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Rat IgG1 Isotype Control

Catalog #: MAB005
83 Citations 1 Review Datasheet
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MAB005
Detection of Rat IgG Isotype Control by Flow Cytometry
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Product Details
Citations (83)
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Supplemental Products
Reviews (1)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Rat IgG1 Isotype Control Summary

Specificity
Selected for use as rat IgG1 isotype control. In direct ELISAs, no cross-react with recombinant human (rh) 6Ckine, recombinant mouse (rm) 6Ckine, rhACT II (rhMIP-1 beta ), rhBLC/BCA-1, rmC10, recombinant rat (rr) CINC-1, rrCINC-2 alpha, rrCINC-2 beta, rmCRG-2, rhENA-78, rhEotaxin, rmEotaxin, rhEotaxin 2, rhFractalkine, rmFractalkine, rhGCP-2, rmGCP-2, rhGRO alpha, rhGRO beta, rhGRO gamma, rhHCC-1, rhHCC-4, rhI-309, rhIL-8, rhIL-16, rhIP-10, rmJE, rmKC, rmLymphotactin, rmMARC, rhMCP-1, rhMCP-1 R, rhMCP-2, rhMCP-3, rhMCP-4, rmMCP-5, rhMDC, rmMDC, rhMIG, rmMIG, rhMIP-1 alpha, rmMIP-1 alpha, rmMIP-1 beta, rmMIP-1 gamma, rhMIP-1δ, rmMIP-2, rhMIP-3 alpha, rrMIP-3 alpha, rhMIP-3 beta, rmMIP-3 beta, recombinant viral (rv) MIP-I, rvMIP-II, rvMIP-III, rhMPIF-1, rhNAP-2, rhParc, rhRANTES, rmRANTES, rhSDF-1 alpha, rmSDF-1 alpha, rhSDF-1 beta, rhTarc, rmTCA-3, rhTeck, or rmTeck.
Source
Monoclonal Rat IgG1 Clone # 43414
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
KLH
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Control
Negative control for use in conjunction with R&D Systems antibodies. Use at the same concentration as the detection antibody.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Control Detection of Rat IgG Isotype Control by Flow Cytometry View Larger

Detection of Rat IgG Control by Flow Cytometry Mouse platelets were stained with Rat Anti-Mouse GPVI Monoclonal Antibody (Catalog # MAB6758, filled histogram) or Rat IgG Isotype Control Antibody (Catalog # MAB005, open histogram), followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog F0113).

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IgG1

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

Long Name
Immunoglobulin G1
Alternate Names
IgG1; Igh-4; RGD1359539; VH7183

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Citations for Rat IgG1 Isotype Control

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

83 Citations: Showing 1 - 10
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  1. Targeting WDxR motif reprograms immune microenvironment and inhibits hepatocellular carcinoma progression
    Authors: H Zhang, G Chen, X Feng, H Song, L Meng, Y Fu, J Yang, Z Fan, Y Ding, Z Du, J Wang, L Yang, J Zhang, L Sun, Z Liu, Z Zhang, Q Li, X Fan
    Embo Molecular Medicine, 2023-03-22;0(0):e15924.
  2. Granulocyte colony-stimulating factor mediates bone loss via the activation of IL-1?/JNK signaling pathway in murine Staphylococcus aureus-induced osteomyelitis
    Authors: Song, M;Deng, M;Peng, Z;Dai, F;Wang, Y;Shu, W;Zhou, X;Zhang, J;Hou, Y;Yu, B;
    International immunopharmacology
    Species: Mouse
    Sample Types: In Vivo
    Applications: In vivo assay
  3. Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading
    Authors: Yadav, P;Ortega, JG;Tamaki, W;Chien, C;Chang, KC;Biswas, N;Pan, S;Nilsson, J;Yin, X;Bhattacharyya, A;Boostanpour, K;Jujaray, T;Wang, J;Tsukui, T;Sheppard, D;Li, B;Maishan, M;Taenaka, H;Matthay, MA;Muramatsu, R;Maliskova, L;Ghosh, A;Eckalbar, WL;Molofsky, AB;Wolters, PJ;Tamaki, SJ;Bivona, T;Abate, AR;Wagner, A;Tharp, KM;Bhattacharya, M;
    bioRxiv : the preprint server for biology
    Species: Mouse, Transgenic Mouse
    Sample Types: In Vivo
    Applications: Neutralization Control
  4. Stress systems exacerbate the inflammatory response after corneal abrasion in sleep-deprived mice via the IL-17 signaling pathway
    Authors: Xue, Y;Xu, P;Hu, Y;Liu, S;Yan, R;Liu, S;Li, Y;Liu, J;Fu, T;Li, Z;
    Mucosal immunology
    Species: Mouse
    Sample Types: In Vivo
    Applications: In vivo assay
  5. IL-3 orchestrates ulcerative colitis pathogenesis by controlling the development and the recruitment of splenic reservoir neutrophils
    Authors: Bénard, A;Mittelstädt, A;Klösch, B;Glanz, K;Müller, J;Schoen, J;Nüse, B;Brunner, M;Naschberger, E;Stürzl, M;Mattner, J;Muñoz, LE;Sohn, K;Grützmann, R;Weber, GF;
    Cell reports
    Species: Mouse
    Sample Types:
    Applications: In Vivo
  6. The fetal response to maternal inflammation is dependent upon maternal IL-6 in a murine model
    Authors: Bermick, J;Watson, S;Lueschow, S;McElroy, SJ;
    Cytokine
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  7. Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses
    Authors: T Hirz, S Mei, H Sarkar, Y Kfoury, S Wu, BM Verhoeven, AO Subtelny, DV Zlatev, MW Wszolek, K Salari, E Murray, F Chen, EZ Macosko, CL Wu, DT Scadden, DM Dahl, N Baryawno, PJ Saylor, PV Kharchenko, DB Sykes
    Nature Communications, 2023-02-07;14(1):663.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo Control
  8. Hepatic PTP4A1 ameliorates high-fat diet-induced hepatosteatosis and hyperglycemia by the activation of the CREBH/FGF21 axis
    Authors: Byungtae Hwang, Min-Gi Kwon, Min Ji Cho, Nam-Kyung Lee, Jangwook Lee, Jeong Woong Lee et al.
    Theranostics
  9. CCL3 in the bone marrow microenvironment causes bone loss and bone marrow adiposity in aged mice
    Authors: Degang Yu, Shuhong Zhang, Chao Ma, Sen Huang, Long Xu, Jun Liang et al.
    JCI Insight
  10. Leukotriene B4 Receptor 2 Mediates the Production of G-CSF That Plays a Critical Role in Steroid-Resistant Neutrophilic Airway Inflammation
    Authors: DW Kwak, D Park, JH Kim
    Biomedicines, 2022-11-19;10(11):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  11. Crosstalk between TBK1/IKK epsilon and the type I interferon pathway contributes to tubulointerstitial inflammation and kidney tubular injury
    Authors: Gina Córdoba-David, Jorge García-Giménez, Regiane Cardoso Castelo-Branco, Susana Carrasco, Pablo Cannata, Alberto Ortiz et al.
    Frontiers in Pharmacology
  12. Single-cell transcriptomics reveals a senescence-associated IL-6/CCR6 axis driving radiodermatitis
    Authors: M Paldor, O Levkovitch, D Eidelshtei, R Adar, CD Enk, Y Marmary, S Elgavish, Y Nevo, H Benyamini, I Plaschkes, S Klein, A Mali, S Rose-John, A Peled, E Galun, JH Axelrod
    Oncogene, 2022-07-04;0(0):e15653.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo Control
  13. Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement
    Authors: H Kamei, T Ishii, Y Nishii
    Oncogene, 2022-06-02;12(1):9243.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization Control
  14. Chemokine CCL9 Is Upregulated Early in Chronic Kidney Disease and Counteracts Kidney Inflammation and Fibrosis
    Authors: C Hemmers, C Schulte, J Wollenhaup, DWL Wong, E Harlacher, S Orth-Alamp, BM Klinkhamme, SH Schirmer, M Böhm, N Marx, T Speer, P Boor, J Jankowski, H Noels
    Biomedicines, 2022-02-10;10(2):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Isotype Control
  15. Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses
    Authors: M Bruchard, M Geindreau, A Perrichet, C Truntzer, E Ballot, R Boidot, C Racoeur, E Barsac, F Chalmin, C Hibos, T Baranek, C Paget, B Ryffel, C Rébé, C Paul, F Végran, F Ghiringhel
    Nature Immunology, 2022-01-31;23(2):262-274.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo Control
  16. Irradiated fibroblasts increase interleukin-6 expression and induce migration of head and neck squamous cell carcinoma
    Authors: S Suzuki, S Toyoma, Y Kawasaki, T Yamada
    PLoS ONE, 2022-01-28;17(1):e0262549.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization Control
  17. Granulocyte colony-stimulating factor (G-CSF) mediates bone resorption in periodontitis
    Authors: H Yu, T Zhang, H Lu, Q Ma, D Zhao, J Sun, Z Wang
    BMC Oral Health, 2021-06-12;21(1):299.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  18. ADAM17 Boosts Cholesterol Efflux and Downstream Effects of High-Density Lipoprotein on Inflammatory Pathways in Macrophages
    Authors: Vishal Kothari, Jingjing Tang, Yi He, Farah Kramer, Jenny E. Kanter, Karin E. Bornfeldt
    Arteriosclerosis, Thrombosis, and Vascular Biology
  19. Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells
    Authors: Mingcan Yu, Subhashis Pal, Cameron W. Paterson, Jau-Yi Li, Abdul Malik Tyagi, Jonathan Adams et al.
    Journal of Clinical Investigation
  20. Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice
    Authors: RJP Brown, B Tegtmeyer, J Sheldon, T Khera, Anggakusum, D Todt, G Vieyres, R Weller, S Joecks, Y Zhang, S Sake, D Bankwitz, K Welsch, C Ginkel, M Engelmann, G Gerold, E Steinmann, Q Yuan, M Ott, FWR Vondran, T Krey, LJ Ströh, C Miskey, Z Ivics, V Herder, W Baumgärtne, C Lauber, M Seifert, AW Tarr, CP McClure, G Randall, Y Baktash, A Ploss, VLD Thi, E Michailidi, M Saeed, L Verhoye, P Meuleman, N Goedecke, D Wirth, CM Rice, T Pietschman
    Sci Adv, 2020-11-04;6(45):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  21. p38&alpha in Macrophages Aggravates Arterial Endothelium Injury by Releasing IL-6 through phosphorylating Megakaryocytic Leukemia 1
    Authors: M Zhang, J Gao, X Zhao, M Zhao, D Ma, X Zhang, D Tian, B Pan, X Yan, J Wu, X Meng, H Yin, L Zheng
    Redox Biology, 2020-11-01;38(0):101775.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  22. The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation
    Authors: Chunliang Xu, Sung Kyun Lee, Dachuan Zhang, Paul S. Frenette
    Immunity
  23. Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration
    Authors: K Mulfaul, E Ozaki, N Fernando, K Brennan, KR Chirco, E Connolly, C Greene, A Maminishki, RG Salomon, M Linetsky, R Natoli, RF Mullins, M Campbell, SL Doyle
    Cell Rep, 2020-02-18;30(7):2209-2224.e5.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization Control
  24. PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells
    Authors: M Yu, A Malik Tyag, JY Li, J Adams, TL Denning, MN Weitzmann, RM Jones, R Pacifici
    Nat Commun, 2020-01-24;11(1):468.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  25. Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis
    Authors: Y Takagaki, SM Lee, Z Dongqing, M Kitada, K Kanasaki, D Koya
    Autophagy, 2020-01-22;0(0):1-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  26. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells
    Authors: P Wang, X Qi, G Xu, J Liu, J Guo, X Li, X Ma, H Sun
    Aging (Albany NY), 2019-09-26;11(18):7402-7415.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  27. CCL20-CCR6 axis modulated traumatic brain injury-induced visual pathologies
    Authors: M Das, X Tang, JY Han, K Mayilsamy, E Foran, MR Biswal, R Tzekov, SS Mohapatra, S Mohapatra
    J Neuroinflammation, 2019-05-31;16(1):115.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Isotype Control
  28. Protein tyrosine phosphatase non-receptor type 22 modulates colitis in a microbiota-dependent manner
    Authors: MR Spalinger, TS Schmidt, M Schwarzfis, L Hering, K Atrott, S Lang, C Gottier, A Geirnaert, C Lacroix, X Dai, DJ Rawlings, AC Chan, C von Mering, G Rogler, M Scharl
    J. Clin. Invest., 2019-05-20;130(0):2527-2541.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  29. Trauma Induces Emergency Hematopoiesis through IL-1/MyD88 dependent production of G-CSF1
    Authors: Anja Fuchs, Darlene A. Monlish, Sarbani Ghosh, Shin-Wen Chang, Grant V. Bochicchio, Laura G. Schuettpelz et al.
    The Journal of Immunology
  30. Deficiency of Socs3 leads to brain-targeted experimental autoimmune encephalomyelitis via enhanced neutrophil activation and ROS production
    Authors: Zhaoqi Yan, Wei Yang, Luke Parkitny, Sara A. Gibson, Kevin S. Lee, Forrest Collins et al.
    JCI Insight
  31. Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC
    Authors: B John, C Naczki, C Patel, A Ghoneum, S Qasem, Z Salih, N Said
    Oncogene, 2019-02-14;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Isotype Control
  32. IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma.
    Authors: Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada, Youngkyu Park et al.
    Cancer Discovery
  33. Anti-PD1 ‘SHR-1210ʹ aberrantly targets pro-angiogenic receptors and this polyspecificity can be ablated by paratope refinement
    Authors: William J.J. Finlay, James E. Coleman, Jonathan S. Edwards, Kevin S. Johnson
    mAbs
  34. IL10 restrains autoreactive B cells in transgenic mice expressing inactive RAG1
    Authors: Victoria L. Palmer, Alexandra N. Worth, Robyn L. Scott, Greg A. Perry, Mei Yan, Quan-Zhen Li et al.
    Cellular Immunology
  35. Modulating bone marrow hematopoietic lineage potential to prevent bone metastasis in breast cancer
    Authors: JM Ubellacker, N Baryawno, N Severe, MJ DeCristo, J Sceneay, JN Hutchinson, MT Haider, CS Rhee, Y Qin, WM Gregory, AC Garrido-Ca, I Holen, JE Brown, RE Coleman, DT Scadden, SS McAllister
    Cancer Res., 2018-07-31;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  36. A Role for Hypocretin/Orexin in Metabolic and Sleep Abnormalities in a Mouse Model of Non-metastatic Breast Cancer
    Authors: Jeremy C. Borniger, William H. Walker II, Surbhi, Kathryn M. Emmer, Ning Zhang, Abigail A. Zalenski et al.
    Cell Metabolism
  37. Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin
    Authors: BL Hoh, K Rojas, L Lin, HZ Fazal, S Hourani, KW Nowicki, MB Schneider, K Hosaka
    J Am Heart Assoc, 2018-04-13;7(8):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  38. Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models
    Authors: Y Mita, K Nakayama, S Inari, Y Nishito, Y Yoshioka, N Sakai, K Sotani, T Nagamura, Y Kuzuhara, K Inagaki, M Iwasaki, H Misu, M Ikegawa, T Takamura, N Noguchi, Y Saito
    Nat Commun, 2017-11-21;8(1):1658.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo Control
  39. Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut-microbiota-brain axis
    Authors: JC Zhang, W Yao, C Dong, C Yang, Q Ren, M Ma, K Hashimoto
    Transl Psychiatry, 2017-05-30;7(5):e1138.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Isotype Control
  40. Granulocyte colony-stimulating factor blockade enables dexamethasone to inhibit lipopolysaccharide-induced murine lung neutrophils
    Authors: J Banuelos, Y Cao, SC Shin, BS Bochner, P Avila, S Li, X Jiang, MW Lingen, RP Schleimer, NZ Lu
    PLoS ONE, 2017-05-19;12(5):e0177884.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  41. Cooperation of Gastric Mononuclear Phagocytes with Helicobacter pylori during Colonization
    Authors: M Viladomiu, J Bassaganya, N Tubau-Juni, B Kronsteine, A Leber, CW Philipson, V Zoccoli-Ro, R Hontecilla
    J. Immunol, 2017-03-06;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  42. Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway
    Authors: SN Schock, NV Chandra, Y Sun, T Irie, Y Kitagawa, B Gotoh, L Coscoy, A Winoto
    Cell Death Differ, 2017-01-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney
    Authors: Ulf Panzer
    Immunity, 2016-11-15;45(5):1078-1092.
    Species: Mouse
    Sample Types:
    Applications: Neutralization
  44. Presentation of Cryptic Peptides by MHC Class I Is Enhanced by Inflammatory Stimuli
    J Immunol, 2016-09-19;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  45. IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer
    Authors: MS Caetano, H Zhang, AM Cumpian, L Gong, N Unver, EJ Ostrin, S Daliri, SH Chang, CE Ochoa, S Hanash, C Behrens, II Wistuba, C Sternberg, H Kadara, CG Ferreira, SS Watowich, SJ Moghaddam
    Cancer Res., 2016-04-01;76(11):3189-99.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  46. Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury.
    Authors: Bohannon J, Luan L, Hernandez A, Afzal A, Guo Y, Patil N, Fensterheim B, Sherwood E
    J Leukoc Biol, 2015-11-04;99(4):629-40.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  47. Anti-G-CSF treatment induces protective tumor immunity in mouse colon cancer by promoting protective NK cell, macrophage and T cell responses
    Authors: Katherine T. Morris, Eliseo F. Castillo, Anita L. Ray, Lea L. Weston, Robert A. Nofchissey, Joshua A. Hanson et al.
    Oncotarget
  48. Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages.
    Authors: Sotoodehnejadnematalahi F, Staples K, Chrysanthou E, Pearson H, Ziegler-Heitbrock L, Burke B
    PLoS ONE, 2015-06-09;10(6):e0125799.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  49. G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation.
    Authors: Agarwal S, Lakoma A, Chen Z, Hicks J, Metelitsa L, Kim E, Shohet J
    Cancer Res, 2015-04-23;75(12):2566-79.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  50. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
    Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
    J Immunol, 2015-04-17;194(11):5407-16.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization Control
  51. Coordinate expansion of murine hematopoietic and mesenchymal stem cell compartments by SHIPi.
    Authors: Brooks R, Iyer S, Akada H, Neelam S, Russo C, Chisholm J, Kerr W
    Stem Cells, 2015-03-01;33(3):848-58.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization Control
  52. Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration.
    Authors: Levy O, Calippe B, Lavalette S, Hu S, Raoul W, Dominguez E, Housset M, Paques M, Sahel J, Bemelmans A, Combadiere C, Guillonneau X, Sennlaub F
    EMBO Mol Med, 2015-02-01;7(2):211-26.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells, Whole Organism
    Applications: In Vivo, Neutralization
  53. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
    Authors: Chandler, Ronald L, Damrauer, Jeffrey, Raab, Jesse R, Schisler, Jonathan, Wilkerson, Matthew, Didion, John P, Starmer, Joshua, Serber, Daniel, Yee, Della, Xiong, Jessie, Darr, David B, Pardo-Manuel de Villena, Fernando, Kim, William, Magnuson, Terry
    Nat Commun, 2015-01-27;6(0):6118.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization Control
  54. Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation.
    Authors: McKelvey R, Berta T, Old E, Ji R, Fitzgerald M
    J Neurosci, 2015-01-14;35(2):457-66.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  55. Upregulation of Bone Morphogenetic Protein-1/Mammalian Tolloid and Procollagen C-Proteinase Enhancer-1 in Corneal Scarring
    Authors: Francois Malecaze, Dawiyat Massoudi, Pierre Fournie, Cyrielle Tricoire, Myriam Cassagne, Marilyne Malbouyres et al.
    Investigative Ophthalmology & Visual Science
  56. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
    Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M
    Nature, 2014-10-22;515(7525):130-3.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  57. Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
    Authors: Kowalewska P, Patrick A, Fox-Robichaud A
    PLoS ONE, 2014-09-03;9(9):e104537.
    Species: Mouse
    Sample Types: In Vivo
    Applications: IHC-Fr
  58. Delayed Neutralization of Interleukin 6 Reduces Organ Injury, Selectively Suppresses Inflammatory Mediator, and Partially Normalizes Immune Dysfunction Following Trauma and Hemorrhagic Shock
    Authors: Yong Zhang, Jinxiang Zhang, Sebastian Korff, Faez Ayoob, Yoram Vodovotz, Timothy R. Billiar
    Shock
  59. Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells
    Authors: Ana J. Chucair-Elliott, Christopher Conrady, Min Zheng, Chandra M. Kroll, Thomas E. Lane, Daniel J. J. Carr
    Glia
  60. Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas.
    Authors: Picco G, Beatson R, Taylor-Papadimitriou J, Burchell J
    Eur J Immunol, 2014-04-17;44(7):1947-55.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  61. Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitis.
    Authors: Klein M, Brouwer M, Angele B, Geldhoff M, Marquez G, Varona R, Hacker G, Schmetzer H, Hacker H, Hammerschmidt S, van der Ende A, Pfister H, van de Beek D, Koedel U
    PLoS ONE, 2014-04-03;9(4):e93057.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  62. The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck.
    Authors: Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, Wang B, Vivi A, Tassini M, Van Rooijen N, Pozzi G, Ricci S, Andrew P, Koedel U, Moxon E, Oggioni M
    PLoS Pathog, 2014-03-20;10(3):e1004026.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  63. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
    Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
    Nat Med, 2014-03-02;20(4):377-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  64. G-CSF drives a posttraumatic immune program that protects the host from infection.
    Authors: Gardner J, Noel J, Nikolaidis N, Karns R, Aronow B, Ogle C, McCormack F
    J Immunol, 2014-01-27;192(5):2405-17.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  65. Retinoic acid prevents mesenteric lymph node dendritic cells from inducing IL-13-producing inflammatory Th2 cells.
    Authors: Yokota-Nakatsuma A, Takeuchi H, Ohoka Y, Kato C, Song S, Hoshino T, Yagita H, Ohteki T, Iwata M
    Mucosal Immunol, 2013-11-13;7(4):786-801.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Isotype Control
  66. Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-alpha antibodies.
    Authors: Bhargava R, Altmann C, Andres-Hernando A, Webb R, Okamura K, Yang Y, Falk S, Schmidt E, Faubel S
    PLoS ONE, 2013-11-12;8(11):e79037.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Isotype Control
  67. Microarray analyses demonstrate the involvement of type I interferons in psoriasiform pathology development in D6-deficient mice.
    Authors: Baldwin H, Pallas K, King V, Jamieson T, McKimmie C, Nibbs R, Carballido J, Jaritz M, Rot A, Graham G
    J Biol Chem, 2013-11-05;288(51):36473-83.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  68. Catecholamine stress alters neutrophil trafficking and impairs wound healing by beta2-adrenergic receptor-mediated upregulation of IL-6.
    Authors: Kim M, Gorouhi F, Ramirez S, Granick J, Byrne B, Soulika A, Simon S, Isseroff R
    J Invest Dermatol, 2013-10-11;134(3):809-17.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  69. Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure.
    Authors: Kulkarni, Shilpa, Singh, Pankaj K, Ghosh, Sanchita, Posarac, Ana, Singh, Vijay K
    Cytokine, 2013-04-03;62(2):278-85.
    Species: Mouse
    Sample Types: In Vivo
  70. CCR6 is required for epidermal trafficking of gammadelta-T cells in an IL-23-induced model of psoriasiform dermatitis.
    Authors: Mabuchi T, Singh T, Takekoshi T, Jia G, Wu X, Kao M, Weiss I, Farber J, Hwang S
    J Invest Dermatol, 2012-08-16;133(1):164-71.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization Control
  71. Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.
    Authors: Blotta, Simona, Jakubikova, Jana, Calimeri, Teresa, Roccaro, Aldo M, Amodio, Nicola, Azab, Abdel Ka, Foresta, Umberto, Mitsiades, Constant, Rossi, Marco, Todoerti, Katia, Molica, Stefano, Morabito, Fortunat, Neri, Antonino, Tagliaferri, Piersand, Tassone, Pierfran, Anderson, Kenneth, Munshi, Nikhil C
    Blood, 2012-07-20;120(25):5002-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry Control
  72. Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism.
    Authors: Waight JD, Hu Q, Miller A, Liu S, Abrams SI
    PLoS ONE, 2011-11-16;6(11):e27690.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  73. GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice.
    Authors: Kempf T, Zarbock A, Widera C, Butz S, Stadtmann A, Rossaint J, Bolomini-Vittori M, Korf-Klingebiel M, Napp LC, Hansen B, Kanwischer A, Bavendiek U, Beutel G, Hapke M, Sauer MG, Laudanna C, Hogg N, Vestweber D, Wollert KC
    Nat. Med., 2011-04-24;17(5):581-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  74. Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.
    Authors: Humrich JY, Morbach H, Undeutsch R, Enghard P, Rosenberger S, Weigert O, Kloke L, Heimann J, Gaber T, Brandenburg S, Scheffold A, Huehn J, Radbruch A, Burmester GR, Riemekasten G
    Proc. Natl. Acad. Sci. U.S.A., 2009-12-14;107(1):204-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  75. G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models.
    Authors: Shojaei F, Wu X, Qu X, Kowanetz M, Yu L, Tan M, Meng YG, Ferrara N
    Proc. Natl. Acad. Sci. U.S.A., 2009-04-03;106(16):6742-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  76. Rapid dendritic cell mobilization to the large intestinal epithelium is associated with resistance to Trichuris muris infection.
    Authors: Cruickshank SM, Deschoolmeester ML, Svensson M, Howell G, Bazakou A, Logunova L, Little MC, English N, Mack M, Grencis RK, Else KJ, Carding SR
    J. Immunol., 2009-03-01;182(5):3055-62.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  77. Tr1 regulatory T cells induced by ConA pretreatment prevent mice from ConA-induced hepatitis.
    Authors: Ye F, Yan S, Xu L, Jiang Z, Liu N, Xiong S, Wang Y, Chu Y
    Immunol. Lett., 2009-02-04;122(2):198-207.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  78. IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice.
    Authors: Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K
    J. Immunol., 2007-12-15;179(12):8274-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  79. Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.
    Authors: Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T
    Eur. J. Immunol., 2007-10-01;37(10):2753-63.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  80. Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation.
    Authors: Ludwig RJ, Zollner TM, Santoso S, Hardt K, Gille J, Baatz H, Johann PS, Pfeffer J, Radeke HH, Schon MP, Kaufmann R, Boehncke WH, Podda M
    J. Invest. Dermatol., 2005-11-01;125(5):969-76.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Control
  81. MIP-1 gamma promotes receptor-activator-of-NF-kappa-B-ligand-induced osteoclast formation and survival.
    Authors: Okamatsu Y, Battaglino R, Spate U, Stashenko P
    J. Immunol., 2004-08-01;173(3):2084-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization, Neutralization Control
  82. Platelets mediate inflammatory monocyte activation by SARS-CoV-2 Spike protein
    Authors: Li T, Yang Y, Li Y et al.
    The Journal of clinical investigation
  83. Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migRation through the induction of RECK.
    Authors: Siddesha Jalahalli M, Valente Anthony J, Sakamuri Siva S V P et al.
    Journal of Cellular Physiology

FAQs

  1. What is the light chain of Rat IgG1 Isotype Control, Catalog # MAB005?

    • The light chain is kappa. 

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Rat IgG1 Isotype Control
By Lu Bai on 05/06/2022
Application: Flow Sample Tested: Blood mononuclear cells (PBMCs) Species: Rat