chytil A, Aakre M, Owens P, Moses H, Novitskiy S
PLoS ONE, 2015-01-28;10(1):e0117908.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Signal transducer and activator of transcription-3 maintains the stemness of radial glia at mid-neurogenesis.
Authors: Hong S, Song M
J Neurosci, 2015-01-21;35(3):1011-23.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
Authors: Wang S, Amato K, Song W, Youngblood V, Lee K, Boothby M, Brantley-Sieders D, Chen J
Mol Cell Biol, 2015-01-12;35(7):1299-313.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Temporal expression of growth factors triggered by epiregulin regulates inflammation development.
Authors: Harada M, Kamimura D, Arima Y, Kohsaka H, Nakatsuji Y, Nishida M, Atsumi T, Meng J, Bando H, Singh R, Sabharwal L, Jiang J, Kumai N, Miyasaka N, Sakoda S, Yamauchi-Takihara K, Ogura H, Hirano T, Murakami M
J Immunol, 2015-01-02;194(3):1039-46.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Signaling via PI3K/FOXO1A pathway modulates formation and survival of human embryonic stem cell-derived endothelial cells.
Authors: Merkely B, Gara E, Lendvai Z, Skopal J, Leja T, Zhou W, Kosztin A, Varady G, Mioulane M, Bagyura Z, Nemeth T, Harding S, Foldes G
Stem Cells Dev, 2014-12-22;24(7):869-78.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Induction of primordial germ cell-like cells from mouse embryonic stem cells by ERK signal inhibition.
Authors: Kimura T, Kaga Y, Ohta H, Odamoto M, Sekita Y, Li K, Yamano N, Fujikawa K, Isotani A, Sasaki N, Toyoda M, Hayashi K, Okabe M, Shinohara T, Saitou M, Nakano T
Stem Cells, 2014-10-01;32(10):2668-78.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment.
Authors: Chen H, Wang S, Zhang J, Ren X, Zhang R, Shi W, Lv Y, Zhou Y, Yan X, Chen L, He L, Zhang B, Nan X, Yue W, Li Y, Pei X
Sci Rep, 2014-08-28;4(0):6222.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
Authors: Gouti, Mina, Tsakiridis, Anestis, Wymeersch, Filip J, Huang, Yali, Kleinjung, Jens, Wilson, Valerie, Briscoe, James
PLoS Biol, 2014-08-26;12(8):e1001937.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma.
Authors: Hu S, Rotschafer J, Lokensgard J, Cheeran M
PLoS ONE, 2014-08-18;9(8):e105219.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
T-cell TGF-beta signaling abrogation restricts medulloblastoma progression.
Authors: Gate D, Danielpour M, Rodriguez J, Kim G, Levy R, Bannykh S, Breunig J, Kaech S, Flavell R, Town T
Proc Natl Acad Sci U S A, 2014-07-31;111(33):E3458-66.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
In vivo and in vitro properties of STX2484: a novel non-steroidal anti-cancer compound active in taxane-resistant breast cancer.
Authors: Stengel C, Newman S, Day J, Chander S, Jourdan F, Leese M, Ferrandis E, Regis-Lydi S, Potter B, Reed M, Purohit A, Foster P
Br J Cancer, 2014-06-24;111(2):300-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency.
Authors: Onishi K, Tonge P, Nagy A, Zandstra P
Stem Cell Reports, 2014-06-06;3(1):156-68.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A Snail1/Notch1 signalling axis controls embryonic vascular development.
Authors: Wu Z, Rowe R, Lim K, Lin Y, Willis A, Tang Y, Li X, Nor J, Maillard I, Weiss S
Nat Commun, 2014-06-04;5(0):3998.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Functional cross-talk between the cellular prion protein and the neural cell adhesion molecule is critical for neuronal differentiation of neural stem/precursor cells.
Authors: Prodromidou K, Papastefanaki F, Sklaviadis T, Matsas R
Stem Cells, 2014-06-01;32(6):1674-87.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase.
Authors: Amand M, Erpicum C, Bajou K, Cerignoli F, Blacher S, Martin M, Dequiedt F, Drion P, Singh P, Zurashvili T, Vandereyken M, Musumeci L, Mustelin T, Moutschen M, Gilles C, Noel A, Rahmouni S
Mol Cancer, 2014-05-15;13(0):108.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.
Authors: Schrode N, Saiz N, Di Talia S, Hadjantonakis A
Dev Cell, 2014-05-15;29(4):454-67.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Nf2/Merlin controls spinal cord neural progenitor function in a Rac1/ErbB2-dependent manner.
Authors: Garcia C, Gutmann D
PLoS ONE, 2014-05-09;9(5):e97320.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Boundary cap neural crest stem cells homotopically implanted to the injured dorsal root transitional zone give rise to different types of neurons and glia in adult rodents.
Authors: Trolle, Carl, Konig, Niclas, Abrahamsson, Ninnie, Vasylovska, Svitlana, Kozlova, Elena N
BMC Neurosci, 2014-05-05;15(0):60.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A novel pro-angiogenic function for interferon-gamma-secreting natural killer cells.
Authors: Lee H, Schlereth S, Park E, Emami-Naeini P, Chauhan S, Dana R
Invest Ophthalmol Vis Sci, 2014-05-02;55(5):2885-92.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.
Authors: Chong J, Yang X, Don C, Minami E, Liu Y, Weyers J, Mahoney W, Van Biber B, Cook S, Palpant N, Gantz J, Fugate J, Muskheli V, Gough G, Vogel K, Astley C, Hotchkiss C, Baldessari A, Pabon L, Reinecke H, Gill E, Nelson V, Kiem H, Laflamme M, Murry C
Nature, 2014-04-30;510(7504):273-7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A modified EpiSC culture condition containing a GSK3 inhibitor can support germline-competent pluripotency in mice.
Authors: Tsukiyama, Tomoyuki, Ohinata, Yasuhide
PLoS ONE, 2014-04-15;9(4):e95329.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters.
Authors: Nobuhisa I, Osawa M, Uemura M, Kishikawa Y, Anani M, Harada K, Takagi H, Saito K, Kanai-Azuma M, Kanai Y, Iwama A, Taga T
Mol Cell Biol, 2014-03-24;34(11):1976-90.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Transcription factor-induced lineage programming of noradrenaline and motor neurons from embryonic stem cells.
Authors: Mong J, Panman L, Alekseenko Z, Kee N, Stanton L, Ericson J, Perlmann T
Stem Cells, 2014-03-01;32(3):609-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus promotes angiogenesis through targeting notch signaling effector Hey1.
Authors: Wang X, He Z, Xia T, Li X, Liang D, Lin X, Wen H, Lan K
Cancer Res, 2014-02-12;74(7):2026-37.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
A comparative study of protocols for mouse embryonic stem cell culturing.
Authors: Tamm C, Pijuan Galito S, Anneren C
PLoS ONE, 2013-12-10;8(12):e81156.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Frs2alpha and Shp2 signal independently of Gab to mediate FGF signaling in lens development.
Authors: Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins T, Wang F, Feng G, Gotoh N, Zhang X
J Cell Sci, 2013-11-27;127(0):571-82.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Generation of robust vascular networks from cardiovascular blast populations derived from human induced pluripotent stem cells in vivo and ex vivo organ culture system.
Authors: Kawamoto T, Kobayashi Y, Nakajima H, Yamagishi Y
Biochem Biophys Res Commun, 2013-10-16;441(1):180-5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor gamma (PPARgamma) in the conversion of white-to-brown adipocytes.
Authors: Garcia-Alonso V, Lopez-Vicario C, Titos E, Moran-Salvador E, Gonzalez-Periz A, Rius B, Parrizas M, Werz O, Arroyo V, Claria J
J Biol Chem, 2013-08-13;288(39):28230-42.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors.
Authors: Hunter, K E, Palermo, C, Kester, J C, Simpson, K, Li, J-P, Tang, L H, Klimstra, D S, Vlodavsky, I, Joyce, J A
Oncogene, 2013-05-06;33(14):1799-808.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.
Authors: Karwacki-Neisius V, Goke J, Osorno R, Halbritter F, Ng J, Weisse A, Wong F, Gagliardi A, Mullin N, Festuccia N, Colby D, Tomlinson S, Ng H, Chambers I
Cell Stem Cell, 2013-05-02;12(5):531-45.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Co-culture of neural crest stem cells (NCSC) and insulin producing beta-TC6 cells results in cadherin junctions and protection against cytokine-induced beta-cell death.
Authors: Ngamjariyawat A, Turpaev K, Vasylovska S, Kozlova E, Welsh N
PLoS ONE, 2013-04-17;8(4):e61828.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT.
Authors: Gomez-Ospina, Natalia, Panagiotakos, Georgia, Portmann, Thomas, Pasca, Sergiu P, Rabah, Dania, Budzillo, Agata, Kinet, Jean Pie, Dolmetsch, Ricardo
PLoS ONE, 2013-04-16;8(4):e60526.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.
Authors: Najm, Fadi J, Lager, Angela M, Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V, Factor, Daniel C, Karl, Robert T, Maeda, Tadao, Miller, Robert H, Tesar, Paul J
Nat Biotechnol, 2013-04-14;31(5):426-33.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis.
Authors: Zhang G, Panigrahy D, Mahakian L, Yang J, Liu J, Stephen Lee K, Wettersten H, Ulu A, Hu X, Tam S, Hwang S, Ingham E, Kieran M, Weiss R, Ferrara K, Hammock B
Proc Natl Acad Sci U S A, 2013-04-03;110(16):6530-5.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
MicroRNA-17-92 cluster mediates the proliferation and survival of neural progenitor cells after stroke.
Authors: Liu, Xian Shu, Chopp, Michael, Wang, Xin Li, Zhang, Li, Hozeska-Solgot, Ann, Tang, Tao, Kassis, Haifa, Zhang, Rui Lan, Chen, Charles, Xu, Jennifer, Zhang, Zheng Ga
J Biol Chem, 2013-03-19;288(18):12478-88.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification.
Authors: Hoffman J, Wu C, Merrill B
Development, 2013-03-13;140(8):1665-75.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319.
Authors: Kharitonenkov, Alexei, Beals, John M, Micanovic, Radmila, Strifler, Beth A, Rathnachalam, Radhakri, Wroblewski, Victor J, Li, Shun, Koester, Anja, Ford, Amy M, Coskun, Tamer, Dunbar, James D, Cheng, Christin, Frye, Christop, Bumol, Thomas F, Moller, David E
PLoS ONE, 2013-03-11;8(3):e58575.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Stimulation -
Role for compartmentalization in nephron progenitor differentiation.
Authors: Brown A, Muthukrishnan S, Guay J, Adams D, Schafer D, Fetting J, Oxburgh L
Proc Natl Acad Sci U S A, 2013-03-04;110(12):4640-5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism.
Authors: Itoh, Yasuhiro, Moriyama, Yasunobu, Hasegawa, Tsuyoshi, Endo, Takaho A, Toyoda, Tetsuro, Gotoh, Yukiko
Nat Neurosci, 2013-02-24;16(4):416-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation.
Authors: Tucker B, Anfinson K, Mullins R, Stone E, Young M
Stem Cells Transl Med, 2012-12-27;2(1):16-24.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The vitamin K-dependent anticoagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner.
Authors: Fraineau S, Monvoisin A, Clarhaut J, Talbot J, Simonneau C, Kanthou C, Kanse S, Philippe M, Benzakour O
Blood, 2012-10-12;120(25):5073-83.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay -
FGF23 induces left ventricular hypertrophy.
Authors: Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, Gutierrez OM, Aguillon-Prada R, Lincoln J, Hare JM, Mundel P, Morales A, Scialla J, Fischer M, Soliman EZ, Chen J, Go AS, Rosas SE, Nessel L, Townsend RR, Feldman HI, St John Sutton M, Ojo A, Gadegbeku C, Di Marco GS, Reuter S, Kentrup D, Tiemann K, Brand M, Hill JA, Moe OW, Kuro-o M, Kusek JW, Keane MG, Wolf M
J. Clin. Invest., 2011-10-10;121(11):4393-408.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Primary gene-engineered neural stem/progenitor cells demonstrate tumor-selective migration and antitumor effects in glioma.
Authors: Mercapide J, Rappa G, Anzanello F
Int. J. Cancer, 2010-03-01;126(5):1206-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.
Authors: Strissel KJ, DeFuria J, Shaul ME, Bennett G, Greenberg AS, Obin MS
Obesity (Silver Spring), 2010-01-28;18(10):1918-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Lymphangiogenesis and angiogenesis: concurrence and/or dependence? Studies in inbred mouse strains.
Authors: Nakao S, Maruyama K, Zandi S, Melhorn MI, Taher M, Noda K, Nusayr E, Doetschman T, Hafezi-Moghadam A
FASEB J., 2009-10-26;24(2):504-13.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Self-regulation of Stat3 activity coordinates cell-cycle progression and neural crest specification.
EMBO J., 2009-10-22;29(1):55-67.
Species: Xenopus
Sample Types: Whole Cells
Applications: Bioassay -
Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis.
Authors: Chia SL, Sawaji Y, Burleigh A, McLean C, Inglis J, Saklatvala J, Vincent T
Arthritis Rheum., 2009-07-01;60(7):2019-27.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation.
Authors: Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF
Cancer Res., 2009-05-12;69(10):4537-44.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Effects of erythropoietin in skin wound healing are dose related.
Authors: Sorg H, Krueger C, Schulz T, Menger MD, Schmitz F, Vollmar B
FASEB J., 2009-04-27;23(9):3049-58.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice.
Authors: Nakagomi T, Taguchi A, Fujimori Y, Saino O, Nakano-Doi A, Kubo S, Gotoh A, Soma T, Yoshikawa H, Nishizaki T, Nakagomi N, Stern DM, Matsuyama T
Eur. J. Neurosci., 2009-04-17;29(0):1842-52.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth.
Authors: Funa NS, Kriz V, Zang G, Calounova G, Akerblom B, Mares J, Larsson E, Sun Y, Betsholtz C, Welsh M
Cancer Res., 2009-02-17;69(5):2141-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
Authors: Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, Ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP
J. Neurosci., 2008-12-17;28(51):13978-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Ectopic expression of angiopoietin-1 promotes neuronal differentiation in neural progenitor cells through the Akt pathway.
Authors: Bai Y, Cui M, Meng Z, Shen L, He Q, Zhang X, Chen F, Xiao J
Biochem. Biophys. Res. Commun., 2008-11-24;378(2):296-301.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor.
Authors: Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, Sudhakar A, Salo T, Kalluri R
Exp. Cell Res., 2008-08-26;314(18):3292-305.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.
Authors: Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, Suzuki H, Aizawa S, Arakaki M, Yuasa K, Oka K, Chai Y, Nonaka K, Fukumoto S
J. Biol. Chem., 2008-06-17;283(34):23139-49.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Sonic hedgehog promotes the migration and proliferation of optic nerve oligodendrocyte precursors.
Authors: Merchan P, Bribian A, Sanchez-Camacho C, Lezameta M, Bovolenta P, De Castro F
Mol. Cell. Neurosci., 2007-08-01;36(3):355-68.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis.
Authors: Schwartz B, Shoseyov O, Melnikova VO, McCarty M, Leslie M, Roiz L, Smirnoff P, Hu GF, Lev D, Bar-Eli M
Cancer Res., 2007-06-01;67(11):5258-66.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice.
Authors: Gupta S, Ramjaun AR, Haiko P, Wang Y, Warne PH, Nicke B, Nye E, Stamp G, Alitalo K, Downward J
Cell, 2007-06-01;129(5):957-68.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells.
Authors: Chang MY, Sun W, Ochiai W, Nakashima K, Kim SY, Park CH, Kang JS, Shim JW, Jo AY, Kang CS, Lee YS, Kim JS, Lee SH
Mol. Cell. Biol., 2007-04-16;27(12):4293-305.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Ex vivo generation of mature and functional human smooth muscle cells differentiated from skeletal myoblasts.
Authors: Le Ricousse-Roussanne S, Larghero J, Zini JM, Barateau V, Foubert P, Uzan G, Liu X, Lacassagne MN, Ternaux B, Robert I, Benbunan M, Vilquin JT, Vauchez K, Tobelem G, Marolleau JP
Exp. Cell Res., 2007-02-08;313(7):1337-46.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Bone morphogenetic protein-mediated modulation of lineage diversification during neural differentiation of embryonic stem cells.
Authors: Gossrau G, Thiele J, Konang R, Schmandt T, Brustle O
Stem Cells, 2007-01-11;25(4):939-49.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay
FAQs
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What receptors does FGF basic bind?
FGF receptor specificity has been reviewed in multiple citations. Please find more information at: //www.rndsystems.com/resources/articles/fibroblast-growth-factors-and-their-receptors
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