Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Summary
Product Specifications
Lys22-Lys89
Analysis
Product Datasheets
350-NS (with carrier)
350-NS/CF (carrier free)
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
350-NS
Formulation | Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
350-NS/CF
Formulation | Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Scientific Data
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha (Catalog # 350-NS) chemoattracts the BaF3 mouse pro-B cells transfected with human CXCR4. The ED50 for this effect is 0.15-0.6 ng/mL.
1 μg/lane of Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.
Background: CXCL12/SDF-1 alpha
SDF-1 alpha and SDF-1 beta are the first cytokines initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a human stromal cell line as cytokines that supported the proliferation of a stromal cell-dependent pre-B-cell line.
SDF-1 alpha and SDF-1 beta cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. SDF-1 alpha and SDF-1 beta are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1 beta and absent from SDF-1 alpha. The amino acid sequence of SDF-1/PBSF identified the protein to be a member of the chemokine alpha subfamily that lacks the ELR domain. Unlike other known chemokine alpha and beta subfamily members that cluster on chromosomes 4 and 17, respectively, SDF-1/PBSF was mapped to chromosome 10q11.1. SDF-1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF-1/PBSF has been found to be a chemoattractant for T-lymphocytes and monocytes, but not neutrophils. SDF-1/PBSF was shown to be a ligand for CXCR4 (fusin/LESTR) receptor that functions as a co-receptor for lymphocyte-tropic HIV-1 strains. SDF-1/PBSF has been found to be a powerful inhibitor of infection by lymphocyte-tropic HIV-1 strains.
- Tashiro, K. et al. (1993) Science 261:600.
- Bleul, C. et al. (1996) Nature 382:829.
- Oberlin, E. et al. (1996) Nature 382:833.
Citations for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Structural insights into CXCR4 modulation and oligomerization
Authors: Saotome, K;McGoldrick, LL;Ho, JH;Ramlall, TF;Shah, S;Moore, MJ;Kim, JH;Leidich, R;Olson, WC;Franklin, MC;
Nature structural & molecular biology
Species: Human
Sample Types: Whole Cells, Protein
Applications: Bioassay -
CXCL12-loaded-hydrogel (CLG): A new device for metastatic circulating tumor cells (CTCs) capturing and characterization
Authors: Portella, L;Bertolini, G;Guardascione, G;Di Febbraro, DG;Ieranò, C;D'Alterio, C;Rea, G;Napolitano, M;Santagata, S;Trotta, AM;Camerlingo, R;Scarpa, E;Cecere, SC;Ottaiano, A;Palumbo, G;Morabito, A;Somma, T;De Rosa, G;Mayol, L;Pacelli, R;Pignata, S;Scala, S;
Heliyon
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of a CXCR4 antagonist TIQ-15 with dual tropic HIV entry inhibition properties
Authors: Zhou, Z;Guo, J;Hetrick, B;Tiwari, S;Haikerwal, A;Han, Y;Bond, VC;Huang, MB;Mankowski, MK;Snyder, BA;Hogan, PA;Sharma, SK;Liotta, DC;Reid, TE;Wilson, LJ;Wu, Y;
PLoS pathogens
Species: Hamster, Human
Sample Types: Whole Cells
Applications: Bioassay -
TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial Phenotype
Authors: Hayderi, A;Zegeye, MM;Meydan, S;Sirsjö, A;Kumawat, AK;Ljungberg, LU;
International journal of molecular sciences
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis
Authors: Park, H;Song, J;Jeong, HW;Grönloh, MLB;Koh, BI;Bovay, E;Kim, KP;Klotz, L;Thistlethwaite, PA;van Buul, JD;Sorokin, L;Adams, RH;
Nature communications
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries
Authors: Abello, J;Yin, Y;Zhao, Y;Maurer, J;Lee, J;Bodell, C;Clevenger, AJ;Burton, Z;Goeckel, ME;Lin, M;Grainger, S;Halabi, CM;Raghavan, SA;Sah, R;Stratman, AN;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Regulation of angiogenesis by endocytic trafficking mediated by cytoplasmic dynein 1 light intermediate chain 1
Authors: Johnson, D;Colijn, S;Richee, J;Yano, J;Burns, M;Davis, AE;Pham, VN;Saric, A;Jain, A;Yin, Y;Castranova, D;Melani, M;Fujita, M;Grainger, S;Bonifacino, JS;Weinstein, BM;Stratman, AN;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
SH2 domain protein E and ABL signaling regulate blood vessel size
Authors: Schumacher, JA;Wright, ZA;Rufin Florat, D;Anand, SK;Dasyani, M;Batta, SPR;Laverde, V;Ferrari, K;Klimkaite, L;Bredemeier, NO;Gurung, S;Koller, GM;Aguera, KN;Chadwick, GP;Johnson, RD;Davis, GE;Sumanas, S;
PLoS genetics
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cytotoxic chemotherapy potentiates the immune response and efficacy of combination CXCR4/PD-1 inhibition in models of pancreatic ductal adenocarcinoma
Authors: Raufi, AG;Pellicciotta, I;Palermo, CF;Sastra, SA;Chen, A;Alouani, E;Maurer, HC;May, M;Iuga, A;Rabadan, R;Olive, KP;Manji, GA;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
HER3 functions as an effective therapeutic target in triple negative breast cancer to potentiate the antitumor activity of gefitinib and paclitaxel
Authors: Lyu, H;Shen, F;Ruan, S;Tan, C;Zhou, J;Thor, AD;Liu, B;
Cancer cell international
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
StemRegenin-1 Attenuates Endothelial Progenitor Cell Senescence by Regulating the AhR Pathway-Mediated CYP1A1 and ROS Generation
Authors: Lim, HJ;Jang, WB;Rethineswaran, VK;Choi, J;Lee, EJ;Park, S;Jeong, Y;Ha, JS;Yun, J;Choi, YJ;Hong, YJ;Kwon, SM;
Cells
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
Authors: Toffali, L;D'Ulivo, B;Giagulli, C;Montresor, A;Zenaro, E;Delledonne, M;Rossato, M;Iadarola, B;Sbarbati, A;Bernardi, P;Angelini, G;Rossi, B;Lopez, N;Linke, WA;Unger, A;Di Silvestre, D;Benazzi, L;De Palma, A;Motta, S;Constantin, G;Mauri, P;Laudanna, C;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy
Authors: Shariatzadeh, M;Nagtzaam, NMA;van Vark-van der Zee, L;van Holten-Neelen, C;Verhoeven, AJM;Dehairs, J;Swinnen, JV;Leijten, F;Ten Berge, JC;Ciriano, JPM;Wong, KT;Mulder, M;Leenen, PJM;Dik, WA;
Investigative ophthalmology & visual science
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Stem cell-nanomedicine system as a theranostic bio-gadolinium agent for targeted neutron capture cancer therapy
Authors: YH Lai, CY Su, HW Cheng, CY Chu, LB Jeng, CS Chiang, WC Shyu, SY Chen
Nature Communications, 2023-01-18;14(1):285.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer
Authors: M Tobiume, A Mitsuhashi, A Saijo, H Ogino, T Afroj, H Ogawa, H Goto, S Sato, A Abe, K Haji, R Ozaki, H Takizawa, Y Nishioka
Oncology Letters, 2022-09-30;24(5):417.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
SDF?1alpha/CXCR4 signaling promotes capillary tube formation of human retinal vascular endothelial cells by activating ERK1/2 and PI3K pathways in�vitro
Authors: X Yuan, H Wu, X Li, L Chen, Y Xiao, Z Chen, G Liu, P Lu
Molecular Medicine Reports, 2022-08-10;26(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
DOCK2 is involved in the host genetics and biology of severe COVID-19
Authors: H Namkoong, R Edahiro, T Takano, H Nishihara, Y Shirai, K Sonehara, H Tanaka, S Azekawa, Y Mikami, H Lee, T Hasegawa, K Okudela, D Okuzaki, D Motooka, M Kanai, T Naito, K Yamamoto, QS Wang, R Saiki, R Ishihara, Y Matsubara, J Hamamoto, H Hayashi, Y Yoshimura, N Tachikawa, E Yanagita, T Hyugaji, E Shimizu, K Katayama, Y Kato, T Morita, K Takahashi, N Harada, T Naito, M Hiki, Y Matsushita, H Takagi, R Aoki, A Nakamura, S Harada, H Sasano, H Kabata, K Masaki, H Kamata, S Ikemura, S Chubachi, S Okamori, H Terai, A Morita, T Asakura, J Sasaki, H Morisaki, Y Uwamino, K Nanki, S Uchida, S Uno, T Nishimura, T Ishiguro, T Isono, S Shibata, Y Matsui, C Hosoda, K Takano, T Nishida, Y Kobayashi, Y Takaku, N Takayanagi, S Ueda, A Tada, M Miyawaki, M Yamamoto, E Yoshida, R Hayashi, T Nagasaka, S Arai, Y Kaneko, K Sasaki, E Tagaya, M Kawana, K Arimura, K Takahashi, T Anzai, S Ito, A Endo, Y Uchimura, Y Miyazaki, T Honda, T Tateishi, S Tohda, N Ichimura, K Sonobe, CT Sassa, J Nakajima, Y Nakano, Y Nakajima, R Anan, R Arai, Y Kurihara, Y Harada, K Nishio, T Ueda, M Azuma, R Saito, T Sado, Y Miyazaki, R Sato, Y Haruta, T Nagasaki, Y Yasui, Y Hasegawa, Y Mutoh, T Kimura, T Sato, R Takei, S Hagimoto, Y Noguchi, Y Yamano, H Sasano, S Ota, Y Nakamori, K Yoshiya, F Saito, T Yoshihara, D Wada, H Iwamura, S Kanayama, S Maruyama, T Yoshiyama, K Ohta, H Kokuto, H Ogata, Y Tanaka, K Arakawa, M Shimoda, T Osawa, H Tateno, I Hase, S Yoshida, S Suzuki, M Kawada, H Horinouchi, F Saito, K Mitamura, M Hagihara, J Ochi, T Uchida, R Baba, D Arai, T Ogura, H Takahashi, S Hagiwara, G Nagao, S Konishi, I Nakachi, K Murakami, M Yamada, H Sugiura, H Sano, S Matsumoto, N Kimura, Y Ono, H Baba, Y Suzuki, S Nakayama, K Masuzawa, S Namba, K Suzuki, Y Naito, YC Liu, A Takuwa, F Sugihara, JB Wing, S Sakakibara, N Hizawa, T Shiroyama, S Miyawaki, Y Kawamura, A Nakayama, H Matsuo, Y Maeda, T Nii, Y Noda, T Niitsu, Y Adachi, T Enomoto, S Amiya, R Hara, Y Yamaguchi, T Murakami, T Kuge, K Matsumoto, Y Yamamoto, M Yamamoto, M Yoneda, T Kishikawa, S Yamada, S Kawabata, N Kijima, M Takagaki, N Sasa, Y Ueno, M Suzuki, N Takemoto, H Eguchi, T Fukusumi, T Imai, M Fukushima, H Kishima, H Inohara, K Tomono, K Kato, M Takahashi, F Matsuda, H Hirata, Y Takeda, H Koh, T Manabe, Y Funatsu, F Ito, T Fukui, K Shinozuka, S Kohashi, M Miyazaki, T Shoko, M Kojima, T Adachi, M Ishikawa, K Takahashi, T Inoue, T Hirano, K Kobayashi, H Takaoka, K Watanabe, N Miyazawa, Y Kimura, R Sado, H Sugimoto, A Kamiya, N Kuwahara, A Fujiwara, T Matsunaga, Y Sato, T Okada, Y Hirai, H Kawashima, A Narita, K Niwa, Y Sekikawa, K Nishi, M Nishitsuji, M Tani, J Suzuki, H Nakatsumi, T Ogura, H Kitamura, E Hagiwara, K Murohashi, H Okabayashi, T Mochimaru, S Nukaga, R Satomi, Y Oyamada, N Mori, T Baba, Y Fukui, M Odate, S Mashimo, Y Makino, K Yagi, M Hashiguchi, J Kagyo, T Shiomi, S Fuke, H Saito, T Tsuchida, S Fujitani, M Takita, D Morikawa, T Yoshida, T Izumo, M Inomata, N Kuse, N Awano, M Tone, A Ito, Y Nakamura, K Hoshino, J Maruyama, H Ishikura, T Takata, T Odani, M Amishima, T Hattori, Y Shichinohe, T Kagaya, T Kita, K Ohta, S Sakagami, K Koshida, K Hayashi, T Shimizu, Y Kozu, H Hiranuma, Y Gon, N Izumi, K Nagata, K Ueda, R Taki, S Hanada, K Kawamura, K Ichikado, K Nishiyama, H Muranaka, K Nakamura, N Hashimoto, K Wakahara, K Sakamoto, N Omote, A Ando, N Kodama, Y Kaneyama, S Maeda, T Kuraki, T Matsumoto, K Yokote, TA Nakada, R Abe, T Oshima, T Shimada, M Harada, T Takahashi, H Ono, T Sakurai, T Shibusawa, Y Kimizuka, A Kawana, T Sano, C Watanabe, R Suematsu, H Sageshima, A Yoshifuji, K Ito, S Takahashi, K Ishioka, M Nakamura, M Masuda, A Wakabayash, H Watanabe, S Ueda, M Nishikawa, Y Chihara, M Takeuchi, K Onoi, J Shinozuka, A Sueyoshi, Y Nagasaki, M Okamoto, S Ishihara, M Shimo, Y Tokunaga, Y Kusaka, T Ohba, S Isogai, A Ogawa, T Inoue, S Fukuyama, Y Eriguchi, A Yonekawa, K Kan-O, K Matsumoto, K Kanaoka, S Ihara, K Komuta, Y Inoue, S Chiba, K Yamagata, Y Hiramatsu, H Kai, K Asano, T Oguma, Y Ito, S Hashimoto, M Yamasaki, Y Kasamatsu, Y Komase, N Hida, T Tsuburai, B Oyama, M Takada, H Kanda, Y Kitagawa, T Fukuta, T Miyake, S Yoshida, S Ogura, S Abe, Y Kono, Y Togashi, H Takoi, R Kikuchi, S Ogawa, T Ogata, S Ishihara, A Kanehiro, S Ozaki, Y Fuchimoto, S Wada, N Fujimoto, K Nishiyama, M Terashima, S Beppu, K Yoshida, O Narumoto, H Nagai, N Ooshima, M Motegi, A Umeda, K Miyagawa, H Shimada, M Endo, Y Ohira, M Watanabe, S Inoue, A Igarashi, M Sato, H Sagara, A Tanaka, S Ohta, T Kimura, Y Shibata, Y Tanino, T Nikaido, H Minemura, Y Sato, Y Yamada, T Hashino, M Shinoki, H Iwagoe, H Takahashi, K Fujii, H Kishi, M Kanai, T Imamura, T Yamashita, M Yatomi, T Maeno, S Hayashi, M Takahashi, M Kuramochi, I Kamimaki, Y Tominaga, T Ishii, M Utsugi, A Ono, T Tanaka, T Kashiwada, K Fujita, Y Saito, M Seike, H Watanabe, H Matsuse, N Kodaka, C Nakano, T Oshio, T Hirouchi, S Makino, M Egi, Biobank Ja, Y Omae, Y Nannya, T Ueno, K Katayama, M Ai, Y Fukui, A Kumanogoh, T Sato, N Hasegawa, K Tokunaga, M Ishii, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Y Okada
Nature, 2022-08-08;609(7928):754-760.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Inflammation down regulates stromal cell-derived factor 1alpha in the early phase of pulpitis
Authors: S Leng, L Liu, W Xu, F Yang, J Du, L Ye, D Huang, L Zhang
Cytokine, 2022-08-02;158(0):155983.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration
Authors: M Mastrogiov, P Vargas, T Rose, C Cuche, E Esposito, M Juzans, H Laude, A Schneider, M Bernard, S Goyard, C Renaudat, MN Ungeheuer, J Delon, A Alcover, V Di Bartolo
Science Advances, 2022-04-13;8(15):eabl5942.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia
Authors: TA Burley, A Hesketh, G Bucca, E Kennedy, EE Ladikou, BP Towler, S Mitchell, CP Smith, C Fegan, R Johnston, A Pepper, C Pepper
Cancers, 2022-03-22;14(7):.
Species: Human
Sample Types: Whole Cell
Applications: Bioassay -
Discovery of Small Molecule Activators of Chemokine Receptor CXCR4 That Improve Diabetic Wound Healing
Authors: J Xu, J Hu, S Idlett-Ali, L Zhang, K Caples, S Peddibhotl, M Reeves, C Zgheib, S Malany, KW Liechty
International Journal of Molecular Sciences, 2022-02-16;23(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Galphai signaling
Authors: ML Capitano, Y Sammour, J Ropa, M Legendre, N Mor-Vaknin, DM Markovitz
Journal of leukocyte biology, 2022-02-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis
Authors: C Fielding, A García-Gar, C Korn, S Gadomski, Z Fang, JL Reguera, JA Pérez-Simó, B Göttgens, S Méndez-Fer
Nature Communications, 2022-01-27;13(1):543.
Species: Mouse
Sample Types: Bone Marrow Lavage Fluid
Applications: ELISA Control -
Role of CCR3 in respiratory syncytial virus infection of airway epithelial cells.
Authors: Wellemans V, Benhassou H, Fuselier E, Bellesort F, Dury S, Lebargy F, Dormoy V, Fichel C, Naour R, Gounni A, Lamkhioued B
iScience, 2021-11-14;24(12):103433.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy
Authors: T Radaszkiew, M Nosková, K Gömöryová, O Vondálová, KA Radaszkiew, M Picková, R Víchová, T Gybe?, K Kaiser, L Demková, L Ku?erová, T Bárta, D Pot?šil, Z Zdráhal, K Sou?ek, V Bryja
Elife, 2021-10-27;10(0):.
Species: Human
Sample Types: Transduced Whole Cells
Applications: Bioassay -
Dual role for CXCL12 signaling in semilunar valve development
Authors: LA Ridge, D Kewbank, D Schütz, R Stumm, PJ Scambler, S Ivins
Cell Reports, 2021-08-24;36(8):109610.
Species: Mouse
Sample Types: Organoid
Applications: Bioassay -
VLA-4 Induces Chemoresistance of T Cell Acute Lymphoblastic Leukemia Cells via PYK2-Mediated Drug Efflux
Authors: S Berrazouan, A Doucet, M Boisvert, F Barabé, F Aoudjit
Cancers, 2021-07-14;13(14):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression
Authors: Y Fu, Z Zhang, Z Yang, Y Jiang, X Han, J Xu, Z Chu, H Ding, S He, H Shang
Cell Reports, 2021-07-13;36(2):109344.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
miR-126-3p is essential for CXCL12-induced angiogenesis
Authors: K Bassand, L Metzinger, M Naïm, N Mouhoubi, O Haddad, V Assoun, N Zaïdi, O Sainte-Cat, A Butt, E Guyot, O Oudar, C Laguillier, A Sutton, N Charnaux, V Metzinger-, H Hlawaty
Journal of Cellular and Molecular Medicine, 2021-06-12;0(0):.
Species: Rat
Sample Types: Whole Tissue
Applications: Bioassay -
Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin &beta1-ILK-&beta-catenin-JUN axis
Authors: A Yuzuriha, S Nakamura, N Sugimoto, S Kihara, M Nakagawa, T Yamamoto, K Sekiguchi, K Eto
Stem Cell Research, 2021-03-16;53(0):102287.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCR4 uses STAT3-mediated slug expression to maintain radioresistance of non-small cell lung cancer cells: emerges as a potential prognostic biomarker for lung cancer
Authors: JY Kim, HJ Kim, CW Jung, TS Lee, EH Kim, MJ Park
Cell Death & Disease, 2021-01-07;12(1):48.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCL12-mediated HOXB5 overexpression facilitates Colorectal Cancer metastasis through transactivating CXCR4 and ITGB3
Authors: W Feng, W Huang, J Chen, C Qiao, D Liu, X Ji, M Xie, T Zhang, Y Wang, M Sun, D Tian, D Fan, Y Nie, K Wu, L Xia
Theranostics, 2021-01-01;11(6):2612-2633.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response
Authors: D Biasci, M Smoragiewi, CM Connell, Z Wang, Y Gao, JED Thaventhir, B Basu, L Magiera, TI Johnson, L Bax, A Gopinathan, C Isherwood, FA Gallagher, M Pawula, I Hudecova, D Gale, N Rosenfeld, P Barmpounak, EC Popa, R Brais, E Godfrey, F Mir, FM Richards, DT Fearon, T Janowitz, DI Jodrell
Proc Natl Acad Sci U S A, 2020-10-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
Authors: A Fumagalli, J Heuninck, A Pizzoccaro, E Moutin, J Koenen, M Séveno, T Durroux, MP Junier, G Schlecht-L, F Bachelerie, D Schütz, R Stumm, MJ Smit, NC Guérineau, S Chaumont-D, P Marin
Nat Commun, 2020-09-25;11(1):4855.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles
Authors: PR Norden, Z Sun, GE Davis
PLoS ONE, 2020-06-22;15(6):e0235116.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Development of a Sustained Release Nano-In-Gel Delivery System for the Chemotactic and Angiogenic Growth Factor Stromal-Derived Factor 1alpha
Authors: J O'Dwyer, M Cullen, S Fattah, R Murphy, S Stefanovic, L Kovarova, M Pravda, V Velebny, A Heise, GP Duffy, SA Cryan
Pharmaceutics, 2020-06-04;12(6):.
Species: Human
Sample Types: Protein
Applications: Bioassay -
Brief ex vivo Fas-ligand incubation attenuates GvHD without compromising stem cell graft performance
Authors: H Levy-Baraz, L Shachnai-P, G Rodionov, A Saar, M Rosenzwaig, L Gez, A Rodin, N Marelly, M Abraham, I Mishalian, H Wildbaum, T Katz, Y Baar, S Yarkoni, R Bakimer-Kl, A Peled, T Zuckerman, J Stein
Bone Marrow Transplant., 2020-05-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway
Authors: J Lim, J Heo, H Ju, JW Shin, Y Kim, S Lee, HY Yu, CM Ryu, H Yun, S Song, KS Hong, HM Chung, HR Kim, JS Roe, K Choi, IG Kim, EM Jeong, DM Shin
Sci Adv, 2020-04-15;6(16):eaba1334.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina
Authors: H Cho, BL Macklin, YY Lin, L Zhou, MJ Lai, G Lee, S Gerecht, EJ Duh
JCI Insight, 2020-03-26;5(6):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8+ T Cells in Head and Neck Cancer
Authors: AA Chimote, VS Gawali, HS Newton, TM Wise-Drape, L Conforti
Front Pharmacol, 2020-02-28;11(0):143.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Role and therapeutic effects of skeletal muscle-derived non-myogenic cells in a rat myocardial infarction model
Authors: H Iseoka, S Miyagawa, A Saito, A Harada, Y Sawa
Stem Cell Res Ther, 2020-02-18;11(1):69.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
LRCH1 suppresses migration of CD4+ T cells and refers to disease activity in ulcerative colitis
Authors: Y Wang, H Zhang, H He, K Ai, W Yu, X Xiao, Y Qin, L Zhang, H Xiong, G Zhou
Int J Med Sci, 2020-02-17;17(5):599-608.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mitochondrial mass governs the extent of human T cell senescence
Authors: LA Callender, EC Carroll, EA Bober, AN Akbar, E Solito, SM Henson
Aging Cell, 2019-12-02;0(0):e13067.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Distinguishing human peripheral blood CD16+ myeloid cells based on phenotypic characteristics
Authors: PD Fromm, PA Silveira, JL Hsu, MS Papadimitr, TH Lo, X Ju, F Kupresanin, A Romano, WH Hsu, CE Bryant, B Kong, E Abadir, A Mekkawy, H M McGuire, BFS Groth, I Cunningham, E Newman, J Gibson, PM Hogarth, DNJ Hart, GJ Clark
J. Leukoc. Biol., 2019-11-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3)
Authors: F Caccuri, A Bugatti, S Corbellini, S Roversi, A Zani, P Mazzuca, S Marsico, A Caruso, C Giagulli
Int J Mol Sci, 2019-10-24;20(21):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths
Authors: NM Belle, Y Ji, K Herbine, Y Wei, J Park, K Zullo, LY Hung, S Srivatsa, T Young, T Oniskey, C Pastore, W Nieves, M Somsouk, DR Herbert
Nat Commun, 2019-09-27;10(1):4408.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas
Authors: L Chen, J Ouyang, K Wienand, K Bojarczuk, Y Hao, B Chapuy, D Neuberg, P Juszczynsk, LN Lawton, SJ Rodig, S Monti, MA Shipp
Haematologica, 2019-08-30;105(5):1361-1368.
Species: Human
Sample Types:
Applications: Functional Assay -
TCF12 promotes the tumorigenesis and metastasis of hepatocellular carcinoma via upregulation of CXCR4 expression
Authors: J Yang, L Zhang, Z Jiang, C Ge, F Zhao, J Jiang, H Tian, T Chen, H Xie, Y Cui, M Yao, H Li, J Li
Theranostics, 2019-08-12;9(20):5810-5827.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells
Authors: C Ieranò, C D'Alterio, S Giarra, M Napolitano, G Rea, L Portella, A Santagata, AM Trotta, A Barbieri, V Campani, A Luciano, C Arra, AM Anniciello, G Botti, L Mayol, G De Rosa, R Pacelli, S Scala
Cell Death Dis, 2019-07-22;10(8):562.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: In Vivo, Migration -
Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment
Authors: DJ Wessels, N Pradhan, YN Park, MA Klepitsch, DF Lusche, KJ Daniels, KD Conway, ER Voss, SV Hegde, TP Conway, DR Soll
PLoS ONE, 2019-06-24;14(6):e0218854.
Species: Human
Sample Types: Recombinant Protein, Whole Cells
Applications: Bioassay, Cell Culture, Positive Control -
Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling
Authors: ML Capitano, N Mor-Vaknin, AK Saha, S Cooper, M Legendre, H Guo, R Contreras-, F Kappes, MA Sartor, CT Lee, X Huang, DM Markovitz, HE Broxmeyer
J. Clin. Invest., 2019-05-20;130(0):2555-2570.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
RhoGDI2 positively regulates the Rho GTPases activation in response to the ?2 outside-in signaling in T cells adhesion and migration on ICAM-1
Authors: W Liu, X Wang, S Wang, X Ba, T Xu, X Wang, X Zeng
J. Leukoc. Biol., 2019-05-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer
Authors: S Li, KW Fong, G Gritsina, A Zhang, JC Zhao, J Kim, A Sharp, W Yuan, C Aversa, XJ Yang, PS Nelson, FY Feng, AM Chinnaiyan, JS de Bono, C Morrissey, MB Rettig, J Yu
Cancer Res., 2019-04-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates
Authors: MJ Costa, J Kudaravall, JT Ma, WH Ho, K Delaria, C Holz, A Stauffer, AG Chunyk, Q Zong, E Blasi, B Buetow, TT Tran, K Lindquist, M Dorywalska, A Rajpal, DL Shelton, P Strop, SH Liu
Sci Rep, 2019-02-21;9(1):2443.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis
Authors: MR Blatchley, F Hall, S Wang, HC Pruitt, S Gerecht
Sci Adv, 2019;5(3):eaau7518.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo
Authors: LF Pavon, TT Sibov, AV de Souza, EF da Cruz, SMF Malheiros, FR Cabral, JG de Souza, P Boufleur, DM de Oliveir, SRC de Toledo, LC Marti, JM Malheiros, FF Paiva, A Tannús, SM de Oliveir, AM Chudzinski, MA de Paiva N, S Cavalheiro
Stem Cell Res Ther, 2018-11-09;9(1):310.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma
Authors: S Mamand, RL Allchin, MJ Ahearne, SD Wagner
Sci Rep, 2018-09-21;8(1):14216.
Species: Human
Sample Types: Whole Cells
-
Senescent fibroblasts drive ageing pigmentation: ?A potential therapeutic target for senile lentigo
Authors: JE Yoon, Y Kim, S Kwon, M Kim, YH Kim, JH Kim, TJ Park, HY Kang
Theranostics, 2018-09-09;8(17):4620-4632.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A feed-forward loop between nuclear translocation of CXCR4 and HIF-1? promotes renal cell carcinoma metastasis
Authors: Y Bao, Z Wang, B Liu, X Lu, Y Xiong, J Shi, P Li, J Chen, Z Zhang, M Chen, L Wang, Z Wu
Oncogene, 2018-09-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Simple Physical Model Unravels Influences of Chemokine on Shape Deformation and Migration of Human Hematopoietic Stem Cells
Authors: T Ohta, C Monzel, AS Becker, AD Ho, M Tanaka
Sci Rep, 2018-07-13;8(1):10630.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells
Authors: W He, T Yang, XH Gong, RZ Qin, XD Zhang, WD Liu
Oncol Lett, 2018-07-04;16(3):3976-3982.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Biomimetic post-capillary venule expansions for leukocyte adhesion studies
Authors: BL Benson, L Li, JT Myers, RD Dorand, UA Gurkan, AY Huang, RM Ransohoff
Sci Rep, 2018-06-19;8(1):9328.
-
Phosphorylation of the ?-chain in the integrin LFA-1 enables ?2-chain phosphorylation and ?-actinin binding required for cell adhesion
Authors: F Jahan, S Madhavan, T Rolova, L Viazmina, M Grönholm, CG Gahmberg
J. Biol. Chem., 2018-06-14;0(0):.
Applications: Bioassay -
Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis
Authors: Y Nam, SM Jung, YA Rim, H Jung, K Lee, N Park, J Kim, Y Jang, YB Park, SH Park, JH Ju
PLoS ONE, 2018-06-07;13(6):e0198740.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2)
Authors: KM Dvorak, KM Pettee, K Rubinic-Mi, R Su, A Nestor-Kal, KM Eisenmann
PLoS ONE, 2018-03-29;13(3):e0195278.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Transmission of integrin ?7 transmembrane domain topology enables gut lymphoid tissue development
Authors: H Sun, F Lagarrigue, AR Gingras, Z Fan, K Ley, MH Ginsberg
J. Cell Biol., 2018-03-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Engineering of thermoresponsive gels as a fake metastatic niche
Authors: S Giarra, C Ierano, M Biondi, M Napolitano, V Campani, R Pacelli, S Scala, G De Rosa, L Mayol
Carbohydr Polym, 2018-03-10;191(0):112-118.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Stromal-derived factor 1 directly promotes genes expressed within the ovulatory cascade in feline cumulus oocyte complexes
Authors: JL Rojo, M Linari, KA Young, MC Peluffo
J. Assist. Reprod. Genet., 2018-03-08;0(0):.
Species: Feline
Sample Types: Whole Cells
Applications: Bioassay -
CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation
Authors: S Patalano, J Rodríguez-, C Colaneri, J Cotellessa, D Almanza, A Zhilin-Rot, T Riley, J Macoska
Sci Rep, 2018-02-22;8(1):3499.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy
Authors: TI Moore, J Aaron, TL Chew, TA Springer
Cell Rep, 2018-02-13;22(7):1903-1912.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma
Authors: W Tang, SG Smith, W Du, A Gugilla, J Du, JP Oliveria, K Howie, BM Salter, GM Gauvreau, PM O'Byrne, R Sehmi
Clin Transl Allergy, 2018-02-13;8(0):5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria
Authors: E Vågesjö, E Öhnstedt, A Mortier, H Lofton, F Huss, P Proost, S Roos, M Phillipson
Proc. Natl. Acad. Sci. U.S.A., 2018-02-05;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells
Authors: SYN Jamaludin, I Azimi, FM Davis, AA Peters, TJ Gonda, EW Thompson, SJ Roberts-Th, GR Monteith
Oncol Lett, 2018-01-19;15(4):4289-4295.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation
Authors: JJ Gell, J Zhao, D Chen, TJ Hunt, AT Clark
Stem Cell Res, 2018-01-04;27(0):46-56.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human Naive and Memory T Cells Display Opposite Migratory Responses to Sphingosine-1 Phosphate
Authors: A Drouillard, A Neyra, AL Mathieu, A Marçais, M Wencker, J Marvel, A Belot, T Walzer
J. Immunol., 2017-12-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome
Authors: W Oliva-Oliv, I Moreno-Ind, L Coín-Aragü, S Lhamyani, J Alcaide To, S Fernández-, J Vendrell, A Camargo, R El Bekay, FJ Tinahones
PLoS ONE, 2017-11-22;12(11):e0188324.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia
Authors: H Plešingero, P Janovská, A Mishra, L Smy?ková, L Poppová, A Libra, K Plevová, P Ovesná, L Radová, M Doubek, Š Pavlová, Š Pospíšilov, V Bryja
Haematologica, 2017-11-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Protein profiling identified key chemokines that regulate the maintenance of human pluripotent stem cells
Authors: Z Jiang, Y Li, X Ji, Y Tang, H Yu, L Ding, M Yu, Q Cui, M Zhang, Y Ma, M Li
Sci Rep, 2017-11-06;7(1):14510.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Directional migration of mesenchymal stem cells under an SDF-1? gradient on a microfluidic device
Authors: S Park, H Jang, BS Kim, C Hwang, GS Jeong, Y Park
PLoS ONE, 2017-09-08;12(9):e0184595.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Regulation of CCR7-dependent cell migration through�CCR7 homodimer formation
Authors: D Kobayashi, M Endo, H Ochi, H Hojo, M Miyasaka, H Hayasaka
Sci Rep, 2017-08-17;7(1):8536.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Endothelial progenitor cell dysfunction in acute exacerbation of chronic obstructive pulmonary disease
Authors: X Liu, Y Liu, X Huang, G Lin, C Xie
Mol Med Rep, 2017-08-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells
Authors: M Zhang, L Qiu, Y Zhang, D Xu, JC Zheng, L Jiang
Sci Rep, 2017-08-15;7(1):8289.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mechanisms of CXCR7 induction in malignant melanoma development
Authors: XJ Li, P Liu, WW Tian, ZF Li, BG Liu, JF Sun
Oncol Lett, 2017-08-04;14(4):4106-4114.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Frontline Science: CXCR7 mediates CD14(+)CD16(+) monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS
Authors: M Veenstra, DW Williams, TM Calderon, K Anastos, S Morgello, JW Berman
J. Leukoc. Biol., 2017-07-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate
Authors: PJ Stewart-Hu, TP Szasz, ER Jaeger, MD Onken, JA Cooper, SC Morley
J. Leukoc. Biol., 2017-06-21;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B-cells from apoptosis, enhance their migration and induce gene expression modifications
Authors: E Crompot, M Van Damme, K Pieters, M Vermeersch, D Perez-Morg, P Mineur, M Maerevoet, N Meuleman, D Bron, L Lagneaux, B Stamatopou
Haematologica, 2017-06-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells
Authors: JH Kim, JW Shim, DY Eum, SD Kim, SH Choi, K Yang, K Heo, MT Park
Sci Rep, 2017-06-05;7(1):2798.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Affinity biosensors using recombinant native membrane proteins displayed on exosomes: application to botulinum neurotoxin B receptor
Authors: R Desplantes, C Lévêque, B Muller, M Lotierzo, G Ferracci, M Popoff, M Seagar, R Mamoun, O El Far
Sci Rep, 2017-04-21;7(1):1032.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay -
Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis
Authors: H Al Faruque, JH Kang, SR Hwang, S Sung, MM Alam, KH Sa, EJ Nam, YR Byun, YM Kang
PLoS ONE, 2017-04-18;12(4):e0176110.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A novel recombinant antibody specific to full-length stromal derived factor-1 for potential application in biomarker studies
Authors: DI Bromage, S Taferner, M Pillai, DM Yellon, SM Davidson
PLoS ONE, 2017-04-05;12(4):e0174447.
Species: Human
Sample Types: Antibody, Plasma
Applications: ELISA (Standard), Enzyme Assay -
Vascular CXCR4 expression promotes vessel sprouting and sensitivity to sorafenib treatment in hepatocellular carcinoma
Authors: J Xu, J Liang, YM Meng, J Yan, XJ Yu, CQ Liu, L Xu, SM Zhuang, L Zheng
Clin. Cancer Res, 2017-02-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Directional delivery of RSPO1 by mesenchymal stem cells ameliorates radiation-induced intestinal injury
Authors: W Chen, S Ju, T Lu, Y Xu, X Zheng, H Wang, Y Ge, S Ju
Cytokine, 2017-02-20;95(0):27-34.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PLC?1 regulates SDF-1?-induced lymphocyte adhesion and migration to sites of inflammation
Authors: M Strazza, I Azoulay-Al, M Peled, AV Smrcka, EY Skolnik, S Srivastava, A Mor
Proc. Natl. Acad. Sci. U.S.A, 2017-02-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Hepatitis B virus X protein promotes the stem-like properties of OV6(+) cancer cells in hepatocellular carcinoma
Authors: C Wang, MD Wang, P Cheng, H Huang, W Dong, WW Zhang, PP Li, C Lin, ZY Pan, MC Wu, WP Zhou
Cell Death Dis, 2017-01-19;8(1):e2560.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Designed cell consortia as fragrance-programmable analog-to-digital converters
Authors: M Müller, S Ausländer, A Spinnler, D Ausländer, J Sikorski, M Folcher, M Fussenegge
Nat. Chem. Biol, 2017-01-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells
Authors: M Moslem, R Eggenschwi, C Wichmann, R Buhmann, T Cantz, R Henschler
Stem Cells Int, 2017-01-09;2017(0):7316354.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
MicroRNA expression profiles and networks in CXCL12?stimulated human endometrial stromal cells
Mol Med Rep, 2016-12-07;15(1):249-255.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta
Authors: Amber N Stratman
Development, 2016-12-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library
Authors: Renren Bai
Eur J Med Chem, 2016-11-24;126(0):464-475.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
SDF-1?-induced dual pairs of E-selectin/ligand mediate endothelial progenitor cell homing to critical ischemia
Sci Rep, 2016-10-07;6(0):34416.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Glioma Cell Invasion is Significantly Enhanced in Composite Hydrogel Matrices Composed of Chondroitin 4- and 4,6-Sulfated Glycosaminoglycans
Authors: MT Logun, NS Bisel, EA Tanasse, W Zhao, B Gunasekera, L Mao, L Karumbaiah
J Mater Chem B Mater Biol Med, 2016-08-26;4(36):6052-6064.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Local CXCR4 Up-regulation in Injured Arterial Wall Contributes to Intimal Hyperplasia
Authors: Xudong Shi
Stem Cells, 2016-07-17;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
HEREGULIN/ErbB3 SIGNALING ENHANCES CXCR4-DRIVEN Rac1 ACTIVATION AND BREAST CANCER CELL MOTILITY VIA HIF-1?
Mol Cell Biol, 2016-07-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation
Authors: Patricia Freund
PLoS ONE, 2016-06-01;11(6):e0156693.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: Evidence for Partial Allosteric Agonism in Comparison to CXCL12
J Biol Chem, 2016-05-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pannexin1 Channels Are Required for Chemokine-Mediated Migration of CD4+ T Lymphocytes: Role in Inflammation and Experimental Autoimmune Encephalomyelitis
Authors: S Velasquez, S Malik, SE Lutz, E Scemes, EA Eugenin
J Immunol, 2016-04-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia.
Authors: Janovska P, Poppova L, Plevova K, Plesingerova H, Behal M, Kaucka M, Ovesna P, Hlozkova M, Borsky M, Stehlikova O, Brychtova Y, Doubek M, Machalova M, Baskar S, Kozubik A, Pospisilova S, Pavlova S, Bryja V
Clin Cancer Res, 2015-08-03;22(2):459-69.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
Authors: Heinzmann D, Bangert A, Muller A, von Ungern-Sternberg S, Emschermann F, Schonberger T, Chatterjee M, Mack A, Klingel K, Kandolf R, Malesevic M, Borst O, Gawaz M, Langer H, Katus H, Fischer G, May A, Kaya Z, Seizer P
PLoS ONE, 2015-04-20;10(4):e0124606.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
Authors: Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, Falls T, Jennings V, Boileau M, Bellamy D, Bastin D, de Souza C, Alkayyal A, Zhang J, Le Boeuf F, Arulanandam R, Stubbert L, Sampath P, Thorne S, Paramanthan P, Chatterjee A, Strieter R, Burdick M, Addison C, Stojdl D, Atkins H, Auer R, Diallo J, Lichty B, Bell J
Nat Med, 2015-04-20;21(5):530-6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Bortezomib inhibits expression of TGF-beta1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells.
Authors: Chang T, Poltoratsky V, Vancurova I
J Immunol, 2015-02-13;194(6):2942-53.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Oligodendroglial maturation is dependent on intracellular protein shuttling.
Authors: Gottle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, Parras C, Kremer D, Hartung H, Cate H, Kury P
J Neurosci, 2015-01-21;35(3):906-19.
Species: Human, Rat
Sample Types: Whole Cells
Applications: Bioassay -
Protein z exerts pro-angiogenic effects and upregulates CXCR4.
Authors: Butschkau, Antje, Wagner, Nana-Mar, Genz, Berit, Vollmar, Brigitte
PLoS ONE, 2014-12-04;9(12):e113554.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals.
Authors: Williams D, Anastos K, Morgello S, Berman J
J Leukoc Biol, 2014-11-24;97(2):401-12.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Carbon monoxide down-regulates alpha4beta1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.
Authors: Chigaev A, Smagley Y, Sklar L
BMC Immunol, 2014-10-31;15(0):52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I.
Authors: Watson H, Holley R, Langford-Smith K, Wilkinson F, van Kuppevelt T, Wynn R, Wraith J, Merry C, Bigger B
J Biol Chem, 2014-10-30;289(52):36194-203.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
SDF-1alpha is a novel autocrine activator of platelets operating through its receptor CXCR4.
Authors: Walsh T, Harper M, Poole A
Cell Signal, 2014-10-05;27(1):37-46.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors.
Authors: Mendes-Da-Cruz D, Brignier A, Asnafi V, Baleydier F, Messias C, Lepelletier Y, Bedjaoui N, Renand A, Smaniotto S, Canioni D, Milpied P, Balabanian K, Bousso P, Lepretre S, Bertrand Y, Dombret H, Ifrah N, Dardenne M, Macintyre E, Savino W, Hermine O
PLoS ONE, 2014-07-28;9(7):e103405.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCL12-gamma in primary tumors drives breast cancer metastasis.
Authors: Ray P, Stacer A, Fenner J, Cavnar S, Meguiar K, Brown M, Luker K, Luker G
Oncogene, 2014-06-09;34(16):2043-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration.
Authors: Boudot A, Kerdivel G, Lecomte S, Flouriot G, Desille M, Godey F, Leveque J, Tas P, Le Drean Y, Pakdel F
BMC Cancer, 2014-06-06;14(0):407.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCR7 controls competition for recruitment of beta-arrestin 2 in cells expressing both CXCR4 and CXCR7.
Authors: Coggins N, Trakimas D, Chang S, Ehrlich A, Ray P, Luker K, Linderman J, Luker G
PLoS ONE, 2014-06-04;9(6):e98328.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells.
Authors: Richter R, Jochheim-Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, Verzijl D, Smit M, Blanchet X, von Hundelshausen P, Weber C, Forssmann W, Henschler R
Stem Cells Dev, 2014-05-27;23(16):1959-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells.
Authors: Ugarte-Berzal E, Bailon E, Amigo-Jimenez I, Albar J, Garcia-Marco J, Garcia-Pardo A
J Biol Chem, 2014-04-16;289(22):15340-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma.
Authors: Krook M, Nicholls L, Scannell C, Chugh R, Thomas D, Lawlor E
Mol Cancer Res, 2014-03-20;12(6):953-64.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
SDF-1/CXCR4 signaling preserves microvascular integrity and renal function in chronic kidney disease.
Authors: Chen L, Advani S, Thai K, Kabir M, Sood M, Gibson I, Yuen D, Connelly K, Marsden P, Kelly D, Gilbert R, Advani A
PLoS ONE, 2014-03-17;9(3):e92227.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
Authors: Lessey-Morillon E, Osborne L, Monaghan-Benson E, Guilluy C, O'Brien E, Superfine R, Burridge K
J Immunol, 2014-02-28;192(7):3390-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Circulating angiogenic cell dysfunction in patients with hereditary hemorrhagic telangiectasia.
Authors: Zucco L, Zhang Q, Kuliszewski M, Kandic I, Faughnan M, Stewart D, Kutryk M
PLoS ONE, 2014-02-25;9(2):e89927.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TNF-alpha induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways.
Authors: Lo H, Lai T, Li C, Wu W
Acta Pharmacol Sin, 2014-02-03;35(3):339-50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Complex cellular composition of solitary fibrous tumor of the prostate.
Authors: Gharaee-Kermani M, Mehra R, Robinson D, Wei J, Macoska J
Am J Pathol, 2014-01-13;184(3):732-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells.
Authors: Vermi W, Micheletti A, Lonardi S, Costantini C, Calzetti F, Nascimbeni R, Bugatti M, Codazzi M, Pinter P, Schakel K, Tamassia N, Cassatella M
Nat Commun, 2014-01-01;5(0):3029.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A paracrine network regulates the cross-talk between human lung stem cells and the stroma.
Authors: Ruiz E, Oeztuerk-Winder F, Ventura J
Nat Commun, 2014-01-01;5(0):3175.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
Authors: Smith A, Bowers S, Stratman A, Davis G
PLoS ONE, 2013-12-31;8(12):e85147.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization.
Authors: Hoellenriegel J, Zboralski D, Maasch C, Rosin N, Wierda W, Keating M, Kruschinski A, Burger J
Blood, 2013-11-25;123(7):1032-9.
Applications: Bioassay -
PCaAnalyser: a 2D-image analysis based module for effective determination of prostate cancer progression in 3D culture.
Authors: Hoque, Md Tamji, Windus, Louisa C, Lovitt, Carrie J, Avery, Vicky M
PLoS ONE, 2013-11-20;8(11):e79865.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Oligomannurarate sulfate inhibits CXCL12/SDF-1-mediated proliferation and invasion of human tumor cells in vitro.
Authors: Wen W, Xie S, Xin X, Geng M, Ding J, Chen Y
Acta Pharmacol Sin, 2013-10-21;34(12):1554-9.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Impaired endothelial progenitor cell mobilization and dysfunctional bone marrow stroma in diabetes mellitus.
Authors: Westerweel, Peter E, Teraa, Martin, Rafii, Shahin, Jaspers, Janneke, White, Ian A, Hooper, Andrea T, Doevendans, Pieter A, Verhaar, Marianne
PLoS ONE, 2013-03-28;8(3):e60357.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses.
Authors: Cheng, Cheng-Ch, Chang, Shing-Jy, Chueh, Yu-Neng, Huang, Tse-Shun, Huang, Po-Hsun, Cheng, Shu-Meng, Tsai, Tsung-Ne, Chen, Jaw-Wen, Wang, Hsei-Wei
BMC Genomics, 2013-03-15;14(0):182.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation.
Authors: Akimoto, Keiko, Kimura, Kenichi, Nagano, Masumi, Takano, Shingo, To'a Salazar, Georgina, Yamashita, Toshihar, Ohneda, Osamu
Stem Cells Dev, 2013-02-04;22(9):1370-86.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration.
Authors: Rossi E, Sanz-Rodriguez F, Eleno N, Duwell A, Blanco F, Langa C, Botella L, Cabanas C, Lopez-Novoa J, Bernabeu C
Blood, 2012-10-16;121(2):403-15.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia.
BMC Cancer, 2012-09-26;12(0):431.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
Authors: Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J
Nature, 2012-07-26;487(7408):505-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma.
Authors: Tai Y, Chang B, Kong S, Fulciniti M, Yang G, Calle Y, Hu Y, Lin J, Zhao J, Cagnetta A, Cea M, Sellitto M, Zhong M, Wang Q, Acharya C, Carrasco D, Buggy J, Elias L, Treon S, Matsui W, Richardson P, Munshi N, Anderson K
Blood, 2012-06-11;120(9):1877-87.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Authors: Badr G, Lefevre EA, Mohany M
PLoS ONE, 2011-09-01;6(9):e23741.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Structural basis of digoxin that antagonizes RORgamma t receptor activity and suppresses Th17 cell differentiation and interleukin (IL)-17 production.
Authors: Fujita-Sato S, Ito S, Isobe T, Ohyama T, Wakabayashi K, Morishita K, Ando O, Isono F
J. Biol. Chem., 2011-07-06;286(36):31409-17.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Stromal cell-derived factor-1 enhances distraction osteogenesis-mediated skeletal tissue regeneration through the recruitment of endothelial precursors.
Authors: Fujio M, Yamamoto A, Ando Y, Shohara R, Kinoshita K, Kaneko T, Hibi H, Ueda M
Bone, 2011-06-29;49(4):693-700.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer.
Authors: Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, Tacheuchi S, Mouri H, Yamashita K, Ohtsubo K, Yano S
Clin. Cancer Res., 2011-04-11;17(11):3619-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1alpha/CXCL12 in the brain.
Authors: Benamar K, Palma J, Cowan A, Geller EB, Adler MW
Drug Alcohol Depend, 2010-11-26;114(2):246-8.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo -
Delay of migrating leukocytes by the basement membrane deposited by endothelial cells in long-term culture.
Authors: Burton VJ, Butler LM, McGettrick HM, Stone PC, Jeffery HC, Savage CO, Rainger GE, Nash GB
Exp. Cell Res., 2010-11-04;317(3):276-92.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCR7 protein is not expressed on human or mouse leukocytes.
Authors: Berahovich RD, Zabel BA, Penfold ME, Lewen S, Wang Y, Miao Z, Gan L, Pereda J, Dias J, Slukvin II, McGrath KE, Jaen JC, Schall TJ
J. Immunol., 2010-10-01;185(9):5130-9.
Species: Human
Sample Types: Whole Cells
Applications: Binding Assay -
Implication of discoidin domain receptor 1 in T cell migration in three-dimensional collagen.
Authors: Hachehouche LN, Chetoui N, Aoudjit F
Mol. Immunol., 2010-03-29;47(9):1866-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of circulating dendritic cells in melanoma: role of CCR6 in plasmacytoid dendritic cell recruitment to the tumor.
Authors: Charles J, Di Domizio J, Salameire D, Bendriss-Vermare N, Aspord C, Muhammad R, Lefebvre C, Plumas J, Leccia MT, Chaperot L
J. Invest. Dermatol., 2010-03-11;130(6):1646-56.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization.
Authors: Sengupta N, Afzal A, Caballero S, Chang KH, Shaw LC, Pang JJ, Bond VC, Bhutto I, Baba T, Lutty GA, Grant MB
Invest. Ophthalmol. Vis. Sci., 2009-12-10;51(5):2697-704.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation.
Authors: Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE
Blood, 2009-10-12;114(24):5091-101.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9.
Authors: Kenig S, Alonso MB, Mueller MM, Lah TT
Cancer Lett., 2009-08-22;289(1):53-61.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy.
Authors: Zhu Y, Vergote D, Pardo C, Noorbakhsh F, McArthur JC, Hollenberg MD, Overall CM, Power C
FASEB J., 2009-04-20;23(9):2928-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.
Authors: Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R
J. Exp. Med., 2009-03-09;206(3):535-48.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin.
Authors: Skrzeczynska-Moncznik J, Wawro K, Stefanska A, Oleszycka E, Kulig P, Zabel BA, Sulkowski M, Kapinska-Mrowiecka M, Czubak-Macugowska M, Butcher EC, Cichy J
Biochem. Biophys. Res. Commun., 2009-01-23;380(2):323-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment.
Authors: Crawford Y, Kasman I, Yu L, Zhong C, Wu X, Modrusan Z, Kaminker J, Ferrara N
Cancer Cell, 2009-01-06;15(1):21-34.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4.
Authors: Struyf S, Noppen S, Loos T, Mortier A, Gouwy M, Verbeke H, Huskens D, Luangsay S, Parmentier M, Geboes K, Schols D, Van Damme J, Proost P
J. Immunol., 2009-01-01;182(1):666-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
J. Immunol., 2008-12-01;181(11):8053-67.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis.
Authors: Ouwehand K, Santegoets SJ, Bruynzeel DP, Scheper RJ, de Gruijl TD, Gibbs S
Eur. J. Immunol., 2008-11-01;38(11):3050-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo.
Authors: Kerfoot SM, Andonegui G, Bonder CS, Liu L
Am. J. Physiol. Heart Circ. Physiol., 2008-04-18;294(6):H2524-34.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
Nature, 2007-12-06;450(7171):825-31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells.
Authors: Kaminski A, Ma N, Donndorf P, Lindenblatt N, Feldmeier G, Ong LL, Furlani D, Skrabal CA, Liebold A, Vollmar B, Steinhoff G
Lab. Invest., 2007-11-26;88(1):58-69.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo -
Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: identification of novel MSC subpopulations that respond to guidance cues in brain.
Authors: Isakova IA, Baker K, Dutreil M, Dufour J, Gaupp D, Phinney DG
Stem Cells, 2007-10-11;25(12):3261-70.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay -
iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity.
Authors: Meyer EH, Wurbel MA, Staton TL, Pichavant M, Kan MJ, Savage PB, DeKruyff RH, Butcher EC, Campbell JJ, Umetsu DT
J. Immunol., 2007-10-01;179(7):4661-71.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.
Authors: Park EJ, Mora JR, Carman CV, Chen J, Sasaki Y, Cheng G, von Andrian UH, Shimaoka M
J. Clin. Invest., 2007-09-01;117(9):2526-38.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells.
Authors: Bayry J, Triebel F, Kaveri SV, Tough DF
J. Immunol., 2007-04-01;178(7):4184-93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
Authors: Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P
AIDS, 2007;21(10):1263-72.
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard) -
HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
Authors: Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
Glia, 2006-11-01;54(6):619-29.
Applications: ELISA (Standard) -
FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc.
Authors: Nakayama T, Mutsuga N, Tosato G
Blood, 2006-10-31;109(4):1363-72.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm.
Authors: Schreiber TH, Shinder V, Cain DW, Alon R, Sackstein R
Blood, 2006-10-12;109(4):1381-6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3.
Authors: Saunders WB, Bohnsack BL, Faske JB, Anthis NJ, Bayless KJ, Hirschi KK, Davis GE
J. Cell Biol., 2006-10-09;175(1):179-91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54.
Authors: Lisignoli G, Cristino S, Piacentini A, Cavallo C, Caplan AI, Facchini A
J. Cell. Physiol., 2006-05-01;207(2):364-73.
Applications: ELISA (Standard) -
Novel antiviral activity of chemokines.
Authors: Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, Nagakubo D, Saito T, Shimomura Y, Yoshie O
Virology, 2006-04-17;350(2):484-92.
Species: Virus
Sample Types: Virus, Whole Cells
Applications: Binding Assay, Bioassay -
Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells.
Authors: Infantino S, Moepps B, Thelen M
J. Immunol., 2006-02-15;176(4):2197-207.
Applications: ELISA (Standard) -
Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles.
Authors: Anghelina M, Krishnan P, Moldovan L, Moldovan NI
Am. J. Pathol., 2006-02-01;168(2):529-41.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism.
Authors: Carr AN, Howard BW, Yang HT, Eby-Wilkens E, Loos P, Varbanov A, Qu A, DeMuth JP, Davis MG, Proia A, Terjung RL, Peters KG
Cardiovasc. Res., 2006-01-10;69(4):925-35.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo -
Multipotentiality, homing properties, and pyramidal neurogenesis of CNS-derived LeX(ssea-1)+/CXCR4+ stem cells.
Authors: Corti S, Locatelli F, Papadimitriou D, Donadoni C, Del Bo R, Fortunato F, Strazzer S, Salani S, Bresolin N, Comi GP
FASEB J., 2005-09-08;19(13):1860-2.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus.
Authors: Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B
Arthritis Rheum., 2005-05-01;52(5):1504-16.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.
Authors: Curiel, Tyler J, Coukos, George, Zou, Linhua, Alvarez, Xavier, Cheng, Pui, Mottram, Peter, Evdemon-Hogan, Melina, Conejo-Garcia, Jose R, Zhang, Lin, Burow, Matthew, Zhu, Yun, Wei, Shuang, Kryczek, Ilona, Daniel, Ben, Gordon, Alan, Myers, Leann, Lackner, Andrew, Disis, Mary L, Knutson, Keith L, Chen, Lieping, Zou, Weiping
Nat Med, 2004-08-22;10(9):942-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of hematopoietic progenitor mobilization in protease-deficient mice.
Authors: Levesque JP, Liu F, Simmons PJ, Betsuyaku T, Senior RM, Pham C, Link DC
Blood, 2004-03-09;104(1):65-72.
Applications: ELISA (Standard) -
HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis.
Authors: Janardhan A, Swigut T, Hill B, Myers MP, Skowronski J
PLoS Biol., 2004-01-20;2(1):E6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Development of a novel surrogate virus for human T-cell leukemia virus type 1: inhibition of infection by osteoprotegerin.
Authors: Okuma K, Dalton KP, Buonocore L, Ramsburg E, Rose JK
J. Virol., 2003-08-01;77(15):8562-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo.
Authors: Villalba S, Salvucci O, Aoki Y, De La Luz Sierra M, Gupta G, Davis D, Wyvill K, Little R, Yarchoan R, Tosato G
J. Leukoc. Biol., 2003-07-22;74(5):880-8.
Species: Human, Mouse
Sample Types: N/A, Whole Cells
Applications: Bioassay, Control, ELISA (Standard), Western Blot -
Expression of functional CCR and CXCR chemokine receptors in podocytes.
Authors: Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H
J. Immunol., 2002-06-15;168(12):6244-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.
Authors: Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S
Cell, 2002-05-31;109(5):625-37.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes.
Authors: Zamarchi R, 2019, Allavena P, Borsetti A, Stievano L, Tosello V, Marcato N, Esposito G, Roni V, Paganin C, Bianchi G, Titti F, Verani P, Gerosa G, Amadori A
192, 2002-02-01;127(2):321-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A CD4-independent interaction of human immunodeficiency virus-1 gp120 with CXCR4 induces their cointernalization, cell signaling, and T-cell chemotaxis.
Authors: Misse D, Cerutti M, Noraz N, Jourdan P, Favero J, Devauchelle G, Yssel H, Taylor N, Veas F
Blood, 1999-04-15;93(8):2454-62.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay
FAQs
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Does Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Protein (Catalog # 350-NS or Catalog # 350-NS/CF) contain any tags?
Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha Protein (Catalog # 350-NS or Catalog # 350-NS/CF) does not contain any tags. Please refer to the Source section on the product-specific page for sequence information.
Reviews for Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha
Average Rating: 4.8 (Based on 4 Reviews)
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