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Recombinant Mouse CXCL1/KC Protein

Catalog #: 453-KC
60 Citations 7 Reviews Datasheet

Carrier Free

Catalog # Availability Size / Price Qty
453-KC-010/CF
453-KC-050/CF

With Carrier

Catalog # Availability Size / Price Qty
453-KC-010
453-KC-050
R&D Systems Recombinant Proteins and Enzymes
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Citations (60)
FAQs
Reviews (7)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Mouse CXCL1/KC Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CXCR2. The ED50 for this effect is 3-15 ng/mL.
Source
E. coli-derived mouse CXCL1/GRO alpha/KC/CINC-1 protein
Arg20-Lys96
Accession #
P12850
N-terminal Sequence
Analysis
Arg20
Predicted Molecular Mass
8 kDa

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453-KC (with carrier)

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453-KC/CF (carrier free)

Product Datasheet

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

453-KC

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

453-KC/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CXCL1/GRO alpha/KC/CINC-1

CXCL1, also known as KC, GRO alpha, and CINC-1, is an approximately 8 kDa proinflammatory chemokine that plays a key role in neutrophil migration and activation (1). Mature mouse CXCL1 shares 64% and 92% aa sequence identity with human and rat CXCL1, respectively [oquendo 4133, ryseck 266, cochran 939]. It is produced by many cell types in inflammatory sites and during chronic inflammatory diseases (1). CXCL1 can associate into bioactive dimers and primarily signals through CXCR2/IL-8 RB but can also bind with lower affinity to CXCR2/IL-8 RA (5-7). It induces neutrophil migration, extravasation, respiratory burst, and degranulation and also induces T cells to produce proinflammatory IL-17 (6, 8, 9). CXCL1 additionally binds to Syndecan-1 on epithelial cells which acts as a sink for CXCL1 activity until Syndecan-1 cleavage by MMP-7 (10). CXCL1 is up-regulated in spinal cord astrocytes by inflammatory stimuli or tumor cell injection, and it exacerbates pain sensation by potentiating excitatory NMDA neurotransmission (11, 12). In the circulatory system, CXCL1 interacts with CXCR2 on endothelial cells to promote lymphatic tube formation and angiogenesis (13, 14). It promotes the hypertrophic differentiation of chondrocytes resulting in cartilage matrix deposition, calcification, and remodeling (15). It interacts with both CXCR1 and CXCR2 on adipose stromal cells and promotes their recruitment to prostate tumors in obese patients (16). It also binds CXCR2 on ovarian cancer cells, leading to cleavage of cell surface HB-EGF, transactivation of EGF R, and cell proliferation (17).

References
  1. Strieter, R.M. et al. (2005) Cytokine Growth Factor Rev. 16:593.
  2. Cochran, B.H. et al. (1983) Cell 33:939.
  3. Oquendo, P. et al. (1989) J. Biol. Chem. 264:4133.
  4. Ryseck, R.P. et al. (1989) Exp. Cell Res. 180:266.
  5. Sawant, K.V. et al. (2015) J. Innate Immun. 7:647.
  6. Geiser, T. et al. (1993) J. Biol. Chem. 268:15419.
  7. Ahuja, S.K. and P.M. Murphy (1996) J. Biol. Chem. 271:20545.
  8. Jin, L. et al. (2014) J. Immunol. 193:3549.
  9. De Filippo, K. et al. (2013) Blood 121:4930.
  10. Gill, S.E. et al. (2016) Am. J. Respir. Cell. Mol. Biol. PMID 26934670.
  11. Cao, D.-L. et al. (2014) Exp. Neurol. 261:328.
  12. Xu, J. et al. (2014) J. Neuroinflamm. 11:38.
  13. Xu, J. et al. (2012) Int. J. Cancer 130:787.
  14. Miyake, M. et al. (2013) Lab. Invest. 93:768.
  15. Merz, D. et al. (2003) J. Immunol. 171:4406.
  16. Zhang, T. et al. (2016) Nat. Commun. 7:11674.
  17. Bolitho, C. et al. (2010) Endocr. Relat. Cancer 17:929.
Entrez Gene IDs
2919 (Human); 14825 (Mouse); 81503 (Rat)
Alternate Names
CINC1; CINC-1; CXCL1; FSP; GRO alpha; GRO1; GROa; KC; MGSA; MGSA-a; MGSA-alpha; NAP-3; SCYB1

Citations for Recombinant Mouse CXCL1/KC Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

60 Citations: Showing 1 - 10
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  1. P-selectin-dependent leukocyte adhesion is governed by endolysosomal two-pore channel 2
    Authors: Goretzko, J;Pauels, I;Heitzig, N;Thomas, K;Kardell, M;Na beta, J;Krogsaeter, EK;Schloer, S;Spix, B;Linard Matos, AL;Leser, C;Wegner, T;Glorius, F;Bracher, F;Gerke, V;Rossaint, J;Grimm, C;Rescher, U;
    Cell reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  2. A humanized beta2 integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in�vivo
    Authors: L Wen, A Marki, Z Wang, M Orecchioni, J Makings, M Billitti, E Wang, SSA Suthahar, K Kim, WB Kiosses, Z Mikulski, K Ley
    Cell Reports, 2022-05-31;39(9):110876.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Brain motor and fear circuits regulate leukocytes during acute stress
    Authors: WC Poller, J Downey, AA Mooslechne, N Khan, L Li, CT Chan, CS McAlpine, C Xu, F Kahles, S He, H Janssen, JE Mindur, S Singh, MG Kiss, L Alonso-Her, Y Iwamoto, RH Kohler, LP Wong, K Chetal, SJ Russo, RI Sadreyev, R Weissleder, M Nahrendorf, PS Frenette, M Divangahi, FK Swirski
    Nature, 2022-05-30;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  4. Humanized beta2 Integrin-Expressing Hoxb8 Cells Serve as Model to Study Integrin Activation
    Authors: T Bromberger, S Klapproth, M Sperandio, M Moser
    Cells, 2022-05-03;11(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function
    Authors: HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore
    JCI Insight, 2022-02-22;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  6. Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound
    Authors: R Roy, J Zayas, SK Singh, K Delgado, SJ Wood, MF Mohamed, DM Frausto, YA Albalawi, TP Price, R Estupinian, EF Giurini, TM Kuzel, A Zloza, J Reiser, SH Shafikhani
    Elife, 2022-02-03;11(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Behavioural immune landscapes of inflammation
    Authors: G Crainiciuc, M Palomino-S, M Molina-Mor, J Sicilia, DG Aragones, JLY Li, R Madurga, JM Adrover, A Aroca-Crev, S Martin-Sal, AS Del Valle, SD Castillo, HCE Welch, O Soehnlein, M Graupera, F Sánchez-Ca, A Zarbock, TE Smithgall, M Di Pilato, TR Mempel, PL Tharaux, SF González, A Ayuso-Saci, LG Ng, GF Calvo, I González-D, F Díaz-de-Ma, A Hidalgo
    Nature, 2022-01-05;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  8. TNF-alpha-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling
    Authors: P Agarwal, H Li, K Choi, K Hueneman, J He, RS Welner, DT Starczynow, R Bhatia
    Cell Reports, 2021-07-13;36(2):109386.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. NLRP6 modulates neutrophil homeostasis in bacterial pneumonia-derived sepsis
    Authors: S Cai, S Paudel, L Jin, L Ghimire, CM Taylor, N Wakamatsu, D Bhattarai, S Jeyaseelan
    Mucosal Immunol, 2020-11-23;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  10. Influenza virus infection augments susceptibility to respiratory Yersinia pestis exposure and impacts the efficacy of antiplague antibiotic treatments
    Authors: Y Vagima, D Gur, N Erez, H Achdout, M Aftalion, Y Levy, A Zauberman, A Tidhar, H Gutman, S Lazar, T Israely, N Paran, S Melamed, T Brosh-Niss, T Chitlaru, I Sagi, E Mamroud
    Sci Rep, 2020-11-05;10(1):19116.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  11. Epithelial membrane protein 2 governs transepithelial migration of neutrophils into the airspace
    Authors: WC Lin, KM Gowdy, JH Madenspach, RL Zemans, K Yamamoto, MR Lyons-Cohe, H Nakano, K Janardhan, CJ Williams, DN Cook, JP Mizgerd, MB Fessler
    J. Clin. Invest., 2020-01-02;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  12. Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity
    Authors: S Sharif, N Ueda, Y Nakatani, LM Wise, S Clifton, Z Lateef, AA Mercer, SB Fleming
    Front Microbiol, 2019-06-25;10(0):1421.
    Species: Mouse
    Sample Types:
    Applications: Bioassay
  13. Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2
    Authors: FH Brennan, T Jogia, ER Gillespie, LV Blomster, XX Li, B Nowlan, GM Williams, E Jacobson, GW Osborne, FA Meunier, SM Taylor, KE Campbell, KP MacDonald, JP Levesque, TM Woodruff, MJ Ruitenberg
    JCI Insight, 2019-05-02;4(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice
    Authors: AC Luissint, HC Williams, W Kim, S Flemming, V Azcutia, RS Hilgarth, MNO Leary, TL Denning, A Nusrat, CA Parkos
    Mucosal Immunol, 2019-02-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Therapeutic effect of Lipoxin A4 �in malaria-induced acute lung injury
    Authors: TA Pádua, ND Torres, ALP Candéa, MFS Costa, JD Silva, JL Silva-Filh, FTM Costa, PRM Rocco, MC Souza, MG Henriques
    J. Leukoc. Biol., 2018-01-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Neutrophil stunning by metoprolol reduces infarct size
    Authors: J García-Pri, R Villena-Gu, M Gómez, E Bernardo, A Pun-García, I García-Lun, G Crainiciuc, R Fernández-, V Sreeramkum, R Bourio-Mar, JM García-Rui, AS Del Valle, D Sanz-Rosa, G Pizarro, A Fernández-, A Hidalgo, V Fuster, B Ibanez
    Nat Commun, 2017-04-18;8(0):14780.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Absence of DCIR1 reduces the mortality rate of endotoxemic hepatitis in mice
    Authors: T Ishiguro, T Fukawa, K Akaki, K Nagaoka, T Takeda, Y Iwakura, K Inaba, K Takahara
    Eur. J. Immunol, 2017-02-22;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice
    Authors: Clara Jana-Lui Busch
    Hepatology, 2017-02-03;0(0):.
    Applications: ELISA (Standard)
  19. HS1 deficiency impairs neutrophil recruitment in vivo and activation of the small GTPases Rac1 and Rap1
    Authors: J Latasiewic, A Artz, D Jing, MP Blanco, SM Currie, MV Avila, M Schnoor, D Vestweber
    J. Leukoc. Biol, 2017-01-25;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  20. iNKT Cell Emigration out of the Lung Vasculature Requires Neutrophils and Monocyte-Derived Dendritic Cells in Inflammation
    Cell Rep, 2016-09-20;16(12):3260-72.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  21. Allostimulatory Effects of Dendritic Cells with Characteristic Features of a Regulatory Phenotype
    PLoS ONE, 2016-08-15;11(8):e0159986.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Multi-Inhibitory Effects of A2A Adenosine Receptor Signaling on Neutrophil Adhesion Under Flow.
    Authors: Yago T, Tsukamoto H, Liu Z, Wang Y, Thompson L, McEver R
    J Immunol, 2015-09-09;195(8):3880-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. DAP12 expression in lung macrophages mediates ischemia/reperfusion injury by promoting neutrophil extravasation.
    Authors: Spahn J, Li W, Bribriesco A, Liu J, Shen H, Ibricevic A, Pan J, Zinselmeyer B, Brody S, Goldstein D, Krupnick A, Gelman A, Miller M, Kreisel D
    J Immunol, 2015-03-11;194(8):4039-48.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Macrophage-inducing FasL on chondrocytes forms immune privilege in cartilage tissue engineering, enhancing in vivo regeneration.
    Authors: Fujihara Y, Takato T, Hoshi K
    Stem Cells, 2014-05-01;32(5):1208-19.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis.
    Authors: Raghuwanshi S, Smith N, Rivers E, Thomas A, Sutton N, Hu Y, Mukhopadhyay S, Chen X, Leung T, Richardson R
    J Immunol, 2013-04-15;190(10):5329-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice.
    Authors: Aeffner F, Davis I
    PLoS ONE, 2012-10-02;7(10):e46660.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  27. C-C motif chemokine CCL3 and canonical neutrophil attractants promote neutrophil extravasation through common and distinct mechanisms.
    Authors: Reichel CA, Puhr-Westerheide D, Zuchtriegel G, Uhl B, Berberich N, Zahler S, Wymann MP, Luckow B, Krombach F
    Blood, 2012-06-06;120(4):880-90.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  28. Diesel exhaust particulates exacerbate asthma-like inflammation by increasing CXC chemokines.
    Authors: Kim J, Natarajan S, Vaickus LJ, Bouchard JC, Beal D, Cruikshank WW, Remick DG
    Am. J. Pathol., 2011-10-01;179(6):2730-9.
    Applications: ELISA (Standard)
  29. The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
    Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
    J. Immunol., 2011-03-25;186(9):5425-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  30. CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.
    Authors: Jang JE, Hod EA, Spitalnik SL
    J. Clin. Invest., 2011-03-07;121(4):1397-401.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  31. Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.
    Authors: Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM
    J. Leukoc. Biol., 2010-11-02;89(2):269-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. von Willebrand factor promotes leukocyte extravasation.
    Authors: Petri B, Broermann A, Li H, Khandoga AG, Zarbock A, Krombach F, Goerge T, Schneider SW, Jones C, Nieswandt B, Wild MK, Vestweber D
    Blood, 2010-08-17;116(22):4712-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  33. A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils.
    Authors: Massena S, Christoffersson G, Hjertstrom E, Zcharia E, Vlodavsky I, Ausmees N, Rolny C, Li JP, Phillipson M
    Blood, 2010-06-08;116(11):1924-31.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. CCR2 plays a critical role in dendritic cell maturation: possible role of CCL2 and NF-kappa B.
    Authors: Jimenez F, Quinones MP, Martinez HG, Estrada CA, Clark K, Garavito E, Ibarra J, Melby PC, Ahuja SS
    J. Immunol., 2010-04-19;184(10):5571-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Regulation of leukocyte recruitment by the long pentraxin PTX3.
    Authors: Deban L, Russo RC, Sironi M, Moalli F, Scanziani M, Zambelli V, Cuccovillo I, Bastone A, Gobbi M, Valentino S, Doni A, Garlanda C, Danese S, Salvatori G, Sassano M, Evangelista V, Rossi B, Zenaro E, Constantin G, Laudanna C, Bottazzi B, Mantovani A
    Nat. Immunol., 2010-03-07;11(4):328-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  36. Respiratory syncytial virus induces airway insensitivity to beta-agonists in BALB/c mice.
    Authors: Traylor ZP, Yu EN, Davis IC
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-12-04;298(3):L437-45.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  37. Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease.
    Authors: Schneider DJ, Lindsay JC, Zhou Y, Molina JG, Blackburn MR
    FASEB J., 2009-08-31;24(1):70-80.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  38. Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness.
    Authors: Wilson RH, Whitehead GS, Nakano H, Free ME, Kolls JK, Cook DN
    Am. J. Respir. Crit. Care Med., 2009-08-06;180(8):720-30.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  39. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
    Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
    Proc. Natl. Acad. Sci. U.S.A., 2009-03-16;106(14):5954-9.
    Applications: ELISA (Standard)
  40. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
    Microbes Infect., 2009-03-13;11(4):524-30.
    Applications: ELISA (Standard)
  41. Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases.
    Authors: Koenen RR, Pruessmeyer J, Soehnlein O, Fraemohs L, Zernecke A, Schwarz N, Reiss K, Sarabi A, Lindbom L, Hackeng TM, Weber C, Ludwig A
    Blood, 2009-03-03;113(19):4799-809.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  42. The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection.
    Authors: Chen SM, Cheng DS, Williams BJ, Sherrill TP, Han W, Chont M, Saint-Jean L, Christman JW, Sadikot RT, Yull FE, Blackwell TS
    Clin. Exp. Immunol., 2008-07-18;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  43. Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo.
    Authors: Kerfoot SM, Andonegui G, Bonder CS, Liu L
    Am. J. Physiol. Heart Circ. Physiol., 2008-04-18;294(6):H2524-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  44. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
    Immunology, 2008-04-03;125(2):272-9.
    Applications: ELISA (Standard)
  45. Effects of liver X receptor agonist treatment on pulmonary inflammation and host defense.
    Authors: Smoak K, Madenspacher J, Jeyaseelan S, Williams B, Dixon D, Poch KR, Nick JA, Worthen GS, Fessler MB
    J. Immunol., 2008-03-01;180(5):3305-12.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  46. Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.
    Authors: Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T
    Eur. J. Immunol., 2007-10-01;37(10):2753-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo.
    Authors: Liu L, Puri KD, Penninger JM, Kubes P
    Blood, 2007-05-08;110(4):1191-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  48. High pressure promotes monocyte adhesion to the vascular wall.
    Authors: Riou S, Mees B, Esposito B, Merval R, Vilar J, Stengel D, Ninio E, van Haperen R, de Crom R, Tedgui A, Lehoux S
    Circ. Res., 2007-03-29;100(8):1226-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Normal neutrophil functions in sphingosine kinase type 1 and 2 knockout mice.
    Authors: Zemann B, Urtz N, Reuschel R, Mechtcheriakova D, Bornancin F, Badegruber R, Baumruker T, Billich A
    Immunol. Lett., 2007-01-30;109(1):56-63.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  50. Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8.
    Authors: Fan X, Patera AC, Pong-Kennedy A, Deno G, Gonsiorek W, Manfra DJ, Vassileva G, Zeng M, Jackson C, Sullivan L, Sharif-Rodriguez W, Opdenakker G, Van Damme J, Hedrick JA, Lundell D, Lira SA, Hipkin RW
    J. Biol. Chem., 2006-12-29;282(16):11658-66.
    Species: Mouse
    Sample Types: Complex Sample Type
    Applications: Binding Assay
  51. Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
    Authors: Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
    J. Immunol., 2006-12-15;177(12):8650-7.
    Applications: ELISA (Standard)
  52. Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice.
    Authors: Penido C, Conte FP, Chagas MS, Rodrigues CA, Pereira JF, Henriques MG
    Inflamm. Res., 2006-11-01;55(11):457-64.
    Applications: ELISA (Standard)
  53. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors.
    Authors: Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjostedt A, Edebro H, Forsman M, Bystrom M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK
    Infect. Immun., 2006-09-18;74(12):6730-8.
    Applications: ELISA (Standard)
  54. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
    Authors: Osuchowski MF, Welch K, Siddiqui J, Remick DG
    J. Immunol., 2006-08-01;177(3):1967-74.
    Applications: ELISA (Standard)
  55. Neutrophil recruitment in immunized mice depends on MIP-2 inducing the sequential release of MIP-1alpha, TNF-alpha and LTB(4).
    Authors: Ramos CD, Fernandes KS, Canetti C, Teixeira MM, Silva JS, Cunha FQ
    Eur. J. Immunol., 2006-08-01;36(8):2025-34.
    Applications: ELISA (Standard)
  56. Adenoviral-mediated overexpression of SOCS3 enhances IgG immune complex-induced acute lung injury.
    Authors: Gao H, Hoesel LM, Guo RF, Rancilio NJ, Sarma JV, Ward PA
    J. Immunol., 2006-07-01;177(1):612-20.
    Applications: ELISA (Standard)
  57. High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
    Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
    Cancer Res., 2006-04-15;66(8):4198-207.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
    Authors: Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W
    Eur. J. Immunol., 2005-09-01;35(9):2573-82.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  59. Sequential ELISA to profile multiple cytokines from small volumes.
    Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
    J. Immunol. Methods, 2005-07-01;302(1):172-81.
    Applications: ELISA (Standard)
  60. Leukocyte migration is regulated by L-selectin endoproteolytic release.
    Authors: Venturi GM, Tu L, Kadono T, Khan AI, Fujimoto Y, Oshel P, Bock CB, Miller AS, Albrecht RM, Kubes P, Steeber DA, Tedder TF
    Immunity, 2003-11-01;19(5):713-24.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo

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