Recombinant Human MMP-9 Western Blot Standard Protein Summary
Product Specifications
Product Datasheets
WBC018
WBC018
Formulation | No With Carrier Product Bottling Info |
Reconstitution | Resuspend the lyophilized powder in 250 uL SDS-PAGE sample buffer. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
Background: MMP-9
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
Citations for Recombinant Human MMP-9 Western Blot Standard Protein
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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Matrix metallopeptidase expression and modulation by transforming growth factor-beta1 in equine endometrosis
Authors: A Szóstek-Mi, M S?owi?ska, J Pacewicz, DJ Skarzynski, K Okuda
Sci Rep, 2020-01-24;10(1):1119.
Species: Human
Sample Types: Protein
Applications: Reference Standard -
Two-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuries.
Authors: Chen, Shanyan, Meng, Fanjun, Chen, Zhenzhou, Tomlinson, Brittany, Wesley, Jennifer, Sun, Grace Y, Whaley-Connell, Adam T, Sowers, James R, Cui, Jiankun, Gu, Zezong
PLoS ONE, 2015-04-10;10(4):e0123852.
Species: Human
Sample Types: Whole Cells
Applications: Zymography -
12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor.
Authors: Liu M, Saeki K, Matsunobu T, Okuno T, Koga T, Sugimoto Y, Yokoyama C, Nakamizo S, Kabashima K, Narumiya S, Shimizu T, Yokomizo T
J Exp Med, 2014-05-12;211(6):1063-78.
Species: Human
Sample Types: Whole Cells
Applications: Zymography
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