Recombinant Human IL-2 Protein

C5a enhances inflammation and chemotaxis of ?? T cells in malignant pleural effusion
Authors: Deng, S;Jiang, Y;Luo, L;Tang, H;Hu, X;Wu, C;Tang, J;Ge, H;Gong, X;Cai, R;Wang, G;Li, X;Feng, J;
International immunopharmacology
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Nicotinamide mononucleotide impacts HIV-1 infection by modulating immune activation in T lymphocytes and humanized mice
Authors: Mo, Y;Yue, M;Yim, LY;Zhou, R;Yu, C;Peng, Q;Zhou, Y;Luk, TY;Lui, GC;Huang, H;Lim, CYH;Wang, H;Liu, L;Sun, H;Wang, J;Song, Y;Chen, Z;
EBioMedicine
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dynamic establishment and maintenance of the human intestinal B cell population and repertoire following transplantation
Authors: Fu, J;Hsiao, T;Waffarn, E;Meng, W;Long, KD;Frangaj, K;Jones, R;Gorur, A;Shtewe, A;Li, M;Muntnich, CB;Rogers, K;Jiao, W;Velasco, M;Matsumoto, R;Kubota, M;Wells, S;Danzl, N;Ravella, S;Iuga, A;Vasilescu, ER;Griesemer, A;Weiner, J;Farber, DL;Luning Prak, ET;Martinez, M;Kato, T;Hershberg, U;Sykes, M;
medRxiv : the preprint server for health sciences
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Single-cell analysis of immune recognition in chronic myeloid leukemia patients following tyrosine kinase inhibitor discontinuation
Authors: Huuhtanen, J;Adnan-Awad, S;Theodoropoulos, J;Forstén, S;Warfvinge, R;Dufva, O;Bouhlal, J;Dhapola, P;Duàn, H;Laajala, E;Kasanen, T;Klievink, J;Ilander, M;Jaatinen, T;Olsson-Strömberg, U;Hjorth-Hansen, H;Burchert, A;Karlsson, G;Kreutzman, A;Lähdesmäki, H;Mustjoki, S;
Leukemia
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease
Authors: Vaikunthanathan, T;Landmann, E;Correa, DM;Romano, M;Trevelin, SC;Peng, Q;Crespo, E;Corrado, M;Lozano, JJ;Pearce, EL;Perpinan, E;Zoccarato, A;Siew, L;Edwards-Hicks, J;Khan, R;Luu, NT;Thursz, MR;Newsome, PN;Martinez-Llordella, M;Shah, N;Lechler, RI;Shah, AM;Sanchez-Fueyo, A;Lombardi, G;Safinia, N;
EBioMedicine
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-? axis
Authors: Ma, X;Wang, Q;Sun, C;Agarwal, I;Wu, H;Chen, J;Zhao, C;Qi, G;Teng, Q;Yuan, C;Yan, S;Peng, J;Li, R;Song, K;Zhang, Q;Kong, B;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Optimized conditions for gene transduction into primary immune cells using viral vectors
Authors: Kim, Y;Lee, DY;Choi, JU;Park, JS;Lee, SM;Kang, CH;Park, CH;
Scientific reports
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays
Authors: Kuzmichev, YV;Lackman-Smith, C;Bakkour, S;Wiegand, A;Bale, MJ;Musick, A;Bernstein, W;Aronson, N;Ake, J;Tovanabutra, S;Stone, M;Ptak, RG;Kearney, MF;Busch, MP;Wonderlich, ER;Kulpa, DA;
Scientific reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Opioid use does not limit potent low-dose HIV-1 latency reversal agent boosting
Authors: Lilie, T;Bouzy, J;Asundi, A;Taylor, J;Roche, S;Olson, A;Coxen, K;Corry, H;Jordan, H;Clayton, K;Lin, N;Tsibris, A;
medRxiv : the preprint server for health sciences
Species:  Human
Sample Types: Whole Cells
Applications: Bioassay

ITK signaling regulates a switch between T helper 17 and T regulatory cell lineages via a calcium-mediated pathway
Authors: O Anannya, W Huang, A August
bioRxiv : the preprint server for biology, 2023-04-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive Tumors
Authors: G Silva, AF Rodrigues, S Ferreira, C Matos, RP Eleutério, G Marques, K Kucheryava, AR Lemos, PMF Sousa, R Castro, A Barbas, D Simão, PM Alves
Biomolecules, 2023-03-02;13(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of a TGFbeta-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy
Authors: C Beck, NP Casey, I Persiconi, NN Moharrami, A Sike, Y Jin, JA Kyte
Biomedicines, 2023-02-04;11(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prevalent and immunodominant CD8 T�cell epitopes are conserved in SARS-CoV-2 variants
Authors: S Meyer, I Blaas, RC Bollineni, M Delic-Sara, TT Tran, C Knetter, KZ Dai, TS Madssen, JT Vaage, A Gustavsen, W Yang, LSH Nissen-Mey, K Douvlatani, M Laos, MM Nielsen, B Thiede, A Søraas, F Lund-Johan, EH Rustad, J Olweus
Cell Reports, 2023-01-09;42(1):111995.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation
Authors: R Boytz, S Seitz, E Gaudiano, JJ Patten, PT Keiser, JH Connor, AH Sharpe, RA Davey
Viruses, 2022-12-23;15(1):.
Species: Complex Species Category
Sample Types: Cell Culture Supernates
Applications: Bioassay

An alphavbeta3 integrin checkpoint is critical for efficient TH2 cell cytokine polarization and potentiation of antigen-specific immunity
Authors: ACH Szeto, ACF Ferreira, J Mannion, PA Clark, M Sivasubram, MWD Heycock, A Crisp, HE Jolin, P Kozik, MD Knolle, ANJ McKenzie
Nature Immunology, 2022-12-22;24(1):123-135.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D
Authors: MJ Lee, MW Leong, A Rustagi, A Beck, L Zeng, S Holmes, LS Qi, CA Blish
Cell Reports, 2022-12-12;41(13):111892.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity
Authors: E Cruz-Loren, NP Ramirez, J Lee, S Pandhe, L Wang, J Hernandez-, AM Spivak, V Planelles, T Petersen, MK Jain, ED Martinez, I D'Orso
Viruses, 2022-10-18;14(10):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Notch2-dependent GATA3+ Treg cells alleviate allergic rhinitis by suppressing the Th2 cell response
Authors: WE Jiao, S Xu, YL Qiao, YG Kong, L Sun, YQ Deng, R Yang, ZZ Tao, QQ Hua, SM Chen
International immunopharmacology, 2022-09-22;112(0):109261.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells.
Authors: Somasundaram A, Cillo A, Lampenfeld C, Workman C, Kunning S, Oliveri L, Velez M, Joyce S, Calderon M, Dadey R, Rajasundaram D, Normolle D, Watkins S, Herman J, Kirkwood J, Lipson E, Ferris R, Bruno T, Vignali D
Cancer Immunol Res, 2022-07-01;10(7):885-899.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Antiviral Activities of HIV-1-Specific Human Broadly Neutralizing Antibodies Are Isotype-Dependent
Authors: B Noailly, M Yaugel-Nov, J Werquin, F Jospin, D Drocourt, T Bourlet, N Rochereau, S Paul
Vaccines, 2022-06-06;10(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Short treatment of peripheral blood cells product with Fas ligand using closed automated cell processing system significantly reduces immune cell reactivity of the graft in vitro and in vivo
Authors: G Rodionov, M Rosenzwaig, MS Tzadok, M Kvint, E Gevir, E Zorde-Khva, A Peled, S Yarkoni, A Ofer
Bone marrow transplantation, 2022-05-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel Compound Inhibitors of HIV-1NL4-3 Vpu
Authors: CA Robinson, TD Lyddon, HM Gil, DT Evans, YV Kuzmichev, J Richard, A Finzi, S Welbourn, L Rasmussen, NM Nebane, VV Gupta, S Ananthan, Z Cai, ER Wonderlich, CE Augelli-Sz, R Bostwick, RG Ptak, SM Schader, MC Johnson
Viruses, 2022-04-15;14(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T cell migration potentiates HIV infection by enhancing viral fusion and integration
Authors: P Lopez, O Ajibola, A Pagliuzza, R Zayats, WH Koh, A Herschhorn, N Chomont, TT Murooka
Cell Reports, 2022-02-22;38(8):110406.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

c-Met-Specific Chimeric Antigen Receptor T Cells Demonstrate Anti-Tumor Effect in c-Met Positive Gastric Cancer
Authors: CH Kang, Y Kim, DY Lee, SU Choi, HK Lee, CH Park
Cancers, 2021-11-16;13(22):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Small molecule allosteric inhibitors of RORgammat block Th17-dependent inflammation and associated gene expression in vivo
Authors: SA Saenz, A Local, T Carr, A Shakya, S Koul, H Hu, L Chourb, J Stedman, J Malley, LA D'Agostino, V Shanmugasu, J Malona, CE Schwartz, L Beebe, M Clements, G Rajaraman, J Cho, L Jiang, A Dubrovskiy, M Kreilein, R Shimanovic, LG Hamann, L Escoubet, JM Ellis
PLoS ONE, 2021-11-09;16(11):e0248034.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The small intestine epithelium exempts Foxp3+ Tregs from their IL-2 requirement for homeostasis and effector function
Authors: P Prakhar, J Alvarez-De, H Keller, A Crossman, X Tai, YK Park, JH Park
JCI Insight, 2021-11-08;6(21):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Changes in circulating exosome molecular profiles following surgery/(chemo)radiotherapy: early detection of response in head and neck cancer patients
Authors: MN Theodoraki, S Laban, EK Jackson, R Lotfi, PJ Schuler, C Brunner, TK Hoffmann, TL Whiteside, L Hofmann
British Journal of Cancer, 2021-10-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2pos subjects
Authors: S Yu, C Di, S Chen, M Guo, J Yan, Z Zhu, L Liu, R Feng, Y Xie, R Zhang, J Chen, M Wang, D Wei, H Fang, T Yin, J Huang, S Chen, H Lu, J Zhu, J Qu
Cell Research, 2021-09-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease
Authors: L Dai, Q Wang, X Lv, F Gao, Z Chen, Y Shen
Brain, Behavior, and Immunity, 2021-09-06;98(0):337-348.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Anaphylatoxins orchestrate Th17 response via interactions between CD16+ monocytes and pleural mesothelial cells in tuberculous pleural effusion
Authors: S Deng, X Hu, L Luo, W Tang, Y Jiang, F Yin, C Hu, J Feng, X Li
PloS Neglected Tropical Diseases, 2021-07-08;15(7):e0009508.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma
Authors: HL Penny, JL Sieow, SY Gun, MC Lau, B Lee, J Tan, C Phua, F Toh, Y Nga, WH Yeap, B Janela, D Kumar, H Chen, J Yeong, JA Kenkel, A Pang, D Lim, HC Toh, TLK Hon, CI Johnson, HJ Khameneh, A Mortellaro, EG Engleman, O Rotzschke, F Ginhoux, JP Abastado, J Chen, SC Wong
International Journal of Molecular Sciences, 2021-06-14;22(12):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma
Authors: N Oishi, T Hundal, JL Phillips, S Dasari, G Hu, DS Viswanatha, R He, M Mai, HK Jacobs, NH Ahmed, SI Syrbu, Y Salama, JR Chapman, F Vega, J Sidhu, NN Bennani, AL Epstein, LJ Medeiros, MW Clemens, RN Miranda, AL Feldman
Haematologica, 2021-06-01;0(0):.
Species: Xenograft
Sample Types: Whole Cells
Applications: Bioassay

Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells
Authors: ED Rossignol, AS Dugast, H Compere, CA Cottrell, J Copps, S Lin, D Cizmeci, MS Seaman, ME Ackerman, AB Ward, G Alter, B Julg
Cell Reports, 2021-05-25;35(8):109167.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling cell-specific dynamics and regulation of the common gamma chain cytokines
Authors: AM Farhat, AC Weiner, C Posner, ZS Kim, B Orcutt-Jah, SM Carlson, AS Meyer
Cell Reports, 2021-04-27;35(4):109044.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Complement Inactivation Strategy of Staphylococcus aureus Using Decay-Accelerating Factor and the Response of Infected HaCaT Cells
Authors: KO Jang, YW Lee, H Kim, DK Chung
International Journal of Molecular Sciences, 2021-04-13;22(8):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

CD6 is a target for cancer immunotherapy
Authors: JH Ruth, M Gurrea-Rub, KS Athukorala, SM Rasmussen, D Weber, PM Randon, RJ Gedert, ME Lind, MA Amin, PL Campbell, PS Tsou, Y Mao-Draaye, Q Wu, TM Lanigan, VG Keshamouni, NG Singer, F Lin, DA Fox
JCI Insight, 2021-03-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
Authors: AT Tan, M Linster, CW Tan, N Le Bert, WN Chia, K Kunasegara, Y Zhuang, CYL Tham, A Chia, GJD Smith, B Young, S Kalimuddin, JGH Low, D Lye, LF Wang, A Bertoletti
Cell Reports, 2021-01-21;34(6):108728.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

B7-H3 Chimeric Antigen Receptor Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma
Authors: Z Zi, H Zhao, H Wang, X Ma, F Wei
Cancers, 2020-12-17;12(12):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Anti-tumour immunity induces aberrant peptide presentation in melanoma
Authors: O Bartok, A Pataskar, R Nagel, M Laos, E Goldfarb, D Hayoun, R Levy, PR Körner, IZM Kreuger, J Champagne, EA Zaal, OB Bleijervel, X Huang, J Kenski, J Wargo, A Brandis, Y Levin, O Mizrahi, M Alon, S Lebon, W Yang, MM Nielsen, N Stern-Gino, M Altelaar, CR Berkers, T Geiger, DS Peeper, J Olweus, Y Samuels, R Agami
Nature, 2020-12-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds
Authors: S Campinoti, A Gjinovci, R Ragazzini, L Zanieri, L Ariza-McNa, M Catucci, S Boeing, JE Park, JC Hutchinson, M Muñoz-Ruiz, PG Manti, G Vozza, CE Villa, DE Phylactopo, C Maurer, G Testa, HJ Stauss, SA Teichmann, NJ Sebire, AC Hayday, D Bonnet, P Bonfanti
Nature Communications, 2020-12-11;11(1):6372.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Identification of unrecognized host factors promoting HIV-1 latency
Authors: Z Li, C Hajian, WC Greene
PloS Pathogens, 2020-12-03;16(12):e1009055.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Shared Immunogenic Poly-Epitope Frameshift Mutations in Microsatellite Unstable Tumors.
Authors: Roudko V, Bozkus C, Orfanelli T, McClain C, Carr C, O'Donnell T, Chakraborty L, Samstein R, Huang K, Blank S, Greenbaum B, Bhardwaj N
Cell, 2020-11-30;183(6):1634-1649.e17.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans
Authors: KK Naidoo, ZB Shangase, T Rashid, A Ngubane, N Ismail, T Ndung'u, CF Thobakgale
PLoS ONE, 2020-11-19;15(11):e0242448.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional Interactions of Common Allotypes of Rhesus Macaque Fc&gammaR2A and Fc&gammaR3A with Human and Macaque IgG Subclasses
Authors: MW Grunst, AG Grandea, SK Janaka, I Hammad, P Grimes, JA Karl, R Wiseman, DH O'Connor, DT Evans
J Immunol, 2020-11-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Plasmodium sporozoites induce regulatory macrophages
Authors: BMF Winkel, LR Pelgrom, R van Schuij, E Baalbergen, MS Ganesh, H Gerritsma, CM de Korne, N Duszenko, MCC Langenberg, SC Chevalley-, HH Smits, EC de Jong, B Everts, B Franke-Fay, M Roestenber
PLoS Pathog., 2020-09-08;16(9):e1008799.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

CD154 inhibits death of T cells via a Cis interaction with the alpha5beta1 integrin
Authors: M Bachsais, S Salti, K Zaoui, GS Hassan, F Aoudjit, W Mourad
PLoS ONE, 2020-08-03;15(8):e0235753.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Immune Suppressive Effects of Plasma-Derived Exosome Populations in Head and Neck Cancer
Authors: IJ Beccard, L Hofmann, JC Schroeder, S Ludwig, S Laban, C Brunner, R Lotfi, TK Hoffmann, EK Jackson, PJ Schuler, MN Theodoraki
Cancers (Basel), 2020-07-21;12(7):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation
Authors: J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham
Cell Rep, 2020-06-30;31(13):107820.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chromatin Priming Renders T Cell Tolerance-Associated Genes Sensitive to Activation below the�Signaling Threshold for Immune Response Genes
Authors: SL Bevington, STH Ng, GJ Britton, P Keane, DC Wraith, PN Cockerill
Cell Rep, 2020-06-09;31(10):107748.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NADPH oxidase 5&alpha promotes the formation of CD271 tumor-initiating cells in oral cancer
Authors: W Gao, S Xu, M Zhang, S Liu, SP Siu, H Peng, JC Ng, GS Tsao, AW Chan, VL Chow, JY Chan, TS Wong
Am J Cancer Res, 2020-06-01;10(6):1710-1727.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus
Authors: A Dharan, N Bachmann, S Talley, V Zwikelmaie, EM Campbell
Nat Microbiol, 2020-06-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hyperfunction of CD4 CD25 regulatory T cells in de novo acute myeloid leukemia
Authors: Y Wan, C Zhang, Y Xu, M Wang, Q Rao, H Xing, Z Tian, K Tang, Y Mi, Y Wang, J Wang
BMC Cancer, 2020-05-26;20(1):472.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

An Elvitegravir Nanoformulation Crosses the Blood-Brain Barrier and Suppresses HIV-1 Replication in Microglia
Authors: Y Gong, K Zhi, PKB Nagesh, N Sinha, P Chowdhury, H Chen, S Gorantla, MM Yallapu, S Kumar
Viruses, 2020-05-20;12(5):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics
Authors: K Froning, J Maguire, A Sereno, F Huang, S Chang, K Weichert, AJ Frommelt, J Dong, X Wu, H Austin, EM Conner, JR Fitchett, AR Heng, D Balasubram, MT Hilgers, B Kuhlman, SJ Demarest
Nat Commun, 2020-05-11;11(1):2330.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeting of CD38 by the tumor suppressor miR-26a serves as a novel potential therapeutic agent in multiple myeloma
Authors: Y Hu, H Liu, C Fang, C Li, F Xhyliu, H Dysert, J Bodo, G Habermehl, BE Russell, W Li, M Chappell, X Jiang, SL Ondrejka, ED Hsi, JP Maciejewsk, Q Yi, KC Anderson, NC Munshi, G Ao, JN Valent, J Lin, J Zhao
Cancer Res., 2020-03-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

In vitro model for the assessment of human immune responses to subunit RSV vaccines
Authors: T Chirkova, B Ha, BH Rimawi, AGP Oomens, TV Hartert, LJ Anderson
PLoS ONE, 2020-03-19;15(3):e0229660.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells
Authors: AE Morelli, TL Sumpter, DM Rojas-Cana, M Bandyopadh, Z Chen, O Tkacheva, WJ Shufesky, CT Wallace, SC Watkins, A Berger, CJ Paige, LD Falo, AT Larregina
Cell Rep, 2020-03-10;30(10):3448-3465.e8.
Species: Mouse
Sample Types: Dendritic Cells
Applications: Bioassay

Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages
Authors: J Lubow, MC Virgilio, M Merlino, DR Collins, M Mashiba, BG Peterson, Z Lukic, MM Painter, F Gomez-Rive, V Terry, G Zimmerman, KL Collins
Elife, 2020-03-02;9(0):.
Species: Human
Sample Types: Leukocytes
Applications: Bioassay

Novel elvitegravir nanoformulation for drug delivery across the blood-brain barrier to achieve HIV-1 suppression in the CNS macrophages
Authors: Y Gong, P Chowdhury, PKB Nagesh, MA Rahman, K Zhi, MM Yallapu, S Kumar
Sci Rep, 2020-03-02;10(1):3835.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

p38 MAPK signalling regulates cytokine production in IL-33 stimulated Type 2 Innate Lymphoid cells
Authors: T Petrova, J Pesic, K Pardali, M Gaestel, JSC Arthur
Sci Rep, 2020-02-26;10(1):3479.
Species: Human
Sample Types: Cells
Applications: Cell Culture

DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR
Authors: S Zicari, AL Sharma, G Sahu, L Dubrovsky, L Sun, H Yue, T Jada, A Ochem, G Simon, M Bukrinsky, M Tyagi
Oncotarget, 2020-02-18;11(7):699-726.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Developmental plasticity allows outside-in immune responses by resident memory T cells
Authors: R Fonseca, LK Beura, CF Quarnstrom, HE Ghoneim, Y Fan, CC Zebley, MC Scott, NJ Fares-Fred, S Wijeyesing, EA Thompson, H Borges da, V Vezys, B Youngblood, D Masopust
Nat. Immunol., 2020-02-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
Authors: PJ Metz, KA Ching, T Xie, P Delgado Cu, S Niessen, JH Tatlock, K Jensen-Per, BW Murray
Cell Rep, 2020-02-11;30(6):1935-1950.e8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide
Authors: SV Radhakrish, T Luetkens, SD Scherer, P Davis, ER Vander Mau, ML Olson, S Yousef, J Panse, Y Abdiche, KD Li, RR Miles, W Matsui, AL Welm, D Atanackovi
Nat Commun, 2020-02-07;11(1):798.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Immunological effects of adjuvants in subsets of antigen presenting cells of cancer patients undergoing chemotherapy
Authors: A Mauriello, C Manolio, B Cavalluzzo, A Avallone, M Borrelli, A Morabito, E Iovine, A Chambery, R Russo, ML Tornesello, FM Buonaguro, M Tagliamont, L Buonaguro
J Transl Med, 2020-01-23;18(1):34.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
Authors: JB McBrien, M Mavigner, L Franchitti, SA Smith, E White, GK Tharp, H Walum, K Busman-Suh, CR Aguilera-S, WO Thayer, RA Spagnuolo, M Kovarova, A Wahl, B Cervasi, DM Margolis, TH Vanderford, DG Carnathan, M Paiardini, JD Lifson, JH Lee, JT Safrit, SE Bosinger, JD Estes, CA Derdeyn, JV Garcia, DA Kulpa, A Chahroudi, G Silvestri
Nature, 2020-01-22;0(0):.
Species: Mouse
Sample Types: Whole Cell
Applications: Cell Culture

T cell receptor and cytokine signal integration in CD8+ T cells is mediated by the protein Themis
Authors: J Brzostek, N Gautam, X Zhao, EW Chen, M Mehta, DWH Tung, YL Chua, J Yap, SH Cho, S Sankaran, V Rybakin, G Fu, NRJ Gascoigne
Nat. Immunol., 2020-01-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease
Authors: D Gate, N Saligrama, O Leventhal, AC Yang, MS Unger, J Middeldorp, K Chen, B Lehallier, D Channappa, MB De Los San, A McBride, J Pluvinage, F Elahi, GK Tam, Y Kim, M Greicius, AD Wagner, L Aigner, DR Galasko, MM Davis, T Wyss-Coray
Nature, 2020-01-08;577(7790):399-404.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Defective glycosylation and multisystem abnormalities characterize the primary immunodeficiency XMEN disease
Authors: JC Ravell, M Matsuda-Le, SD Chauvin, J Zou, M Biancalana, SJ Deeb, S Price, HC Su, G Notarangel, P Jiang, A Morawski, C Kanellopou, KW Binder, R Mukherjee, JT Anibal, B Sellers, L Zheng, T He, AB George, S Pittaluga, A Powers, DE Kleiner, D Kapuria, M Ghany, S Hunsberger, JI Cohen, G Uzel, J Bergerson, L Wolfe, C Toro, W Gahl, LR Folio, H Matthews, P Angelus, IK Chinn, JS Orange, CM Trujillo-V, JL Franco, J Orrego-Ara, S Gutiérrez-, NC Patel, K Raymond, T Patiroglu, E Unal, M Karakukcu, AG Day, P Mehta, E Masutani, SS De Ravin, HL Malech, G Altan-Bonn, VK Rao, M Mann, MJ Lenardo
J. Clin. Invest., 2020-01-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
Authors: JJ Montoya, MA Turnidge, DH Wai, AR Patel, DW Lee, V Gokhale, LH Hurley, RJ Arceci, C Wetmore, DO Azorsa
BMC Cancer, 2019-12-27;19(1):1251.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The prognostic role of circulating CD8+ T cell proliferation in patients with untreated extensive stage small cell lung cancer
Authors: N An, H Wang, W Jia, W Jing, C Liu, H Zhu, J Yu
J Transl Med, 2019-12-03;17(1):402.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants
Authors: A Koenig, CC Chen, A Marçais, T Barba, V Mathias, A Sicard, M Rabeyrin, M Racapé, JP Duong-Van-, P Bruneval, A Loupy, S Dussurgey, S Ducreux, V Meas-Yedid, JC Olivo-Mari, H Paidassi, R Guillemain, JL Taupin, J Callemeyn, E Morelon, A Nicoletti, B Charreau, V Dubois, M Naesens, T Walzer, T Defrance, O Thaunat
Nat Commun, 2019-11-25;10(1):5350.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
Authors: M Yamagishi, M Hori, D Fujikawa, T Ohsugi, D Honma, N Adachi, H Katano, T Hishima, S Kobayashi, K Nakano, M Nakashima, M Iwanaga, A Utsunomiya, Y Tanaka, S Okada, K Tsukasaki, K Tobinai, K Araki, T Watanabe, K Uchimaru
Cell Rep, 2019-11-19;29(8):2321-2337.e7.
Species: Human
Sample Types: Whole Cell
Applications: Cell Culture

Efficacy of third-party chimeric antigen receptor modified peripheral blood natural killer cells for adoptive cell therapy of B-cell precursor acute lymphoblastic leukemia
Authors: C Quintarell, S Sivori, S Caruso, S Carlomagno, M Falco, I Boffa, D Orlando, M Guercio, Z Abbaszadeh, M Sinibaldi, S Di Cecca, A Camera, B Cembrola, A Pitisci, M Andreani, L Vinti, S Gattari, F Del Bufalo, M Algeri, G Li Pira, A Moseley, B De Angelis, L Moretta, F Locatelli
Leukemia, 2019-11-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

High-throughput compound screen reveals mTOR inhibitors as potential therapeutics to reduce (auto)antibody production by human plasma cells
Authors: P Tuijnenbur, DJ Aan de Ker, MH Jansen, B Morris, C Lieftink, RL Beijersber, EMM van Leeuwe, TW Kuijpers
Eur. J. Immunol., 2019-11-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Crystal structure of suboptimal viral fragments of Epstein Barr Virus Rta peptide-HLA complex that stimulate CD8 T cell response
Authors: X Huan, Z Zhuo, Z Xiao, EC Ren
Sci Rep, 2019-11-13;9(1):16660.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

The intestinal expansion of TCRγδ+ and disappearance of IL4+ T cells suggest their involvement in the evolution from potential to overt celiac disease
Authors: S Vitale, V Santarlasc, A Camarca, S Picascia, AD Pasquale, M Maglio, E Maggi, L Cosmi, F Annunziato, R Troncone, R Auricchio, C Gianfrani
Eur. J. Immunol., 2019-10-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3)
Authors: F Caccuri, A Bugatti, S Corbellini, S Roversi, A Zani, P Mazzuca, S Marsico, A Caruso, C Giagulli
Int J Mol Sci, 2019-10-24;20(21):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals
Authors: ER Wonderlich, K Subramania, B Cox, A Wiegand, C Lackman-Sm, MJ Bale, M Stone, R Hoh, MF Kearney, F Maldarelli, SG Deeks, MP Busch, RG Ptak, DA Kulpa
PLoS Pathog., 2019-10-14;15(10):e1008074.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Internal Ribosome Entry Site Dramatically Reduces Transgene Expression in Hematopoietic Cells in a Position-Dependent Manner
Authors: Q Zheng, X Zhang, H Yang, J Xie, Y Xie, J Chen, C Yu, C Zhong
Viruses, 2019-10-08;11(10):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming
Authors: AP Bénéchet, G De Simone, P Di Lucia, F Cilenti, G Barbiera, N Le Bert, V Fumagalli, E Lusito, F Moalli, V Bianchessi, F Andreata, P Zordan, E Bono, L Giustini, WV Bonilla, C Bleriot, K Kunasegara, G Gonzalez-A, DD Pinschewer, PTF Kennedy, L Naldini, M Kuka, F Ginhoux, A Cantore, A Bertoletti, R Ostuni, LG Guidotti, M Iannacone
Nature, 2019-10-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity
Authors: MW LaFleur, TH Nguyen, MA Coxe, BC Miller, KB Yates, JE Gillis, DR Sen, EF Gaudiano, R Al Abosy, GJ Freeman, WN Haining, AH Sharpe
Nat. Immunol., 2019-09-16;20(10):1335-1347.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Engineered triple inhibitory receptor resistance improves anti-tumor CAR-T cell performance via CD56
Authors: F Zou, L Lu, J Liu, B Xia, W Zhang, Q Hu, W Liu, Y Zhang, Y Lin, S Jing, M Huang, B Huang, B Liu, H Zhang
Nat Commun, 2019-09-11;10(1):4109.
Species: Human
Sample Types: Whole Cells
Applications: CAR-T (Bioassay)

CD4+ T cell activation and associated susceptibility to HIV-1 infection in vitro increased following acute resistance exercise in human subjects
Authors: AK Holbrook, HD Peterson, SA Bianchi, BW Macdonald, EC Bredahl, M Belshan, JA Siedlik
Physiol Rep, 2019-09-01;7(18):e14234.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA?155 inhibits the proliferation of CD8+ T�cells via upregulating regulatory T cells in vitiligo
Authors: M Lv, Z Li, J Liu, F Lin, Q Zhang, Z Li, Y Wang, K Wang, Y Xu
Mol Med Rep, 2019-08-23;20(4):3617-3624.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HLA-DQA1 and HLA-DQB1 Alleles, Conferring Susceptibility to Celiac Disease and Type 1 Diabetes, are More Expressed Than Non-Predisposing Alleles and are Coordinately Regulated
Authors: F Farina, S Picascia, L Pisapia, P Barba, S Vitale, A Franzese, E Mozzillo, C Gianfrani, G Del Pozzo
Cells, 2019-07-19;8(7):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pretreatment of Glioblastoma with Bortezomib Potentiates Natural Killer Cell Cytotoxicity through TRAIL/DR5 Mediated Apoptosis and Prolongs Animal Survival
Authors: A Gras Navar, H Espedal, JV Joseph, L Trachsel-M, M Bahador, B Tore Gjert, E Klæboe Kri, A Simonsen, H Miletic, P Øyvind Eng, MA Rahman, M Chekenya
Cancers (Basel), 2019-07-17;11(7):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells
Authors: KB Jung, O Kwon, MO Lee, H Lee, YS Son, O Habib, JH Oh, HS Cho, CR Jung, J Kim, MY Son
J Clin Med, 2019-07-04;8(7):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Significance of IL-17A-producing CD8+CD103+ skin resident memory T cells in psoriasis lesion and their possible relationship to clinical course
Authors: K Kurihara, T Fujiyama, P Phadungsak, T Ito, Y Tokura
J. Dermatol. Sci., 2019-06-20;95(1):21-27.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

CBP/p300 drives the differentiation of Regulatory T cells through transcriptional and non-transcriptional mechanisms
Authors: J Castillo, E Wu, C Lowe, S Srinivasan, R McCord, MC Wagle, S Jayakar, M Gonzalez E, J Eastham-An, B Liu, KE Hutchinson, W Jones, MP Stokes, SS Tarighat, T Holcomb, A Glibicky, FA Romero, S Magnuson, SA Huang, V Plaks, JM Giltnane, MR Lackner, Z Mounir
Cancer Res., 2019-06-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Downregulation of CD73 associates with T cell exhaustion in AML patients
Authors: Y Kong, B Jia, C Zhao, DF Claxton, A Sharma, C Annageldiy, JS Fotos, H Zeng, RF Paulson, KS Prabhu, H Zheng
J Hematol Oncol, 2019-04-24;12(1):40.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Immunogenic neoantigens derived from gene fusions stimulate T cell responses
Authors: W Yang, KW Lee, RM Srivastava, F Kuo, C Krishna, D Chowell, V Makarov, D Hoen, MG Dalin, L Wexler, R Ghossein, N Katabi, Z Nadeem, MA Cohen, SK Tian, N Robine, K Arora, H Geiger, P Agius, N Bouvier, K Huberman, K Vanness, JJ Havel, JS Sims, RM Samstein, R Mandal, J Tepe, I Ganly, AL Ho, N Riaz, RJ Wong, N Shukla, TA Chan, LGT Morris
Nat. Med., 2019-04-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Infiltration of T Cells into a Three-Dimensional Psoriatic Skin Model Mimics Pathological Key Features
Authors: I Lorthois, M Simard, S Morin, R Pouliot
Int J Mol Sci, 2019-04-03;20(7):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine
Authors: S Fourati, SP Ribeiro, F Blasco Tav, A Talla, F Lefebvre, M Cameron, J Kaewkungwa, P Pitisuttit, S Nitayaphan, S Rerks-Ngar, JH Kim, R Thomas, PB Gilbert, GD Tomaras, RA Koup, NL Michael, MJ McElrath, R Gottardo, RP Sékaly
Nat Commun, 2019-02-20;10(1):863.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb
Authors: MD Shortridge, PT Wille, AN Jones, A Davidson, J Bogdanovic, E Arts, J Karn, JA Robinson, G Varani
Nucleic Acids Res., 2019-02-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Negligible Effect of Sodium Chloride on the Development and Function of TGF-?-Induced CD4+ Foxp3+ Regulatory T Cells
Authors: Y Luo, Y Xue, J Wang, J Dang, Q Fang, G Huang, N Olsen, SG Zheng
Cell Rep, 2019-02-12;26(7):1869-1879.e3.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation
Authors: L Herviou, M Jourdan, AM Martinez, G Cavalli, J Moreaux
Leukemia, 2019-02-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Preconditioning human natural killer cells with chorionic villous mesenchymal stem cells stimulates their expression of inflammatory and anti-tumor molecules
Authors: MH Abumaree, NA Alshehri, A Almotery, AM Al Subayyi, E Bahattab, FM Abomaray, T Khatlani, B Kalionis, D Jawdat, MF El-Muzaini, MA Al Jumah, AS AlAskar
Stem Cell Res Ther, 2019-02-06;10(1):50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SA-49, a novel aloperine derivative, induces MITF-dependent lysosomal degradation of PD-L1
Authors: N Zhang, Y Dou, L Liu, X Zhang, X Liu, Q Zeng, Y Liu, M Yin, X Liu, H Deng, D Song
EBioMedicine, 2019-01-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BCR-associated factors driving chronic lymphocytic leukemia cells proliferation ex vivo
Authors: C Schleiss, W Ilias, O Tahar, Y Güler, L Miguet, C Mayeur-Rou, L Mauvieux, LM Fornecker, E Toussaint, R Herbrecht, F Bertrand, M Maumy-Bert, T Martin, S Fournel, P Georgel, S Bahram, L Vallat
Sci Rep, 2019-01-24;9(1):701.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8+ T-cell Function
Authors: S Whelan, E Ophir, MF Kotturi, O Levy, S Ganguly, L Leung, I Vaknin, S Kumar, L Dassa, K Hansen, D Bernados, B Murter, A Soni, JM Taube, AN Fader, TL Wang, IM Shih, M White, DM Pardoll, SC Liang
Cancer Immunol Res, 2019-01-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb
Authors: X Ma, T Yang, Y Luo, L Wu, Y Jiang, Z Song, T Pan, B Liu, G Liu, J Liu, F Yu, Z He, W Zhang, J Yang, L Liang, Y Guan, X Zhang, L Li, W Cai, X Tang, S Gao, K Deng, H Zhang
Elife, 2019-01-17;8(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Thymic regulatory T cells arise via two distinct developmental programs
Authors: DL Owen, SA Mahmud, LE Sjaastad, JB Williams, JA Spanier, DR Simeonov, R Ruscher, W Huang, I Proekt, CN Miller, C Hekim, JC Jeschke, P Aggarwal, U Broeckel, RS LaRue, CM Henzler, ML Alegre, MS Anderson, A August, A Marson, Y Zheng, CB Williams, MA Farrar
Nat. Immunol., 2019-01-14;20(2):195-205.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Indirubin modulates CD4+ T-cell homeostasis via PD1/PTEN/AKT signalling pathway in immune thrombocytopenia
Authors: Y Zhao, P Han, L Liu, X Wang, P Xu, H Wang, T Yu, Y Sun, L Li, T Sun, X Liu, H Zhou, J Qiu, L Wang, J Peng, S Xu, M Hou
J. Cell. Mol. Med., 2019-01-04;0(0):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mapping of ?/? T cells reveals V?2+ T cells resistance to senescence
Authors: W Xu, G Monaco, EH Wong, WLW Tan, H Kared, Y Simoni, SW Tan, WZY How, CTY Tan, BTK Lee, D Carbajo, S K G, ICH Low, EWH Mok, S Foo, J Lum, HL Tey, WP Tan, M Poidinger, E Newell, TP Ng, R Foo, AN Akbar, T Fülöp, A Larbi
EBioMedicine, 2018-12-07;39(0):44-58.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dysregulated NK cell PLC?2 signaling and activity in juvenile dermatomyositis
Authors: AA Throm, JB Alinger, JT Pingel, AL Daugherty, LM Pachman, AR French
JCI Insight, 2018-11-15;3(22):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Substrate-independent immunomodulatory characteristics of mesenchymal stem cells in three-dimensional culture
Authors: J Li, T Chen, X Huang, Y Zhao, B Wang, Y Yin, Y Cui, Y Zhao, R Zhang, X Wang, Y Wang, J Dai
PLoS ONE, 2018-11-08;13(11):e0206811.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ring finger protein 31-mediated atypical ubiquitination stabilizes forkhead box P3 and thereby stimulates regulatory T-cell function
Authors: F Zhu, G Yi, X Liu, F Zhu, A Zhao, A Wang, R Zhu, Z Chen, B Zhao, S Fang, X Yu, R Lin, R Liang, D Li, W Zhao, Z Zhang, W Guo, S Zhang, S Ge, X Fan, G Zhao, B Li
J. Biol. Chem., 2018-11-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory
Authors: S Viaud, JSY Ma, IR Hardy, EN Hampton, B Benish, L Sherwood, V Nunez, CJ Ackerman, E Khialeeva, M Weglarz, SC Lee, AK Woods, TS Young
Proc. Natl. Acad. Sci. U.S.A., 2018-10-29;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: CAR-T (Differentiation)

D-Mannose Enhanced Immunomodulation of Periodontal Ligament Stem Cells via Inhibiting IL-6 Secretion
Authors: L Guo, Y Hou, L Song, S Zhu, F Lin, Y Bai
Stem Cells Int, 2018-09-09;2018(0):7168231.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human papilloma virus specific immunogenicity and dysfunction of CD8+ T cells in head and neck cancer
Authors: S Krishna, P Ulrich, E Wilson, F Parikh, P Narang, S Yang, AK Read, S Kim-Schulz, JG Park, M Posner, MA Wilson Say, A Sikora, KS Anderson
Cancer Res., 2018-08-28;0(0):.
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

Imperatorin Targets MCL-1 to Sensitize CD133+ Lung Cancer Cells to ??-T Cell-Mediated Cytotoxicity
Authors: C You, Y Yang, B Gao
Cell. Physiol. Biochem., 2018-08-23;49(1):235-244.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells.
Authors: Ghassemi S, Nunez-Cruz S, O'Connor R, Fraietta J, Patel P, Scholler J, Barrett D, Lundh S, Davis M, Bedoya F, Zhang C, Leferovich J, Lacey S, Levine B, Grupp S, June C, Melenhorst J, Milone M
Cancer Immunol Res, 2018-07-20;6(9):1100-1109.
Species: Human
Sample Types: Whole Cells
Applications: CAR-T

Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling
Authors: X Zhao, S Sankaran, J Yap, CT Too, ZZ Ho, G Dolton, M Legut, EC Ren, AK Sewell, A Bertoletti, PA MacAry, J Brzostek, NRJ Gascoigne
Nat Commun, 2018-07-13;9(1):2716.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BET inhibition in advanced cutaneous T cell lymphoma is synergistically potentiated by BCL2 inhibition or HDAC inhibition
Authors: SR Kim, JM Lewis, BM Cyrenne, PF Monico, FN Mirza, KR Carlson, FM Foss, M Girardi
Oncotarget, 2018-06-26;9(49):29193-29207.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer
Authors: M Kim, S Pyo, CH Kang, CO Lee, HK Lee, SU Choi, CH Park
PLoS ONE, 2018-06-06;13(6):e0198347.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option
Authors: H Stamm, F Klingler, EM Grossjohan, J Muschhamme, E Vettorazzi, M Heuser, U Mock, F Thol, G Vohwinkel, E Latuske, C Bokemeyer, R Kischel, C Dos Santos, S Stienen, M Friedrich, M Lutteropp, D Nagorsen, J Wellbrock, W Fiedler
Oncogene, 2018-05-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Site-Specific Gene Editing of Human Hematopoietic Stem Cells for X-Linked Hyper-IgM Syndrome
Authors: CY Kuo, JD Long, B Campo-Fern, S de Oliveir, AR Cooper, Z Romero, MD Hoban, AV Joglekar, GR Lill, ML Kaufman, S Fitz-Gibbo, X Wang, RP Hollis, DB Kohn
Cell Rep, 2018-05-29;23(9):2606-2616.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Histone Modulation Blocks Treg-Induced Foxp3 Binding to the IL-2 Promoter of Virus-Specific CD8? T Cells from Feline Immunodeficiency Virus-Infected Cats
Authors: M Nag, Y Wang, K De Paris, J E Fogle
Viruses, 2018-05-27;10(6):.
Species: Feline
Sample Types: Whole Cells
Applications: Bioassay

Gene Signature-Based Approach Identified MEK1/2 as a Potential Target Associated With Relapse After Anti-TNFα Treatment for Crohn's Disease
Authors: K Gamo, Y Okuzono, M Yabuki, T Ochi, K Sugimura, Y Sato, M Sagara, H Hayashi, Y Ishimura, Y Nishimoto, Y Murakawa, Z Shiokawa, M Gotoh, T Miyazaki, Y Ebisuno
Inflamm. Bowel Dis., 2018-05-18;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3
Authors: A Schmidt, F Marabita, NA Kiani, CC Gross, HJ Johansson, S Éliás, S Rautio, M Eriksson, SJ Fernandes, G Silberberg, U Ullah, U Bhatia, H Lähdesmäki, J Lehtiö, D Gomez-Cabr, H Wiendl, R Lahesmaa, J Tegnér
BMC Biol., 2018-05-07;16(1):47.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women
Authors: C Engdahl, A Bondt, U Harre, J Raufer, R Pfeifle, A Camponesch, M Wuhrer, M Seeling, IL Mårtensson, F Nimmerjahn, G Krönke, HU Scherer, H Forsblad-d, G Schett
Arthritis Res. Ther., 2018-05-02;20(1):84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners
Authors: S Tanaka, C Pfleger, JF Lai, F Roan, SC Sun, SF Ziegler
Cell Rep, 2018-04-17;23(3):796-807.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Characterization of the interaction between human decidua parietalis mesenchymal stem/stromal cells and natural killer cells
Authors: MH Abumaree, E Bahattab, A Alsadoun, A Al Dosaima, FM Abomaray, T Khatlani, B Kalionis, MF El-Muzaini, AO Alawad, AS AlAskar
Stem Cell Res Ther, 2018-04-12;9(1):102.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Multiple Antigen Stimulating Cellular Therapy (MASCT) For Hepatocellular Carcinoma After Curative Treatment: A Retrospective Study
Authors: Y He, Y Guo, J Chen, X Hu, X Li, Y Kong, X Zhang, X Zhou, L Liu, J Hou
J Cancer, 2018-04-06;9(8):1385-1393.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis
Authors: H Pei, L He, M Shao, Z Yang, Y Ran, D Li, Y Zhou, M Tang, T Wang, Y Gong, X Chen, S Yang, M Xiang, L Chen
Sci Rep, 2018-03-27;8(1):5273.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin 35: Inhibitory regulator in monocyte-derived dendritic cell maturation and activation
Authors: X Chen, S Hao, Z Zhao, J Liu, Q Shao, F Wang, D Sun, Y He, W Gao, H Mao
Cytokine, 2018-03-20;108(0):43-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The natural HLA ligandome of glioblastoma stem-like cells: antigen discovery for T cell-based immunotherapy
Authors: MC Neidert, DJ Kowalewski, M Silginer, K Kapolou, L Backert, LK Freudenman, JK Peper, A Marcu, SS Wang, JS Walz, F Wolpert, HG Rammensee, R Henschler, K Lamszus, M Westphal, P Roth, L Regli, S Stevanovi?, M Weller, G Eisele
Acta Neuropathol., 2018-03-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An Isolated TCR ?? Restricted by HLA-A*02:01/CT37 Peptide Redirecting CD8+T Cells To Kill and Secrete IFN-? in Response to Lung Adenocarcinoma Cell Lines
Authors: PO Flores-Vil, M Ganachari, H Guio, JA Mejia, J Granados
J. Immunol., 2018-03-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Molecular transitions in early progenitors during human cord blood hematopoiesis
Authors: S Zheng, E Papalexi, A Butler, W Stephenson, R Satija
Mol. Syst. Biol., 2018-03-15;14(3):e8041.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Non-lytic Lymphocytes Engineered to Express Virus-specific T-cell Receptors Limit HBV Infection by Activating APOBEC3
Authors: S Koh, J Kah, CYL Tham, N Yang, E Ceccarello, A Chia, M Chen, A Khakpoor, A Pavesi, AT Tan, M Dandri, A Bertoletti
Gastroenterology, 2018-03-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glycosyl-phosphatidylinositol-Anchored Anti-HIV Env Single Chain Variable Fragments Interfere with HIV-1 Env Processing and Viral Infectivity
Authors: A Misra, E Gleeson, W Wang, C Ye, P Zhou, JT Kimata
J. Virol., 2018-03-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Early and late changes in natural killer cells in response to ledipasvir/sofosbuvir treatment
Authors: L Golden-Mas, RH McMahan, MS Kriss, AL Kilgore, L Cheng, RJ Dran, A Wieland, HR Rosen
Hepatol Commun, 2018-03-01;2(4):364-375.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Reciprocal Regulation of Glycolysis-Driven Th17 Pathogenicity and Regulatory T Cell Stability by Cdc42
Authors: KW Kalim, JQ Yang, Y Li, Y Meng, Y Zheng, F Guo
J. Immunol., 2018-02-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Efficacy of intracellular immune checkpoint-silenced DC vaccine
Authors: D Wang, XF Huang, B Hong, XT Song, L Hu, M Jiang, B Zhang, H Ning, Y Li, C Xu, X Lou, B Li, Z Yu, J Hu, J Chen, F Yang, H Gao, G Ding, L Liao, L Rollins, L Jones, SY Chen, H Chen
JCI Insight, 2018-02-08;3(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells
Authors: A Seki, S Rutz
J. Exp. Med., 2018-02-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

ILDR2-Fc Is a Novel Regulator of Immune Homeostasis and Inducer of Antigen-Specific Immune Tolerance
Authors: JR Podojil, I Hecht, MY Chiang, I Vaknin, I Barbiro, A Novik, E Neria, G Rotman, SD Miller
J. Immunol., 2018-02-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic CellsviaToll-Like Receptors 2 and 4
Authors: N Ilic, A Gruden-Mov, J Cvetkovic, S Tomic, DB Vucevic, C Aranzamend, M Colic, E Pinelli, L Sofronic-M
Front Immunol, 2018-01-24;9(0):11.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mesenchymal stromal cells of the bone marrow and natural killer cells: cell interactions and cross modulation
Authors: M Najar, M Fayyad-Kaz, N Meuleman, D Bron, H Fayyad-Kaz, L Lagneaux
J Cell Commun Signal, 2018-01-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Similarity and difference in tumor-infiltrating lymphocytes in original tumor tissues and those ofexpanded populations in head and neck cancer
Authors: L Ren, T Matsuda, B Deng, K Kiyotani, T Kato, JH Park, TY Seiwert, EE Vokes, N Agrawal, Y Nakamura
Oncotarget, 2017-12-19;9(3):3805-3814.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Analysis of CTCL cell lines reveals important differences between mycosis fungoides/S�zary syndrome vs. HTLV-1+ leukemic cell lines
Authors: E Netchiporo, J Gantchev, M Tsang, P Thibault, AK Watters, JM Hughes, FM Ghazawi, A Woetmann, N Ødum, D Sasseville, IV Litvinov
Oncotarget, 2017-10-07;8(56):95981-95998.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets
Authors: S Galland, J Vuille, P Martin, I Letovanec, A Caignard, G Fregni, I Stamenkovi
Cell Rep, 2017-09-19;20(12):2891-2905.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of tonsillar IL10 secreting B cells and their role in the pathophysiology of tonsillar hypertrophy
Authors: L Sarmiento, J De Rosa, A Machicote, LA Billordo, P Baz, PM Fernández, I Kaimen Mac, A Blanco, EI Arana
Sci Rep, 2017-09-11;7(1):11077.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity
Authors: Y Nakayama, J Kosek, L Capone, EM Hur, PH Schafer, GE Ringheim
J. Immunol., 2017-08-28;199(7):2388-2407.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells
Authors: VA Gall, AV Philips, N Qiao, K Clise-Dwye, AA Perakis, M Zhang, GT Clifton, P Sukhumalch, Q Ma, SM Reddy, D Yu, JJ Molldrem, GE Peoples, G Alatrash, EA Mittendorf
Cancer Res., 2017-08-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cytomegalovirus infection in HIV-infected and uninfected individuals is characterized by circulating regulatory T cells of unconstrained antigenic specificity
Authors: A Tovar-Sala, A Weinberg
PLoS ONE, 2017-07-06;12(7):e0180691.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T cell activation and differentiation is modulated by a CD6 domain 1 antibody Itolizumab
Authors: U Bughani, A Saha, A Kuriakose, R Nair, RB Sadashivar, R Venkataram, S Patel, AT Deshchougu, SK S, E Montero, HV Pai, DV Palanivelu, R Melarkode, P Nair
PLoS ONE, 2017-07-03;12(7):e0180088.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells
Authors: DL Bolton, K McGinnis, G Finak, P Chattopadh, R Gottardo, M Roederer
PLoS Pathog., 2017-06-27;13(6):e1006445.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Characterization of human FCRL4-positive B cells
Authors: M Jourdan, N Robert, M Cren, C Thibaut, C Duperray, A Kassambara, M Cogné, K Tarte, B Klein, J Moreaux
PLoS ONE, 2017-06-21;12(6):e0179793.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The IGH locus relocalizes to a recombination compartment in the perinucleolar region of differentiating B-lymphocytes
Authors: A Pichugin, OV Iarovaia, A Gavrilov, I Sklyar, N Barinova, A Barinov, E Ivashkin, G Caron, S Aoufouchi, SV Razin, T Fest, M Lipinski, YS Vassetzky
Oncotarget, 2017-06-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
Authors: A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti
JCI Insight, 2017-06-15;2(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Granulocytic myeloid derived suppressor cells from human cord blood modulate T-helper-cell response towards an anti-inflammatory phenotype
Authors: N Köstlin, M Vogelmann, B Spring, J Schwarz, J Feucht, C Härtel, TW Orlikowsky, CF Poets, C Gille
Immunology, 2017-06-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Negative regulation of tumor-infiltrating NK cell in clear cell renal cell carcinoma patients through the exosomal pathway
Authors: Y Xia, Q Zhang, Q Zhen, Y Zhao, N Liu, T Li, Y Hao, Y Zhang, C Luo, X Wu
Oncotarget, 2017-06-06;8(23):37783-37795.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcutaneous immunization with a bandaid prevents experimental otitis media in a polymicrobial model
Authors: LA Novotny, JD Clements, SD Goodman, LO Bakaletz
Clin. Vaccine Immunol., 2017-06-05;0(0):.
Species: Chinchilla
Sample Types: Whole Cells
Applications: Bioassay

Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis
Authors: AP Vicari, AM Schoepfer, B Meresse, L Goffin, O Léger, S Josserand, N Guégan, S Yousefi, A Straumann, N Cerf-Bensu, HU Simon, Y Chvatchko
MAbs, 2017-06-05;0(0):0.
Species: Human
Sample Types: Protein, Whole Cells
Applications: Bioassay, Surface Plasmon Resonance

A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment
Authors: M Mediavilla, J Castro, A Chiappori, D Noyes, DC Hernandez, J Stagg, SJ Antonia
Neoplasia, 2017-06-03;19(7):530-536.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Therapeutic immune monitoring of CD4(+)CD25(+) T cells in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors
Authors: Z Lu, N Xu, X Zhou, G Gao, L Li, J Huang, Y Li, Q Lu, B He, C Pan, X Liu
Oncol Lett, 2017-06-01;14(2):1363-1372.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neonatal myeloid derived suppressor cells show reduced apoptosis and immunosuppressive activity upon infection with Escherichia coli
Authors: A Leiber, J Schwarz, N Köstlin, B Spring, B Fehrenbach, N Katava, CF Poets, C Gille
Eur. J. Immunol., 2017-05-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CCR8(+)FOXp3(+) Treg cells as master drivers of immune regulation
Authors: Y Barsheshet, G Wildbaum, E Levy, A Vitenshtei, C Akinseye, J Griggs, SA Lira, N Karin
Proc. Natl. Acad. Sci. U.S.A., 2017-05-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Intergenic Recombinant HLA-B?46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands
Authors: HG Hilton, CP McMurtrey, AS Han, Z Djaoud, LA Guethlein, JH Blokhuis, JL Pugh, A Goyos, A Horowitz, R Buchli, KW Jackson, W Bardet, DA Bushnell, PJ Robinson, JL Mendoza, ME Birnbaum, M Nielsen, KC Garcia, WH Hildebrand, P Parham
Cell Rep, 2017-05-16;19(7):1394-1405.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-2 prevents deletion of developing T-regulatory cells in the thymus
Authors: DY Hu, RC Wirasinha, CC Goodnow, SR Daley
Cell Death Differ., 2017-05-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Establishment of induced pluripotent stem cells from normal B cells and inducing AID expression in their differentiation into hematopoietic progenitor cells
Authors: F Kawamura, M Inaki, A Katafuchi, Y Abe, N Tsuyama, Y Kurosu, A Yanagi, M Higuchi, S Muto, T Yamaura, H Suzuki, H Noji, S Suzuki, MA Yoshida, M Sasatani, K Kamiya, M Onodera, A Sakai
Sci Rep, 2017-05-10;7(1):1659.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C3d regulates immune checkpoint blockade and enhances antitumor immunity
Authors: JL Platt, I Silva, SJ Balin, AR Lefferts, E Farkash, TM Ross, MC Carroll, M Cascalho
JCI Insight, 2017-05-04;2(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hypoxia favors the generation of human plasma cells
Authors: M Schoenhals, M Jourdan, A Bruyer, A Kassambara, B Klein, J Moreaux
Cell Cycle, 2017-05-02;0(0):1-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ref-1/APE1 as Transcriptional Regulator and Novel Therapeutic Target in Pediatric T-cell Leukemia
Authors: J Ding, ML Fishel, AM Reed, E McAdams, M Czader, AA Cardoso, MR Kelley
Mol. Cancer Ther., 2017-04-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors
Authors: A Van Hout, T D'huys, M Oeyen, D Schols, T Van Loy
PLoS ONE, 2017-04-14;12(4):e0176057.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mechanistic Correlates of Clinical Responses to Omalizumab in the Setting of Oral Immunotherapy for Milk Allergy
Authors: PA Frischmeye, M Masilamani, W Gu, E Brittain, R Wood, J Kim, K Nadeau, KM Jarvinen, A Grishin, R Lindblad, HA Sampson
J. Allergy Clin. Immunol., 2017-04-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-33, IL-25, and TSLP induce a distinct phenotypic and activation profile in human type 2 innate lymphoid cells
Authors: A Camelo, G Rosignoli, Y Ohne, RA Stewart, C Overed-Say, MA Sleeman, RD May
Blood Adv, 2017-03-30;1(10):577-589.
Species: Human
Sample Types: Whole Cells

EBV induces persistent NF-?B activation and contributes to survival of EBV-positive neoplastic T- or NK-cells
Authors: H Takada, KI Imadome, H Shibayama, M Yoshimori, L Wang, Y Saitoh, S Uota, S Yamaoka, T Koyama, N Shimizu, K Yamamoto, S Fujiwara, O Miura, A Arai
PLoS ONE, 2017-03-27;12(3):e0174136.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses
Authors: S Tousa, M Semitekolo, I Morianos, A Banos, AI Trochoutso, TM Brodie, N Poulos, K Samitas, M Kapasa, D Konstantop, G Paraskevop, M Gaga, CM Hawrylowic, F Sallusto, G Xanthou
Proc. Natl. Acad. Sci. U.S.A, 2017-03-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin 2 and interleukin 10 function synergistically to promote CD8(+) T cell cytotoxicity, which is suppressed by regulatory T cells in breast cancer
Authors: X Li, P Lu, B Li, W Zhang, R Yang, Y Chu, K Luo
Int. J. Biochem. Cell Biol, 2017-03-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Selection of single chain antibody fragments binding to the extracellular domain of 4-1BB receptor by phage display technology
Authors: S Bagheri, M Yousefi, E Safaie Qam, F Riazi-Rad, M Abolhassan, V Younesi, R Dorostkar, AA Movassaghp, Z Sharifzade
Tumour Biol, 2017-03-01;39(3):1010428317695.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SUN2 silencing impairs CD4 T cell proliferation and alters sensitivity to HIV-1 infection independently of Cyclophilin A
Authors: DA Donahue, F Porrot, N Couespel, O Schwartz
J. Virol, 2017-02-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

??TCR immunoglobulin constant region domain exchange in human ??TCRs improves TCR pairing without altering TCR gene-modified T cell function
Authors: C Tao, H Shao, W Zhang, H Bo, F Wu, H Shen, S Huang
Mol Med Rep, 2017-02-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates
Authors: MM Shikhagaie, ÅK Björklund, J Mjösberg, JS Erjefält, AS Cornelisse, XR Ros, SM Bal, JJ Koning, RE Mebius, M Mori, M Bruchard, B Blom, H Spits
Cell Rep, 2017-02-14;18(7):1761-1773.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PKC? links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton
Authors: GJ Britton, R Ambler, DJ Clark, EV Hill, HM Tunbridge, KE McNally, BR Burton, P Butterweck, C Sabatos-Pe, LA Hampton-O', P Verkade, C Wlfing, DC Wraith
Elife, 2017-01-31;6(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1
Authors: JE Hammonds, N Beeman, L Ding, S Takushi, AC Francis, JJ Wang, GB Melikyan, P Spearman
PLoS Pathog, 2017-01-27;13(1):e1006181.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A sestrin-dependent Erk-Jnk-p38 MAPK activation complex inhibits immunity during aging
Authors: A Lanna, DC Gomes, B Muller-Dur, T McDonnell, D Escors, DW Gilroy, JH Lee, M Karin, AN Akbar
Nat. Immunol, 2017-01-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy
Authors: R Havunen, M Siurala, S Sorsa, S Grönberg-V, M Behr, S Tähtinen, JM Santos, P Karell, J Rusanen, DM Nettelbeck, A Ehrhardt, A Kanerva, A Hemminki
Mol Ther Oncolytics, 2016-12-31;4(0):77-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TGF-beta Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner.
Authors: Elias S, Schmidt A, Kannan V, Andersson J, Tegner J
Front Immunol, 2016-12-23;7(0):603.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity
Authors: Ivan Carcamo-Or
Cell Stem Cell, 2016-12-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications
Authors: L J Spicer
Domest. Anim. Endocrinol, 2016-12-11;59(0):90-99.
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay

Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages
Sci Rep, 2016-12-09;6(0):38597.
Species: Bat - Pteropus alecto
Sample Types: Whole Cells
Applications: Bioassay

Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency
Proc. Natl. Acad. Sci. U.S.A, 2016-12-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML
Mol Ther Methods Clin Dev, 2016-12-07;3(0):16074.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Glycosylphosphatidylinositol-Anchored Variable Region of Llama Heavy Chain-Only Antibody JM4 Efficiently Blocks both Cell-Free and T Cell-T Cell Transmission of Human Immunodeficiency Virus Type 1
Authors: L Liu, W Wang, J Matz, C Ye, L Bracq, J Delon, JT Kimata, Z Chen, S Benichou, P Zhou
J. Virol., 2016-11-14;90(23):10642-10659.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of screen-printed tryptophan-kynurenine immunosensor for in vitro assay of kynurenine-mediated immunosuppression effect of cancer cells on activated T-cells
Authors: Yadollah Omidi
Biosens Bioelectron, 2016-11-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Native cellulose nanofibrills induce immune tolerance in vitro by acting on dendritic cells
Sci Rep, 2016-08-25;6(0):31618.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells
Authors: Fabrizio Antonangel
Oncoimmunology, 2016-08-05;5(10):e1218105.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice
Authors: M Ke, H Wang, Y Zhou, J Li, Y Liu, M Zhang, J Dou, T Xi, B Shen, C Zhou
Oncotarget, 2016-08-02;7(31):49509-49526.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Circ Res, 2016-07-14;0(0):.
Species: Human
Sample Types: Plasma
Applications: Bioassay

Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
Authors: Jun Li
Nat Commun, 2016-06-13;7(0):11730.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effects of Cigarette Smoke Condensate on Oxidative Stress, Apoptotic Cell Death, and HIV Replication in Human Monocytic Cells
PLoS ONE, 2016-05-20;11(5):e0155791.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human macrophages induce CD4(+)Foxp3(+) regulatory T cells via binding and re-release of TGF-beta.
Authors: Schmidt A, Zhang X, Joshi R, Iqbal S, Wahlund C, Gabrielsson S, Harris R, Tegner J
Immunol Cell Biol, 2016-05-10;94(8):747-62.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation
Nat Commun, 2016-05-05;7(0):11473.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional differences in hepatitis C virus nonstructural (NS) 3/4A- and 5A-specific T cell responses
Sci Rep, 2016-05-04;6(0):24991.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of engineered T cells expressing a chimeric CD16-CD3? receptor to improve the clinical efficacy of mogamulizumab therapy against adult T cell leukemia
Authors: H Tanaka, H Fujiwara, F Ochi, K Tanimoto, N Casey, S Okamoto, J Mineno, K Kuzushima, H Shiku, T Sugiyama, J Barrett, M Yasukawa
Clin Cancer Res, 2016-04-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes
Authors: RB Jones, S Mueller, R O'Connor, K Rimpel, DD Sloan, D Karel, HC Wong, EK Jeng, AS Thomas, JB Whitney, SY Lim, C Kovacs, E Benko, S Karandish, SH Huang, MJ Buzon, M Lichterfel, A Irrinki, JP Murry, A Tsai, H Yu, R Geleziunas, A Trocha, MA Ostrowski, Irvi
PLoS Pathog, 2016-04-15;12(4):e1005545.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate.
Authors: Schmidt A, Eriksson M, Shang M, Weyd H, Tegner J
PLoS ONE, 2016-02-17;11(2):e0148474.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1
Authors: TM Garcia-Bat, E Kim, F Concha-Ben, S Trivedi, RB Mailliard, A Gambotto, RL Ferris
J. Immunol, 2016-02-05;196(6):2870-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies.
Authors: Rodgers D, Mazagova M, Hampton E, Cao Y, Ramadoss N, Hardy I, Schulman A, Du J, Wang F, Singer O, Ma J, Nunez V, Shen J, Woods A, Wright T, Schultz P, Kim C, Young T
Proc Natl Acad Sci U S A, 2016-01-12;113(4):E459-68.
Species: Human
Sample Types: Whole Cells
Applications: CAR-T (Bioassay)

Association of CD147 and Calcium Exporter PMCA4 Uncouples IL-2 Expression from Early TCR Signaling.
Authors: Supper V, Schiller H, Paster W, Forster F, Boulegue C, Mitulovic G, Leksa V, Ohradanova-Repic A, Machacek C, Schatzlmaier P, Zlabinger G, Stockinger H
J Immunol, 2016-01-04;196(3):1387-99.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA (Standard)

Granulocytic Myeloid-Derived Suppressor Cells Accumulate in Human Placenta and Polarize toward a Th2 Phenotype.
Authors: Kostlin N, Hofstadter K, Ostermeir A, Spring B, Leiber A, Haen S, Abele H, Bauer P, Pollheimer J, Hartl D, Poets C, Gille C
J Immunol, 2015-12-28;196(3):1132-45.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of Four-Jointed Box 1 (FJX1)-Specific Peptides for Immunotherapy of Nasopharyngeal Carcinoma.
Authors: Chai S, Yap Y, Foo Y, Yap L, Ponniah S, Teo S, Cheong S, Patel V, Lim K
PLoS ONE, 2015-11-04;10(11):e0130464.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Impaired survival of regulatory T cells in pulmonary sarcoidosis.
Authors: Broos C, van Nimwegen M, KleinJan A, ten Berge B, Muskens F, in 't Veen J, Annema J, Lambrecht B, Hoogsteden H, Hendriks R, Kool M, van den Blink B
Respir Res, 2015-09-16;16(0):108.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alpha-Particle-Induced Complex Chromosome Exchanges Transmitted through Extra-Thymic Lymphopoiesis In Vitro Show Evidence of Emerging Genomic Instability.
Authors: Sumption N, Goodhead D, Anderson R
PLoS ONE, 2015-08-07;10(8):e0134046.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-CD20 Therapy Acts via FcgammaRIIIA to Diminish Responsiveness of Human Natural Killer Cells.
Authors: Capuano C, Romanelli M, Pighi C, Cimino G, Rago A, Molfetta R, Paolini R, Santoni A, Galandrini R
Cancer Res, 2015-07-30;75(19):4097-108.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Antileukemia multifunctionality of CD4(+) T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer.
Authors: Fujiwara H, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M
Leukemia, 2015-06-24;29(12):2393-401.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation.
Authors: Ahn Y, Weeres M, Neulen M, Choi J, Kang S, Heo D, Bergerson R, Blazar B, Miller J, Verneris M
Eur J Immunol, 2015-06-22;45(8):2335-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Increased CD160 expression on circulating natural killer cells in atherogenesis.
Authors: Zuo J, Shan Z, Zhou L, Yu J, Liu X, Gao Y
J Transl Med, 2015-06-13;13(0):188.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.
Authors: Zingoni A, Cecere F, Vulpis E, Fionda C, Molfetta R, Soriani A, Petrucci M, Ricciardi M, Fuerst D, Amendola M, Mytilineos J, Cerboni C, Paolini R, Cippitelli M, Santoni A
J Immunol, 2015-06-12;195(2):736-48.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells.
Authors: Odorizzi P, Pauken K, Paley M, Sharpe A, Wherry E
J Exp Med, 2015-06-01;212(7):1125-37.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Human Monoclonal Antibody against Hepatitis B Surface Antigen with Potent Neutralizing Activity.
Authors: Cerino A, Bremer C, Glebe D, Mondelli M
PLoS ONE, 2015-04-29;10(4):e0125704.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis.
Authors: Ling Y, Cypowyj S, Aytekin C, Galicchio M, Camcioglu Y, Nepesov S, Ikinciogullari A, Dogu F, Belkadi A, Levy R, Migaud M, Boisson B, Bolze A, Itan Y, Goudin N, Cottineau J, Picard C, Abel L, Bustamante J, Casanova J, Puel A
J Exp Med, 2015-04-27;212(5):619-31.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hair regrowth in alopecia areata patients following Stem Cell Educator therapy.
Authors: Li Y, Yan B, Wang H, Li H, Li Q, Zhao D, Chen Y, Zhang Y, Li W, Zhang J, Wang S, Shen J, Li Y, Guindi E, Zhao Y
BMC Med, 2015-04-20;13(0):87.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain.
Authors: Yan J, Hao C, DeLucia M, Swanson S, Florens L, Washburn M, Ahn J, Skowronski J
J Biol Chem, 2015-04-06;290(21):13279-92.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The upregulation of LAG-3 on T cells defines a subpopulation with functional exhaustion and correlates with disease progression in HIV-infected subjects.
Authors: Tian X, Zhang A, Qiu C, Wang W, Yang Y, Qiu C, Liu A, Zhu L, Yuan S, Hu H, Wang W, Wei Q, Zhang X, Xu J
J Immunol, 2015-03-16;194(8):3873-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein.
Authors: Pery E, Sheehy A, Nebane N, Brazier A, Misra V, Rajendran K, Buhrlage S, Mankowski M, Rasmussen L, White E, Ptak R, Gabuzda D
J Biol Chem, 2015-02-27;290(16):10504-17.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
Authors: James B Canavan
Gut, 2015-02-24;65(4):584-94.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter.
Authors: Hill E, Ng T, Burton B, Oakley C, Malik K, Wraith D
Eur J Immunol, 2015-02-17;45(4):1103-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.
Authors: Fischer N, Elson G, Magistrelli G, Dheilly E, Fouque N, Laurendon A, Gueneau F, Ravn U, Depoisier J, Moine V, Raimondi S, Malinge P, Di Grazia L, Rousseau F, Poitevin Y, Calloud S, Cayatte P, Alcoz M, Pontini G, Fagete S, Broyer L, Corbier M, Schrag D, Didelot G, Bosson N, Costes N, Cons L, Buatois V, Johnson Z, Ferlin W, Masternak K, Kosco-Vilbois M
Nat Commun, 2015-02-12;6(0):6113.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Bioassay

Inhibition of G-protein betagamma signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cells.
Authors: Yost E, Hynes T, Hartle C, Ott B, Berlot C
PLoS ONE, 2015-01-28;10(1):e0116575.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines.
Authors: Chien W, Le Beux C, Rachinel N, Julien M, Lacroix C, Allas S, Sahakian P, Cornut-Thibaut A, Lionnard L, Kucharczak J, Aouacheria A, Abribat T, Salles G
Sci Rep, 2015-01-28;5(0):8068.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4.
Authors: Ranzani, Valeria, Rossetti, Grazisa, Panzeri, Ilaria, Arrigoni, Alberto, Bonnal, Raoul J, Curti, Serena, Gruarin, Paola, Provasi, Elena, Sugliano, Elisa, Marconi, Maurizio, De Francesco, Raffaele, Geginat, Jens, Bodega, Beatrice, Abrignani, Sergio, Pagani, Massimil
Nat Immunol, 2015-01-26;16(3):318-25.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In vivo maintenance of human regulatory T cells during CD25 blockade.
Authors: Huss, David J, Mehta, Devangi, Sharma, Akanksha, You, Xiaojun, Riester, Katherin, Sheridan, James P, Amaravadi, Lakshmi, Elkins, Jacob S, Fontenot, Jason D
J Immunol, 2015-01-01;194(1):84-92.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tricyclic covalent inhibitors selectively target Jak3 through an active site thiol.
Authors: Goedken E, Argiriadi M, Banach D, Fiamengo B, Foley S, Frank K, George J, Harris C, Hobson A, Ihle D, Marcotte D, Merta P, Michalak M, Murdock S, Tomlinson M, Voss J
J Biol Chem, 2014-12-31;290(8):4573-89.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Role and species-specific expression of colon T cell homing receptor GPR15 in colitis.
Authors: Nguyen L, Pan J, Dinh T, Hadeiba H, O'Hara E, Ebtikar A, Hertweck A, Gokmen M, Lord G, Jenner R, Butcher E, Habtezion A
Nat Immunol, 2014-12-22;16(2):207-13.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection.
Authors: Li H, Richert-Spuhler L, Evans T, Gillis J, Connole M, Estes J, Keele B, Klatt N, Reeves R
PLoS Pathog, 2014-12-11;10(12):e1004551.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.
Authors: Hoffmann F, Kuhn P, Laurent S, Hauck S, Berer K, Wendlinger S, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister H, Alexander T, Hiepe F, Kumpfel T, Crawford H, Wekerle H, Hohlfeld R, Lichtenthaler S, Meinl E
J Immunol, 2014-12-10;194(2):542-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-146a controls Th1-cell differentiation of human CD4+ T lymphocytes by targeting PRKCepsilon.
Authors: Mohnle P, Schutz S, van der Heide V, Hubner M, Luchting B, Sedlbauer J, Limbeck E, Hinske L, Briegel J, Kreth S
Eur J Immunol, 2014-11-27;45(1):260-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
Authors: Lam, Sharon, Sung, Julia, Cruz, Conrad, Castillo-Caro, Paul, Ngo, Minhtran, Garrido, Carolina, Kuruc, Joann, Archin, Nancie, Rooney, Cliona, Margolis, David, Bollard, Catherin
Mol Ther, 2014-11-04;23(2):387-95.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ctla-4 modulates the differentiation of inducible Foxp3+ Treg cells but IL-10 mediates their function in experimental autoimmune encephalomyelitis.
Authors: Verhagen J, Gabrysova L, Shepard E, Wraith D
PLoS ONE, 2014-09-19;9(9):e108023.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction.
Authors: Kurktschiev P, Raziorrouh B, Schraut W, Backmund M, Wachtler M, Wendtner C, Bengsch B, Thimme R, Denk G, Zachoval R, Dick A, Spannagl M, Haas J, Diepolder H, Jung M, Gruener N
J Exp Med, 2014-09-15;211(10):2047-59.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells.
Authors: Lanna, Alessio, Henson, Sian M, Escors, David, Akbar, Arne N
Nat Immunol, 2014-08-24;15(10):965-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mapping the HLA ligandome landscape of acute myeloid leukemia: a targeted approach toward peptide-based immunotherapy.
Authors: Berlin C, Kowalewski D, Schuster H, Mirza N, Walz S, Handel M, Schmid-Horch B, Salih H, Kanz L, Rammensee H, Stevanovic S, Stickel J
Leukemia, 2014-08-05;29(3):647-59.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A p38 MAPK-mediated alteration of COX-2/PGE2 regulates immunomodulatory properties in human mesenchymal stem cell aging.
Authors: Yu K, Lee J, Kim H, Hong I, Choi S, Seo Y, Kang I, Kim J, Lee B, Lee S, Kurtz A, Seo K, Kang K
PLoS ONE, 2014-08-04;9(8):e102426.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling.
Authors: Wu L, Wang C, Boisson B, Misra S, Rayman P, Finke J, Puel A, Casanova J, Li X
J Immunol, 2014-07-14;193(4):1590-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The regulation and role of c-FLIP in human Th cell differentiation.
Authors: Kylaniemi M, Kaukonen R, Myllyviita J, Rasool O, Lahesmaa R
PLoS ONE, 2014-07-14;9(7):e102022.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells.
Authors: Shipony, Zohar, Mukamel, Zohar, Cohen, Netta Me, Landan, Gilad, Chomsky, Elad, Zeliger, Shlomit, Fried, Yael Cha, Ainbinder, Elena, Friedman, Nir, Tanay, Amos
Nature, 2014-07-13;513(7516):115-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance.
Authors: Martinelli R, Zeiger A, Whitfield M, Sciuto T, Dvorak A, Van Vliet K, Greenwood J, Carman C
J Cell Sci, 2014-07-07;127(0):3720-34.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Granulocytic myeloid derived suppressor cells expand in human pregnancy and modulate T-cell responses.
Authors: Kostlin N, Kugel H, Spring B, Leiber A, Marme A, Henes M, Rieber N, Hartl D, Poets C, Gille C
Eur J Immunol, 2014-07-07;44(9):2582-91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tetherin can restrict cell-free and cell-cell transmission of HIV from primary macrophages to T cells.
Authors: Giese, Sebastia, Marsh, Mark
PLoS Pathog, 2014-07-03;10(7):e1004189.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cytokine conditioning enhances systemic delivery and therapy of an oncolytic virus.
Authors: Ilett E, Kottke T, Donnelly O, Thompson J, Willmon C, Diaz R, Zaidi S, Coffey M, Selby P, Harrington K, Pandha H, Melcher A, Vile R
Mol Ther, 2014-06-24;22(10):1851-63.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.
Authors: Molfetta R, Quatrini L, Capuano C, Gasparrini F, Zitti B, Zingoni A, Galandrini R, Santoni A, Paolini R
Eur J Immunol, 2014-06-17;44(9):2761-70.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A novel self-lipid antigen targets human T cells against CD1c(+) leukemias.
Authors: Lepore M, de Lalla C, Gundimeda S, Gsellinger H, Consonni M, Garavaglia C, Sansano S, Piccolo F, Scelfo A, Haussinger D, Montagna D, Locatelli F, Bonini C, Bondanza A, Forcina A, Li Z, Ni G, Ciceri F, Jeno P, Xia C, Mori L, Dellabona P, Casorati G, De Libero G
J Exp Med, 2014-06-16;211(7):1363-77.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

High mobility group nucleosomal binding domain 2 (HMGN2) SUMOylation by the SUMO E3 ligase PIAS1 decreases the binding affinity to nucleosome core particles.
Authors: Wu J, Kim S, Kwak M, Jeong J, Min H, Yoon H, Ahn J, Shin J
J Biol Chem, 2014-05-28;289(29):20000-11.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-2 phosphorylates STAT5 to drive IFN-gamma production and activation of human dendritic cells.
Authors: Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, Velge-Roussel F, Baron C, Lebranchu Y
J Immunol, 2014-05-14;192(12):5660-70.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.
Authors: Kofler D, Marson A, Dominguez-Villar M, Xiao S, Kuchroo V, Hafler D
J Clin Invest, 2014-05-08;124(6):2513-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells.
Authors: Kim, Dae Won, Zloza, Andrew, Broucek, Joseph, Schenkel, Jason M, Ruby, Carl, Samaha, Georges, Kaufman, Howard L
J Transl Med, 2014-05-06;12(0):113.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human AdV-specific T cells: persisting in vitro functionality despite lethal irradiation.
Authors: Geyeregger R, Freimuller C, Stemberger J, Fischer G, Witt V, Fritsch G
Bone Marrow Transplant, 2014-04-28;49(7):934-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice.
Authors: Tong Q, He S, Xie F, Mochizuki K, Liu Y, Mochizuki I, Meng L, Sun H, Zhang Y, Guo Y, Hexner E, Zhang Y
J Immunol, 2014-04-23;192(11):5012-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

E2F1 renders prostate cancer cell resistant to ICAM-1 mediated antitumor immunity by NF-kappaB modulation.
Authors: Ren Z, Kang W, Wang L, Sun B, Ma J, Zheng C, Sun J, Tian Z, Yang X, Xiao W
Mol Cancer, 2014-04-17;13(0):84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia.
Authors: Rebhandl S, Huemer M, Zaborsky N, Gassner F, Catakovic K, Felder T, Greil R, Geisberger R
Eur J Immunol, 2014-04-15;44(7):2175-87.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epstein-Barr virus infection induces indoleamine 2,3-dioxygenase expression in human monocyte-derived macrophages through p38/mitogen-activated protein kinase and NF-kappaB pathways: impairment in T cell functions.
Authors: Liu W, Lin Y, Xiao H, Xing S, Chen H, Chi P, Zhang G
J Virol, 2014-04-02;88(12):6660-71.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor-activated TCRgammadelta(+) T cells from gastric cancer patients induce the antitumor immune response of TCRalphabeta(+) T cells via their antigen-presenting cell-like effects.
Authors: Mao C, Mou X, Zhou Y, Yuan G, Xu C, Liu H, Zheng T, Tong J, Wang S, Chen D
J Immunol Res, 2014-03-31;2014(0):593562.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The secretion of IL-6 by CpG-ODN-treated cancer cells promotes T-cell immune responses partly through the TLR-9/AP-1 pathway in oral squamous cell carcinoma.
Authors: Ruan M, Thorn K, Liu S, Li S, Yang W, Zhang C, Zhang C
Int J Oncol, 2014-03-21;44(6):2103-10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Reversal of tumor immune inhibition using a chimeric cytokine receptor.
Authors: Leen A, Sukumaran S, Watanabe N, Mohammed S, Keirnan J, Yanagisawa R, Anurathapan U, Rendon D, Heslop H, Rooney C, Brenner M, Vera J
Mol Ther, 2014-03-20;22(6):1211-20.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Signal tranducers and activators of transcription: expression and function in anti-neutrophil cytoplasmic antibody-associated vasculitis.
Authors: Wilde B, Hoerning A, Kribben A, Witzke O, Dolff S
Mol Med Rep, 2014-03-20;9(6):2316-20.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential IL-10 production by DCs determines the distinct adjuvant effects of LPS and PTX in EAE induction.
Authors: Zhou H, Wang Y, Lian Q, Yang B, Ma Y, Wu X, Sun S, Liu Y, Sun B
Eur J Immunol, 2014-03-07;44(5):1352-62.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells.
Authors: Kurachi M, Barnitz R, Yosef N, Odorizzi P, DiIorio M, Lemieux M, Yates K, Godec J, Klatt M, Regev A, Wherry E, Haining W
Nat Immunol, 2014-03-02;15(4):373-83.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Building and optimizing a virus-specific T cell receptor library for targeted immunotherapy in viral infections.
Authors: Banu, Nasirah, Chia, Adeline, Ho, Zi Zong, Garcia, Alfonso, Paravasivam, Komathi, Grotenbreg, Gijsbert, Bertoletti, Antonio, Gehring, Adam J
Sci Rep, 2014-02-25;4(0):4166.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Linking the circadian rhythm gene Arntl2 to interleukin 21 expression in type 1 diabetes.
Authors: Lebailly B, He C, Rogner U
Diabetes, 2014-02-11;63(6):2148-57.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Anti-beta(2)M monoclonal antibodies kill myeloma cells via cell- and complement-mediated cytotoxicity.
Authors: Zhang M, Qian J, Lan Y, Lu Y, Li H, Hong B, Zheng Y, He J, Yang J, Yi Q
Int J Cancer, 2014-02-07;135(5):1132-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse.
Authors: Choudhuri K, Llodra J, Roth E, Tsai J, Gordo S, Wucherpfennig K, Kam L, Stokes D, Dustin M
Nature, 2014-02-02;507(7490):118-23.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Absence of a role for interleukin-13 in inflammatory bowel disease.
Authors: Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, Hoque S, Ghanbari A, Joe-Njoku I, Giuffrida P, Rovedatti L, Geginat J, Corazza G, MacDonald T
Eur J Immunol, 2014-02-01;44(2):370-85.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gemcitabine sensitizes lung cancer cells to Fas/FasL system-mediated killing.
Authors: Siena L, Pace E, Ferraro M, Di Sano C, Melis M, Profita M, Spatafora M, Gjomarkaj M
Immunology, 2014-02-01;141(2):242-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection.
Authors: Boswell K, Paris R, Boritz E, Ambrozak D, Yamamoto T, Darko S, Wloka K, Wheatley A, Narpala S, McDermott A, Roederer M, Haubrich R, Connors M, Ake J, Douek D, Kim J, Petrovas C, Koup R
PLoS Pathog, 2014-01-30;10(1):e1003853.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Extracorporeal photopheresis increases neutrophilic myeloid-derived suppressor cells in patients with GvHD.
Authors: Rieber N, Wecker I, Neri D, Fuchs K, Schafer I, Brand A, Pfeiffer M, Lang P, Bethge W, Amon O, Handgretinger R, Hartl D
Bone Marrow Transplant, 2014-01-27;49(4):545-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A spliced antigenic peptide comprising a single spliced amino acid is produced in the proteasome by reverse splicing of a longer peptide fragment followed by trimming.
Authors: Michaux A, Larrieu P, Stroobant V, Fonteneau J, Jotereau F, Van den Eynde B, Moreau-Aubry A, Vigneron N
J Immunol, 2014-01-22;192(4):1962-71.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function in inflamed tissues.
Authors: Honda T, Egen J, Lammermann T, Kastenmuller W, Torabi-Parizi P, Germain R
Immunity, 2014-01-16;40(2):235-47.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Multiplexed screening of natural humoral immunity identifies antibodies at fine specificity for complex and dynamic viral targets.
Authors: McCutcheon, Krista M, Gray, Julia, Chen, Natalie, Liu, Keyi, Park, Minha, Ellsworth, Stote, Tripp, Ralph A, Tompkins, S Mark, Johnson, Scott K, Samet, Shelly, Pereira, Lenore, Kauvar, Lawrence
MAbs, 2014-01-08;6(2):460-73.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses.
Authors: Ashino S, Takeda K, Li H, Taylor V, Joetham A, Pine P, Gelfand E
J Allergy Clin Immunol, 2013-12-22;133(4):1162-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18.
Authors: Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H
PLoS ONE, 2013-12-20;8(12):e82586.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hepatitis C virus impairs natural killer cell-mediated augmentation of complement synthesis.
Authors: Kim H, Bose S, Meyer K, Ray R
J Virol, 2013-12-18;88(5):2564-71.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes.
Authors: Kumari S, Walchli S, Fallang L, Yang W, Lund-Johansen F, Schumacher T, Olweus J
Proc Natl Acad Sci U S A, 2013-12-16;111(1):403-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neutrophil microparticles modulate cytokine production by natural killer cells.
Authors: Pliyev B, Kalintseva M, Abdulaeva S, Yarygin K, Savchenko V
Cytokine, 2013-12-16;65(2):126-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An investigation into IgE-facilitated allergen recognition and presentation by human dendritic cells.
Authors: Sharquie I, Al-Ghouleh A, Fitton P, Clark M, Armour K, Sewell H, Shakib F, Ghaemmaghami A
BMC Immunol, 2013-12-13;14(0):54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton.
Authors: Forster F, Paster W, Supper V, Schatzlmaier P, Sunzenauer S, Ostler N, Saliba A, Eckerstorfer P, Britzen-Laurent N, Schutz G, Schmid J, Zlabinger G, Naschberger E, Sturzl M, Stockinger H
J Immunol, 2013-12-13;192(2):771-81.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA (Standard)

Highly pathological influenza A virus infection is associated with augmented expression of PD-1 by functionally compromised virus-specific CD8+ T cells.
Authors: Rutigliano, John A, Sharma, Shalini, Morris, Melissa, Oguin, Thomas H, McClaren, Jennifer, Doherty, Peter C, Thomas, Paul G
J Virol, 2013-11-20;88(3):1636-51.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mature cytotoxic CD56(bright)/CD16(+) natural killer cells can infiltrate lymph nodes adjacent to metastatic melanoma.
Cancer Res, 2013-11-13;74(0):81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.
Authors: Boisson B, Wang C, Pedergnana V, Wu L, Cypowyj S, Rybojad M, Belkadi A, Picard C, Abel L, Fieschi C, Puel A, Li X, Casanova J
Immunity, 2013-10-10;39(4):676-86.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon gamma-induced intratumoral expression of CXCL9 alters the local distribution of T cells following immunotherapy with
Authors: Guirnalda P, Wood L, Goenka R, Crespo J, Paterson Y
Oncoimmunology, 2013-07-23;2(8):e25752.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization.
Authors: Hawkins R, Larjo A, Tripathi S, Wagner U, Luu Y, Lonnberg T, Raghav S, Lee L, Lund R, Ren B, Lahdesmaki H, Lahesmaa R
Immunity, 2013-06-20;38(6):1271-84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulatory T cell phenotype and function 4 years after GAD-alum treatment in children with type 1 diabetes.
Authors: Pihl M, Akerman L, Axelsson S, Cheramy M, Hjorth M, Mallone R, Ludvigsson J, Casas R
Clin Exp Immunol, 2013-06-01;172(3):394-402.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-22-producing CD4+ cells are depleted in actively inflamed colitis tissue.
Authors: Leung J, Davenport M, Wolff M, Wiens K, Abidi W, Poles M, Cho I, Ullman T, Mayer L, Loke P
Mucosal Immunol, 2013-05-22;7(1):124-33.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells.
Authors: Cai, Minchao, Wu, Jing, Mao, Chaoming, Ren, Jianmin, Li, Pu, Li, Xiao, Zhong, Jiuchang, Xu, Chundi, Zhou, Tong
J Transl Med, 2013-04-29;11(0):103.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia.
Authors: Davila M, Kloss C, Gunset G, Sadelain M
PLoS ONE, 2013-04-09;8(4):e61338.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Detection of TCD4+ subsets in human carotid atheroma.
Authors: Oliveira R, Silva R, Teo F, Mineiro M, Ferreira M, Altemani A, Mamoni R, Menezes F, Blotta M
Cytokine, 2013-03-07;62(1):131-40.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.
Authors: Knosp C, Schiering C, Spence S, Carroll H, Nel H, Osbourn M, Jackson R, Lyubomska O, Malissen B, Ingram R, Fitzgerald D, Powrie F, Fallon P, Johnston J, Kissenpfennig A
J Immunol, 2013-03-01;190(7):3235-45.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients.
Authors: Srivastava R, Lee S, Andrade Filho P, Lord C, Jie H, Davidson H, Lopez-Albaitero A, Gibson S, Gooding W, Ferrone S, Ferris R
Clin Cancer Res, 2013-02-26;19(7):1858-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H-Y antigen-binding B cells develop in male recipients of female hematopoietic cells and associate with chronic graft vs. host disease.
Authors: Sahaf B, Yang Y, Arai S, Herzenberg L, Herzenberg L, Miklos D
Proc Natl Acad Sci U S A, 2013-02-04;110(8):3005-10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Study of the quantitative, functional, cytogenetic, and immunoregulatory properties of bone marrow mesenchymal stem cells in patients with B-cell chronic lymphocytic leukemia.
Authors: Pontikoglou C, Kastrinaki M, Klaus M, Kalpadakis C, Katonis P, Alpantaki K, Pangalis G, Papadaki H
Stem Cells Dev, 2013-02-01;22(9):1329-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma.
Authors: Bonanno G, Mariotti A, Procoli A, Folgiero V, Natale D, De Rosa L, Majolino I, Novarese L, Rocci A, Gambella M, Ciciarello M, Scambia G, Palumbo A, Locatelli F, De Cristofaro R, Rutella S
J Transl Med, 2012-12-11;10(0):247.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients.
Authors: Brusic, Ana, Hainz, Ursula, Wadleigh, Martha, Neuberg, Donna, Su, Mei, Canning, Christin, Deangelo, Daniel J, Stone, Richard, Lee, Jeng-Shi, Mulligan, Richard, Ritz, Jerome, Dranoff, Glenn, Sasada, Tetsuro, Wu, Catherin
Oncoimmunology, 2012-10-01;1(7):1095-1103.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma.
Authors: Huse K, Bakkebo M, Walchli S, Oksvold M, Hilden V, Forfang L, Bredahl M, Liestol K, Alizadeh A, Smeland E, Myklebust J
PLoS ONE, 2012-10-01;7(10):e46117.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor Microenvironment Macrophage Inhibitory Factor Directs the Accumulation of Interleukin-17-producing Tumor-infiltrating Lymphocytes and Predicts Favorable Survival in Nasopharyngeal Carcinoma Patients.
Authors: Li J, Mo H, Xiong G, Zhang L, He J, Huang Z, Liu Z, Chen Q, Du Z, Zheng L, Qian C, Zeng Y
J Biol Chem, 2012-08-14;287(42):35484-95.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.
Authors: Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC
Nature, 2012-03-25;484(7395):529-33.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Antigen-independent induction of Tim-3 expression on human T cells by the common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway.
Authors: Mujib S, Jones RB, Lo C, Aidarus N, Clayton K, Sakhdari A, Benko E, Kovacs C, Ostrowski MA
J. Immunol., 2012-03-14;188(8):3745-56.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of myeloid derived suppressor cells in dogs with naturally occurring cancer.
Authors: Goulart MR, Pluhar GE, Ohlfest JR
PLoS ONE, 2012-03-13;7(3):e33274.
Species: Canine
Sample Types: Whole Cells
Applications: Bioassay

Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite.
Authors: Emara M, Royer PJ, Mahdavi J
J. Biol. Chem., 2011-12-28;287(8):5756-63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Semen clusterin is a novel DC-SIGN ligand.
Authors: Sabatte J, Faigle W, Ceballos A, Morelle W, Rodrígues CR, Lenicov FR, Thepaut M, Fieschi F, Malchiodi E, Fernandez M, Arenzana-Seisdedos F, Lortat-Jacob H, Michalski JC, Geffner J, Amigorena S
J. Immunol., 2011-10-17;187(10):5299-309.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis.
Authors: Hogan AE, Tobin AM, Ahern T, Corrigan MA, Gaoatswe G, Jackson R, O'Reilly V, Lynch L, Doherty DG, Moynagh PN, Kirby B, O'Connell J, O'Shea D
Diabetologia, 2011-07-09;54(11):2745-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Protein kinase C and NF-kappaB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection.
Authors: Raposo RA, Trudgian DC, Thomas B, van Wilgenburg B, Cowley SA, James W
J. Immunol., 2011-06-10;187(2):748-59.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans.
Authors: Di Meglio P, Di Cesare A, Laggner U
PLoS ONE, 2011-02-22;6(2):e17160.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis.
Authors: Bowness P, Ridley A, Shaw J
J. Immunol., 2011-01-19;186(0):2672.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma.
Authors: Buglio D, Khaskhely NM, Voo KS, Martinez-Valdez H, Liu YJ, Younes A
Blood, 2011-01-14;117(10):2910-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mouse natural killer (NK) cells express the nerve growth factor receptor TrkA, which is dynamically regulated.
Authors: Ralainirina N, Brons NH, Ammerlaan W, Hoffmann C, Hentges F, Zimmer J
PLoS ONE, 2010-12-01;5(12):e15053.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma.
Authors: Ungerer C, Doberstein K, Burger C, Hardt K, Boehncke WH, Bohm B, Pfeilschifter J, Dummer R, Mihic-Probst D, Gutwein P
Biochem. Biophys. Res. Commun., 2010-09-17;401(3):363-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of functional human NK cells in an immunodeficient mouse model with the ability to provide protection against tumor challenge.
Authors: Kwant-Mitchell A, Pek EA, Rosenthal KL
PLoS ONE, 2009-12-21;4(12):e8379.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells.
Authors: Maarof G, Bouchet-Delbos L, Gary-Gouy H, Durand-Gasselin I, Krzysiek R, Dalloul A
Blood, 2009-11-24;115(9):1718-26.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients.
Authors: Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, Kwok SK, Ju JH, Park KS, Cho SG, Park SH, Kim HY, Min JK
Immunol. Lett., 2009-11-04;127(2):150-6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms.
Authors: Correale J, Farez M
J. Immunol., 2009-10-07;183(9):5999-6012.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines.
Authors: Witte K, Gruetz G, Volk HD, Looman AC, Asadullah K, Sterry W, Sabat R, Wolk K
Genes Immun., 2009-10-01;10(8):702-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma.
Authors: Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, Carbone A, Colombatti A, Pinto A, Aldinucci D
Int. J. Cancer, 2009-09-01;125(5):1092-101.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses.
Authors: Duraisingham SS, Hornig J, Gotch F, Patterson S
J. Immunol., 2009-07-22;183(4):2242-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients.
Authors: Pfistershammer K, Lawitschka A, Klauser C, Leitner J, Weigl R, Heemskerk MH, Pickl WF, Majdic O, Bohmig GA, Fischer GF, Greinix HT, Steinberger P
Blood, 2009-07-17;114(11):2323-32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Autologous melanoma vaccine induces antitumor and self-reactive immune responses that affect patient survival and depend on MHC class II expression on vaccine cells.
Authors: Lotem M, Machlenkin A, Hamburger T, Nissan A, Kadouri L, Frankenburg S, Gimmon Z, Elias O, David IB, Kuznetz A, Shiloni E, Peretz T
Clin. Cancer Res., 2009-07-14;15(15):4968-77.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
Clin. Immunol., 2009-06-25;133(1):27-44.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells.
Authors: Lundqvist A, Yokoyama H, Smith A, Berg M, Childs R
Blood, 2009-02-06;113(24):6120-7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells.
Authors: Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H
Clin. Exp. Immunol., 2008-11-26;155(2):266-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Local IL-21 promotes the therapeutic activity of effector T cells by decreasing regulatory T cells within the tumor microenvironment.
Authors: Kim-Schulze S, Kim HS, Fan Q, Kim DW, Kaufman HL
Mol. Ther., 2008-11-25;17(2):380-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities.
Authors: Rickel EA, Siegel LA, Yoon BR, Rottman JB, Kugler DG, Swart DA, Anders PM, Tocker JE, Comeau MR, Budelsky AL
J. Immunol., 2008-09-15;181(6):4299-310.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Helminth infections associated with multiple sclerosis induce regulatory B cells.
Authors: Correale J, Farez M, Razzitte G
Ann. Neurol., 2008-08-01;64(2):187-99.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes.
Authors: Pene J, Chevalier S, Preisser L, Venereau E, Guilleux MH, Ghannam S, Moles JP, Danger Y, Ravon E, Lesaux S, Yssel H, Gascan H
J. Immunol., 2008-06-01;180(0):7423.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients.
Authors: Zheng CF, Jones GJ, Shi M, Wiseman JC, Marr KJ, Berenger BM, Huston SM, Gill MJ, Krensky AM, Kubes P, Mody CH
J. Immunol., 2008-06-01;180(11):7221-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-15 does not affect IEL development in the thymus but regulates homeostasis of putative precursors and mature CD8 alpha alpha+ IELs in the intestine.
Authors: Lai YG, Hou MS, Hsu YW, Chang CL, Liou YH, Tsai MH, Lee F, Liao NS
J. Immunol., 2008-03-15;180(6):3757-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD27 defines phenotypically and functionally different human NK cell subsets.
Authors: Vossen MT, Matmati M, Hertoghs KM, Baars PA, Gent MR, Leclercq G, Hamann J, Kuijpers TW, van Lier RA
J. Immunol., 2008-03-15;180(6):3739-45.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of an in vitro potency bioassay for therapeutic IL-13 antagonists: the A-549 cell bioassay.
Authors: Miller R, Sadhukhan R, Wu C
J. Immunol. Methods, 2008-03-07;334(1):134-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
Authors: Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB
AIDS Res. Hum. Retroviruses, 2008-03-01;24(3):453-62.
Applications: ELISA (Standard)

Isolation and characterization of CD8+ regulatory T cells in multiple sclerosis.
Authors: Correale J, Villa A
J. Neuroimmunol., 2008-01-30;195(1):121-34.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients.
Authors: Christophi GP, Hudson CA, Gruber RC, Christophi CP, Mihai C, Mejico LJ, Jubelt B, Massa PT
Lab. Invest., 2008-01-21;88(3):243-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
Authors: Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle ES, Hyde DM, Wu LC, Hymowitz SG, Martin F
J. Clin. Invest., 2007-12-01;117(12):3868-3878.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of in vitro antimurine thymocyte globulin-induced regulatory T cells that inhibit graft-versus-host disease in vivo.
Authors: Ruzek MC, Waire JS, Hopkins D, Lacorcia G, Sullivan J, Roberts BL, Richards SM, Nahill SR, Williams JM, Scaria A, Dzuris J, Shankara S, Garman RD
Blood, 2007-11-19;111(3):1726-34.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation.
Authors: Schade AE, Schieven GL, Townsend R, Jankowska AM, Susulic V, Zhang R, Szpurka H, Maciejewski JP
Blood, 2007-10-25;111(3):1366-77.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis.
Authors: Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C
J. Leukoc. Biol., 2007-07-05;82(4):946-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.
Authors: Conrad C, Boyman O, Tonel G, Tun-Kyi A, Laggner U, de Fougerolles A, Kotelianski V, Gardner H, Nestle FO
Nat. Med., 2007-07-01;13(7):836-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death.
Authors: Toscano MA, Bianco GA, Ilarregui JM, Croci DO, Correale J, Hernandez JD, Zwirner NW, Poirier F, Riley EM, Baum LG, Rabinovich GA
Nat. Immunol., 2007-06-24;8(8):825-34.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

A synergistic antitumor effect of interleukin-2 addition with CD80 immunogene therapy for peritoneal metastasis of gastric carcinoma.
Authors: Kosaka K, Yashiro M, Sakate Y, Hirakawa K
Dig. Dis. Sci., 2007-04-03;52(8):1946-53.
Species: Human, Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells.
Authors: Bayry J, Triebel F, Kaveri SV, Tough DF
J. Immunol., 2007-04-01;178(7):4184-93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.
Authors: Bulanova E, Budagian V, Duitman E, Orinska Z, Krause H, Ruckert R, Reiling N, Bulfone-Paus S
J. Biol. Chem., 2007-02-27;282(18):13167-79.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

GATA3 up-regulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells.
Authors: De Fanis U, Mori F, Kurnat RJ, Lee WK, Bova M, Adkinson NF, Casolaro V
Blood, 2007-01-18;109(10):4343-50.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).
Authors: de la Fuente MA, Sasahara Y, Calamito M, Anton IM, Elkhal A, Gallego MD, Suresh K, Siminovitch K, Ochs HD, Anderson KC, Rosen FS, Geha RS, Ramesh N
Proc. Natl. Acad. Sci. U.S.A., 2007-01-09;104(3):926-31.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells.
Authors: Gleissner CA, Zastrow A, Klingenberg R, Kluger MS, Konstandin M, Celik S, Haemmerling S, Shankar V, Giese T, Katus HA, Dengler TJ
Eur. J. Immunol., 2007-01-01;37(1):177-92.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
Authors: Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P
AIDS, 2007;21(10):1263-72.
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)

An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
J. Exp. Med., 2006-11-20;203(12):2763-77.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors.
Authors: Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS
J. Immunol., 2006-10-01;177(7):4488-94.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
Authors: Ebert EC, Mehta V
Cell. Immunol., 2006-08-17;241(1):7-13.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dendritic cells can turn CD4+ T lymphocytes into vascular endothelial growth factor-carrying cells by intercellular neuropilin-1 transfer.
Authors: Bourbie-Vaudaine S, Blanchard N, Hivroz C, Romeo PH
J. Immunol., 2006-08-01;177(3):1460-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function.
Authors: Roda-Navarro P, Vales-Gomez M, Chisholm SE, Reyburn HT
Proc. Natl. Acad. Sci. U.S.A., 2006-07-18;103(30):11258-63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD16+ monocyte-derived macrophages activate resting T cells for HIV infection by producing CCR3 and CCR4 ligands.
Authors: Ancuta P, Autissier P, Wurcel A, Zaman T, Stone D, Gabuzda D
J. Immunol., 2006-05-15;176(10):5760-71.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Th2 cytokine response in Major Depressive Disorder patients before treatment.
Authors: Kiryushko D, Pavon L, Novitskaya V, Sandoval-Lopez G, Soroka V, Eugenia Hernandez M, Klingelhofer J, Loria F, Lukanidin E, Estrada I, Berezin V, Perez M, Bock E, Moreno J, Avila U, Leff P, Anton B, Heinze G
J. Neuroimmunol., 2006-02-02;172(1):156-65.
Applications: ELISA (Standard)

Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
Authors: Hanabuchi S, Watanabe N, Wang YH, Ito T, Shaw J, Cao W, Qin FX, Liu YJ
Blood, 2006-01-05;107(9):3617-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo.
Authors: von Strandmann EP, Hansen HP, Reiners KS, Schnell R, Borchmann P, Merkert S, Simhadri VR, Draube A, Reiser M, Purr I, Hallek M, Engert A
Blood, 2005-10-06;107(5):1955-62.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Resistance to myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis by death receptor 6-deficient mice.
Authors: Schmidt CS, Zhao J, Chain J, Hepburn D, Gitter B, Sandusky G, Chintalacharuvu S, Glasebrook A, Na S
J. Immunol., 2005-08-15;175(4):2286-92.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.
Authors: Dulos J, van der Vleuten MA, Kavelaars A, Heijnen CJ, Boots AM
Arthritis Rheum., 2005-03-01;52(3):770-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism.
Authors: Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, Kufe D
J. Immunol., 2005-02-15;174(4):2376-86.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Involvement of Fc gamma RI (CD64) in the mechanism of HIV-1 inhibition by polyclonal IgG purified from infected patients in cultured monocyte-derived macrophages.
Authors: Holl V, Hemmerter S, Burrer R, Schmidt S, Bohbot A, Aubertin AM, Moog C
J. Immunol., 2004-11-15;173(10):6274-83.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
J. Immunol., 2004-09-01;173(5):3482-91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
Authors: Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
Biochem. J., 2004-06-01;380(0):425-33.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
Authors: Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA
J. Immunol., 2004-05-01;172(9):5213-21.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells.
Authors: Megjugorac NJ, Young HA, Amrute SB, Olshalsky SL, Fitzgerald-Bocarsly P
J. Leukoc. Biol., 2004-01-23;75(3):504-14.
Species: Human
Sample Types:
Applications: Bioassay

BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone.
Authors: Moreaux J, Legouffe E, Jourdan E, Quittet P, Reme T, Lugagne C, Moine P, Rossi JF, Klein B, Tarte K
Blood, 2003-12-04;103(8):3148-57.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cutting edge: immune cells as sources and targets of the IL-10 family members?
Authors: Wolk K, Kunz S, Asadullah K, Sabat R
J. Immunol., 2002-06-01;168(11):5397-402.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
Authors: Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW
J. Immunol., 2002-06-01;168(11):5699-708.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
Authors: Oppmann, B, Lesley, R, Blom, B, Timans, J C, Xu, Y, Hunte, B, Vega, F, Yu, N, Wang, J, Singh, K, Zonin, F, Vaisberg, E, Churakova, T, Liu, M, Gorman, D, Wagner, J, Zurawski, S, Liu, Y, Abrams, J S, Moore, K W, Rennick, D, de Waal-Malefyt, R, Hannum, C, Bazan, J F, Kastelein, R A
Immunity, 2000-11-01;13(5):715-25.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Repeated exposure induces periportal fibrosis in Schistosoma mansoni-infected baboons: role of TGF-beta and IL-4.
Authors: Farah IO, Mola PW, Kariuki TM, Nyindo M, Blanton RE, King CL
J. Immunol., 2000-05-15;164(10):5337-43.
Applications: ELISA (Standard)

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells.
Authors: Nestle, F O, Alijagic, S, Gilliet, M, Sun, Y, Grabbe, S, Dummer, R, Burg, G, Schadendorf, D
Nat Med, 1998-03-01;4(3):328-32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay